Bioactivity behavior of biphasic calcium phosphate powders prepared by co-precipitation method

The co-precipitation technique has been applied to synthesize biphasic calcium phosphate (BCP). Ca(NO3)2 ·4 H 2O and (NH4)2HPO4 as the starting materials was used. X-ray diffraction (XRD) and Fourier transformed infrared (FT-IR) spectroscopy were used to characterize the structure of as-synthesized and calcined BCP powders. After immersion in Hanks' Balanced Salt Solution (HBSS), for 1 week a precipitation started to be formed with individual small granules on the specimen surface. An MTT assay indicated that BCP powders have no cytotoxic effects on MG-63 cells, and that they have good biocompatibility.

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