Polyamines: therapeutic perspectives in oxidative stress and inflammatory diseases

[1]  Li Luo,et al.  Agmatine Reduces Lipopolysaccharide-Mediated Oxidant Response via Activating PI3K/Akt Pathway and Up-Regulating Nrf2 and HO-1 Expression in Macrophages , 2016, PloS one.

[2]  P. Arcari,et al.  Ser/Thr kinases and polyamines in the regulation of non-canonical functions of elongation factor 1A , 2016, Amino Acids.

[3]  J. Cleveland,et al.  Targeting the polyamine-hypusine circuit for the prevention and treatment of cancer , 2016, Amino Acids.

[4]  C. Khosla,et al.  Thiol-Disulfide Exchange Reactions in the Mammalian Extracellular Environment. , 2016, Annual review of chemical and biomolecular engineering.

[5]  Puneet Kumar,et al.  Spermidine ameliorates 3-nitropropionic acid (3-NP)-induced striatal toxicity: Possible role of oxidative stress, neuroinflammation, and neurotransmitters , 2016, Physiology & Behavior.

[6]  P. Suresh,et al.  Antioxidant, DNA protective efficacy and HPLC analysis of Annona muricata (soursop) extracts , 2015, Journal of Food Science and Technology.

[7]  M. Piacentini,et al.  Transglutaminase 2 ablation leads to mitophagy impairment associated with a metabolic shift towards aerobic glycolysis , 2014, Cell Death and Differentiation.

[8]  Andiara E. Freitas,et al.  Agmatine abolishes restraint stress-induced depressive-like behavior and hippocampal antioxidant imbalance in mice , 2014, Progress in Neuro-Psychopharmacology and Biological Psychiatry.

[9]  P. Woster,et al.  Elevated ornithine decarboxylase activity promotes skin tumorigenesis by stimulating the recruitment of bulge stem cells but not via toxic polyamine catabolic metabolites , 2014, Amino Acids.

[10]  Pınar Obakan,et al.  Activation of polyamine catabolic enzymes involved in diverse responses against epibrassinolide-induced apoptosis in LNCaP and DU145 prostate cancer cell lines , 2014, Amino Acids.

[11]  L. Cynober,et al.  Aliphatic polyamines in physiology and diseases. , 2014, Clinical nutrition.

[12]  A. Pegg.  Toxicity of polyamines and their metabolic products. , 2013, Chemical research in toxicology.

[13]  W. N. Jagoe,et al.  Identification of a role for a mouse sperm surface aldo‐keto reductase (AKR1B7) and its human analogue in the detoxification of the reactive aldehyde, acrolein , 2013, Andrologia.

[14]  M. T. Veciana-Nogués,et al.  In vitro antioxidant activity of dietary polyamines , 2013 .

[15]  Yung-Hyun Choi,et al.  Anti-inflammatory effects of spermidine in lipopolysaccharide-stimulated BV2 microglial cells , 2012, Journal of Biomedical Science.

[16]  G. Melino,et al.  Type 2 transglutaminase is involved in the autophagy-dependent clearance of ubiquitinated proteins , 2012, Cell Death and Differentiation.

[17]  R. Angelini,et al.  The members of Arabidopsis thalianaPAO gene family exhibit distinct tissue- and organ-specific expression pattern during seedling growth and flower development , 2012, Amino Acids.

[18]  L. Sollid,et al.  Activation of Extracellular Transglutaminase 2 by Thioredoxin* , 2011, The Journal of Biological Chemistry.

[19]  J. E. Lee,et al.  Effects of agmatine on hypoxic microglia and activity of nitric oxide synthase , 2011, Brain Research.

[20]  S. Kojima,et al.  Brain infarction correlates more closely with acrolein than with reactive oxygen species. , 2011, Biochemical and biophysical research communications.

[21]  K. Ljung,et al.  Role of polyamines in plant vascular development. , 2010, Plant physiology and biochemistry : PPB.

[22]  K. Ha,et al.  Transglutaminase 2: a multi-functional protein in multiple subcellular compartments , 2010, Amino Acids.

[23]  A. Pegg.  Mammalian polyamine metabolism and function , 2009, IUBMB life.

[24]  A. Pegg,et al.  Polyamine catabolism and disease. , 2009, The Biochemical journal.

[25]  J. E. Lee,et al.  Neuroprotective effects of agmatine on oxygen-glucose deprived primary-cultured astrocytes and nuclear translocation of nuclear factor-kappa B , 2009, Brain Research.

