Have clinicians adopted the use of brain MRI for patients with TIA and minor stroke?

Background: Use of MRI with diffusion-weighted imaging (DWI) can identify infarcts in 30%–50% of patients with TIA. Previous guidelines have indicated that MRI-DWI is the preferred imaging modality for patients with TIA. We assessed the frequency of MRI utilization and predictors of MRI performance. Methods: A review of TIA and minor stroke patients evaluated at Veterans Affairs hospitals was conducted with regard to medical history, use of diagnostic imaging within 2 days of presentation, and in-hospital care variables. Chart abstraction was performed in a subset of hospitals to assess clinical variables not available in the administrative data. Results: A total of 7,889 patients with TIA/minor stroke were included. Overall, 6,694 patients (84.9%) had CT or MRI, with 3,396/6,694 (50.7%) having MRI. Variables that were associated with increased odds of CT performance were age >80 years, prior stroke, history of atrial fibrillation, heart failure, coronary artery disease, anxiety, and low hospital complexity, while blood pressure >140/90 mm Hg and high hospital complexity were associated with increased likelihood of MRI. Diplopia (87% had MRI, p = 0.03), neurologic consultation on the day of presentation (73% had MRI, p < 0.0001), and symptom duration of >6 hours (74% had MRI, p = 0.0009) were associated with MRI performance. Conclusions: Within a national health system, about 40% of patients with TIA/minor stroke had MRI performed within 2 days. Performance of MRI appeared to be influenced by several patient and facility-level variables, suggesting that there has been partial acceptance of the previous guideline that endorsed MRI for patients with TIA.

[1]  Edward J. Miech,et al.  Quality of Care for Veterans With Transient Ischemic Attack and Minor Stroke , 2018, JAMA neurology.

[2]  Sara K. Rostanski,et al.  Imaging Parameters and Recurrent Cerebrovascular Events in Patients With Minor Stroke or Transient Ischemic Attack. , 2016, JAMA neurology.

[3]  E. Vicaut,et al.  One-Year Risk of Stroke after Transient Ischemic Attack or Minor Stroke. , 2016, The New England journal of medicine.

[4]  D. Gelb,et al.  The impact of MRI on stroke management and outcomes: a systematic review. , 2013, Journal of evaluation in clinical practice.

[5]  J. Arenillas,et al.  Predictive value of brain and vascular imaging including intracranial vessels in transient ischaemic attack patients: external validation of the ABCD3‐I score , 2013, European journal of neurology.

[6]  M. Al-Khaled,et al.  MRI findings and stroke risk in TIA patients with different symptom durations , 2013, Neurology.

[7]  Michael D Hill,et al.  CT/CT Angiography and MRI Findings Predict Recurrent Stroke After Transient Ischemic Attack and Minor Stroke: Results of the Prospective CATCH Study , 2012, Stroke.

[8]  Theodore J Iwashyna,et al.  Wide variation and rising utilization of stroke magnetic resonance imaging: Data from 11 States , 2012, Annals of neurology.

[9]  E. V. van Dijk,et al.  Early Stroke Risk and Abcd2 Score Performance in Tissue- Vs Time-Defined Tia: A Multicenter Study , 2012, Neurology.

[10]  A. Demchuk,et al.  Early stroke risk and ABCD2 score performance in tissue- vs time-defined TIA , 2011, Neurology.

[11]  P. Savino,et al.  Neuroimaging and acute ocular motor mononeuropathies: a prospective study. , 2011, Archives of ophthalmology.

[12]  A. Demchuk,et al.  Addition of brain and carotid imaging to the ABCD2 score to identify patients at early risk of stroke after transient ischaemic attack: a multicentre observational study , 2010, The Lancet Neurology.

[13]  J. Fletcher,et al.  Incidental findings in imaging research: evaluating incidence, benefit, and burden. , 2010, Archives of internal medicine.

[14]  X. Perich,et al.  Acute brain MRI–DWI patterns and stroke recurrence after mild-moderate stroke , 2010, Journal of Neurology.

[15]  A. Hofman,et al.  Incidental findings on brain MRI in the general population. , 2007, The New England journal of medicine.

[16]  A. Demchuk,et al.  Triaging transient ischemic attack and minor stroke patients using acute magnetic resonance imaging , 2005, Annals of neurology.

[17]  W. Hacke,et al.  CT and Diffusion-Weighted MR Imaging in Randomized Order: Diffusion-Weighted Imaging Results in Higher Accuracy and Lower Interrater Variability in the Diagnosis of Hyperacute Ischemic Stroke , 2002, Stroke.

[18]  F Di Salle,et al.  Diffusion MRI in patients with transient ischemic attacks. , 1999, Stroke.

[19]  D B Matchar,et al.  What role do neurologists play in determining the costs and outcomes of stroke patients? , 1996, Stroke.