[26]  Orly Dym,et al.  Crystallographic and biochemical studies revealing the structural basis for antizyme inhibitor function , 2008, Protein science : a publication of the Protein Society.

[27]  S. Naik,et al.  Polyamines: Potential anti-inflammatory agents and their possible mechanism of action , 2008, Indian journal of pharmacology.

[28]  G. Wu,et al.  Proline metabolism in the conceptus: implications for fetal growth and development , 2008, Amino Acids.

[29]  S. Merali,et al.  Polyamine Acetylation Modulates Polyamine Metabolic Flux, a Prelude to Broader Metabolic Consequences* , 2008, Journal of Biological Chemistry.

[30]  A. Brunger,et al.  Transglutaminase 2 Undergoes a Large Conformational Change upon Activation , 2007, PLoS biology.

[31]  L. Alhonen,et al.  Oxidative stress and inflammation in the pathogenesis of activated polyamine catabolism-induced acute pancreatitis , 2007, Amino Acids.

[32]  J. D. Bandt,et al.  Métabolisme et fonctions des polyamines , 2006 .

[33]  R. Casero,et al.  Tumor necrosis factor alpha increases reactive oxygen species production and induces DNA damage by inducing spermine oxidase in human lung bronchial epithelial cells in vitro: Potential mechanism for inflammation induced lung carcinogenesis. , 2006 .

[34]  R. Casero,et al.  Tumor necrosis factor-alpha increases reactive oxygen species by inducing spermine oxidase in human lung epithelial cells: a potential mechanism for inflammation-induced carcinogenesis. , 2006, Cancer research.

[35]  A. Keren-Paz,et al.  Overexpression of antizyme-inhibitor in NIH3T3 fibroblasts provides growth advantage through neutralization of antizyme functions , 2006, Oncogene.

[36]  U. Mangold.  Antizyme inhibitor: mysterious modulator of cell proliferation , 2006, Cellular and Molecular Life Sciences CMLS.

[37]  A. Pegg.  Regulation of Ornithine Decarboxylase* , 2006, Journal of Biological Chemistry.

[38]  Marcela S. Sanchez,et al.  Polyamines as a defense mechanism against lipoperoxidation in Trypanosoma cruzi. , 2006, Acta tropica.

[39]  Eugene W Gerner,et al.  Induction of spermidine/spermine N1-acetyltransferase (SSAT) by aspirin in Caco-2 colon cancer cells. , 2006, The Biochemical journal.

[40]  N. Seiler,et al.  Polyamines and apoptosis , 2005, Journal of cellular and molecular medicine.

[41]  K. Kasono,et al.  Spermine, a Natural Polyamine, Suppresses LFA-1 Expression on Human Lymphocyte , 2005, The Journal of Immunology.

[42]  E. Gerner,et al.  Polyamines and cancer: old molecules, new understanding , 2004, Nature Reviews Cancer.

[43]  G. Rogler,et al.  Intracellular Polyamine Levels of Intestinal Epithelial Cells in Inflammatory Bowel Disease , 2004, Inflammatory bowel diseases.

[44]  G. Arancia,et al.  The biological functions of polyamine oxidation products by amine oxidases: Perspectives of clinical applications , 2004, Amino Acids.

[45]  O. Peulen,et al.  Differential effect of dietary spermine on alkaline phosphatase activity in jejunum and ileum of unweaned rats. , 2004, Biochimie.

[46]  A. Calcabrini,et al.  Mitochondrial alterations induced by serum amine oxidase and spermine on human multidrug resistant tumor cells , 2004, Amino Acids.

[47]  A. Pegg,et al.  Putrescine biosynthesis in mammalian tissues. , 2004, The Biochemical journal.

[48]  F. Pérez-Cano,et al.  Immunomodulatory action of spermine and spermidine on NR8383 macrophage line in various culture conditions. , 2003, Cellular immunology.

[49]  W. Plunkett,et al.  Inhibition of Mitochondrial Respiration , 2003, Journal of Biological Chemistry.

[50]  S. Rivest,et al.  Polyamines play a critical role in the control of the innate immune response in the mouse central nervous system , 2003, The Journal of cell biology.

[51]  E. Gerner,et al.  Polyamine-dependent gene expression , 2003, Cellular and Molecular Life Sciences CMLS.

[52]  Judith E. Cartwright,et al.  Nitric oxide inhibits polyamine-induced apoptosis in the human extravillous trophoblast cell line SGHPL-4. , 2003, Human reproduction.

[53]  C. W. Tabor,et al.  Polyamines protect Escherichia coli cells from the toxic effect of oxygen , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[54]  D. Kramer,et al.  Genomic identification and biochemical characterization of the mammalian polyamine oxidase involved in polyamine back-conversion. , 2003, The Biochemical journal.

[55]  J. Lai,et al.  Agmatine modulates the in vivo biosynthesis and interconversion of polyamines and cell proliferation. , 2003, Biochimica et biophysica acta.

[56]  R. Casero,et al.  Cloning and characterization of multiple human polyamine oxidase splice variants that code for isoenzymes with different biochemical characteristics. , 2002, The Biochemical journal.

[57]  Rita Casadio,et al.  Transglutaminases: nature's biological glues. , 2002, The Biochemical journal.

[58]  Guoyao Wu,et al.  Free radicals, antioxidants, and nutrition. , 2002, Nutrition.

[59]  Mauro Piacentini,et al.  Transglutaminase 2: an enigmatic enzyme with diverse functions. , 2002, Trends in biochemical sciences.

[60]  H. Wallace,et al.  Insufficiently charged isosteric analogue of spermine: interaction with polyamine uptake, and effect on Caco-2 cell growth. , 2002, Biochemical pharmacology.

[61]  P. Kalač,et al.  Levels of biogenic amines in typical vegetable products , 2002 .

[62]  W. Grody,et al.  Cloning and characterization of human agmatinase. , 2002, Molecular genetics and metabolism.

[63]  J. Klinman,et al.  Rates of oxygen and hydrogen exchange as indicators of TPQ cofactor orientation in amine oxidases. , 2002, Biochemistry.

[64]  C. Cabella,et al.  Agmatine modulates polyamine content in hepatocytes by inducing spermidine/spermine acetyltransferase. , 2001, European journal of biochemistry.

[65]  L. Pfeffer,et al.  Polyamine Depletion Induces Rapid NF-κB Activation in IEC-6 Cells* , 2001, The Journal of Biological Chemistry.

[66]  F. Sánchez-Jiménez,et al.  Polyamine metabolism revisited. , 2001, European journal of gastroenterology & hepatology.

[67]  B. Bass,et al.  NF-κB activation and susceptibility to apoptosis after polyamine depletion in intestinal epithelial cells , 2001 .

[68]  S. Iwasaki,et al.  Polyamine cytotoxicity in the presence of bovine serum amine oxidase. , 2001, Biochemical and biophysical research communications.

[69]  M. Burns,et al.  Novel lysine-spermine conjugate inhibits polyamine transport and inhibits cell growth when given with DFMO. , 2000, Experimental cell research.

[70]  D. Reis,et al.  Is agmatine a novel neurotransmitter in brain? , 2000, Trends in pharmacological sciences.

[71]  Hong Wang,et al.  Regulation of macrophage activation and inflammation by spermine: a new chapter in an old story. , 2000, Critical care medicine.

[72]  R. Dempsey,et al.  Elevated N1‐Acetylspermidine Levels in Gerbil and Rat Brains After CNS Injury , 2000, Journal of neurochemistry.

[73]  P. Skolnick,et al.  Spermine‐Induced Toxicity in Cerebellar Granule Neurons Is Independent of Its Actions at NMDA Receptors , 2000, Journal of neurochemistry.

[74]  T. Thomas,et al.  Activation of nuclear factor kappaB by polyamines in breast cancer cells. , 1999, Biochemistry.

[75]  Guoyao Wu,et al.  Arginine metabolism: nitric oxide and beyond. , 1998, The Biochemical journal.

[76]  H. Checkoway,et al.  A genetic polymorphism of MAO-B modifies the association of cigarette smoking and Parkinson's disease , 1998, Neurology.

[77]  S. Matsufuji,et al.  Cloning and sequencing of a human cDNA encoding ornithine decarboxylase antizyme inhibitor. , 1997, Biochimica et biophysica acta.

[78]  G. Grant,et al.  The importance of dietary polyamines in cell regeneration and growth , 1995, British Journal of Nutrition.

[79]  A. Shirahata,et al.  Specific depletion of spermidine and spermine in HTC cells treated with inhibitors of aminopropyltransferases. , 1995, Journal of biochemistry.

[80]  U. Bachrach,et al.  Activation of the proto-oncogene c-myc and c-fos by c-ras: involvement of polyamines. , 1994, Biochemical and biophysical research communications.

[81]  J. Mathai,et al.  Stretch sensitivity of transmembrane mobility of hydrogen peroxide through voids in the bilayer. Role of cardiolipin. , 1994, The Journal of biological chemistry.

[82]  C. Thiemermann,et al.  Inhibition by spermine of the induction of nitric oxide synthase in J774.2 macrophages: requirement of a serum factor , 1994, British journal of pharmacology.

[83]  C. Franceschi,et al.  A new method for the cytofluorimetric analysis of mitochondrial membrane potential using the J-aggregate forming lipophilic cation 5,5',6,6'-tetrachloro-1,1',3,3'-tetraethylbenzimidazolcarbocyanine iodide (JC-1). , 1993, Biochemical and biophysical research communications.

[84]  P. Di Mascio,et al.  Spermine and spermidine protection of plasmid DNA against single-strand breaks induced by singlet oxygen. , 1992, Proceedings of the National Academy of Sciences of the United States of America.

[85]  P. Woster,et al.  S-(5'-deoxy-5'-adenosyl)-1-ammonio-4-(methylsulfonio)-2-cyclopentene: A potent, enzyme-activated irreversible inhibitor of S-adenosylmethionine decarboxylase. , 1992, Journal of medicinal chemistry.

[86]  C. Porter,et al.  Inhibition of enzymes of polyamine back-conversion by pentamidine and berenil. , 1992, Biochemical pharmacology.

[87]  L. Johnson,et al.  Role of polyamines in gastrointestinal mucosal growth. , 1991, The American journal of physiology.

[88]  T. Eloranta,et al.  Aminooxy analogues of spermidine as inhibitors of spermine synthase and substrates of hepatic polyamine acetylating activity. , 1990, Journal of biochemistry.

[89]  C. Danzin,et al.  Irreversible inhibition of rat S-adenosylmethionine decarboxylase by 5'-([(Z)-4-amino-2-butenyl]methylamino)-5'-deoxyadenosine. , 1990, Biochemical pharmacology.

[90]  W. Creutzfeldt,et al.  Polyamines in colorectal cancer. Evaluation of polyamine concentrations in the colon tissue, serum, and urine of 50 patients with colorectal cancer , 1990, Cancer.

[91]  J. Keij,et al.  Microbial flora in the gastrointestinal tract abolishes cytostatic effects of α‐difluoromethylornithine in vivo , 1989, International journal of cancer.

[92]  P. Rada,et al.  Agmatine Induces Nrf2 and Protects Against Corticosterone Effects in Hippocampal Neuronal Cell Line , 2014, Molecular Neurobiology.

[93]  A. Pegg,et al.  Current status of the polyamine research field. , 2011, Methods in molecular biology.

[94]  L. Andersson,et al.  Human ornithine decarboxylase paralogue (ODCp) is an antizyme inhibitor but not an arginine decarboxylase. , 2008, The Biochemical journal.

[95]  M. Kelly,et al.  Study of polyamines and their precursor amino acids in Grenache noir and Syrah grapes and wine of the Rhone Valley , 2007 .

[96]  D. Telci,et al.  Tissue transglutaminase (TG2)--a wound response enzyme. , 2006, Frontiers in bioscience : a journal and virtual library.

[97]  H. Barbieri,et al.  Swedish Nutrition Recommendations Objectified , 2005 .

[98]  B. Bass,et al.  NF-kappaB activation and susceptibility to apoptosis after polyamine depletion in intestinal epithelial cells. , 2001, American journal of physiology. Gastrointestinal and liver physiology.

[99]  L. Pfeffer,et al.  Polyamine depletion induces rapid NF-kappa B activation in IEC-6 cells. , 2001, The Journal of biological chemistry.

[100]  C. Bergeron,et al.  Erythrocyte spermine levels: a prognostic parameter in childhood common acute lymphoblastic leukemia , 1997, Leukemia.

[101]  L. Marton,et al.  Polyamines as targets for therapeutic intervention. , 1995, Annual review of pharmacology and toxicology.

[102]  N. Seiler,et al.  The natural polyamines and the immune system. , 1994, Progress in drug research. Fortschritte der Arzneimittelforschung. Progres des recherches pharmaceutiques.

[103]  G. Carlin,et al.  Spermine: an anti-oxidant and anti-inflammatory agent. , 1991, Free radical biology & medicine.

[104]  N. Seiler,et al.  Polyamine metabolism. , 1990, Digestion.

[105]  A. Galston,et al.  7 – Polyamine Metabolism , 1990 .

[106]  C. W. Tabor,et al.  Methionine adenosyltransferase (S-adenosylmethionine synthetase) and S-adenosylmethionine decarboxylase. , 1984 .