Chronic liver inflammation modifies DNA methylation at the precancerous stage of murine hepatocarcinogenesis
暂无分享,去创建一个
H. Cedar | R. Schinazi | E. Galun | P. Vertino | G. Tiegs | D. Goldenberg | Lina Mizrahi | J. Kohler | E. Stoyanov | G. Sass | E. Tasika | Guy Ludwig | Devorah Olam | Yong Jiang | Ting Nie | Temima Schnitzer-Perlman
[1] C. Lian,et al. Decrease of 5‐hydroxymethylcytosine in rat liver with subchronic exposure to genotoxic carcinogens riddelliine and aristolochic acid , 2015, Molecular carcinogenesis.
[2] K. Rithidech,et al. Induction of chronic oxidative stress, chronic inflammation and aberrant patterns of DNA methylation in the liver of titanium-exposed CBA/CaJ mice , 2015, International journal of radiation biology.
[3] Stephanie A. Tammen,et al. Aging Alters Hepatic DNA Hydroxymethylation, as Measured by Liquid Chromatography/Mass Spectrometry , 2014, Journal of cancer prevention.
[4] I. Steinfeld,et al. Specific genomic and transcriptomic aberrations in tumors induced by partial hepatectomy of a chronically inflamed murine liver , 2014, Oncotarget.
[5] Kevin Y. Yip,et al. Whole-genome bisulfite sequencing of multiple individuals reveals complementary roles of promoter and gene body methylation in transcriptional regulation , 2014, Genome Biology.
[6] O. Yanuka,et al. Aberrant DNA Methylation in ES Cells , 2014, PloS one.
[7] Richard J. Thompson,et al. Massive gene amplification drives paediatric hepatocellular carcinoma caused by bile salt export pump deficiency , 2014, Nature Communications.
[8] Jia Fan,et al. High expression of 5-hydroxymethylcytosine and isocitrate dehydrogenase 2 is associated with favorable prognosis after curative resection of hepatocellular carcinoma , 2014, Journal of experimental & clinical cancer research : CR.
[9] Israel Steinfeld,et al. Molecular and Cellular Pathobiology Molecular Rules Governing De Novo Methylation in Cancer , 2022 .
[10] Yi Zhang,et al. TET enzymes, TDG and the dynamics of DNA demethylation , 2013, Nature.
[11] Zizhen Yao,et al. Fundamental differences in promoter CpG island DNA hypermethylation between human cancer and genetically engineered mouse models of cancer , 2013, Epigenetics.
[12] S. Horvath. DNA methylation age of human tissues and cell types , 2013, Genome Biology.
[13] Ido D. Weiss,et al. Inflammation‐induced hepatocellular carcinoma is dependent on CCR5 in mice , 2013, Hepatology.
[14] M. Kals,et al. Ontogeny, distribution and potential roles of 5-hydroxymethylcytosine in human liver function , 2013, Genome Biology.
[15] N. Shimoda,et al. Transient reduction of 5-methylcytosine and 5-hydroxymethylcytosine is associated with active DNA demethylation during regeneration of zebrafish fin , 2013, Epigenetics.
[16] Evgeniy Stoyanov,et al. Interstrain differences in chronic hepatitis and tumor development in a murine model of inflammation‐mediated hepatocarcinogenesis , 2013, Hepatology.
[17] A. Miyajima,et al. To divide or not to divide: revisiting liver regeneration , 2013, Cell Division.
[18] Limei Liu,et al. Decrease of 5-Hydroxymethylcytosine Is Associated with Progression of Hepatocellular Carcinoma through Downregulation of TET1 , 2013, PloS one.
[19] A. Andriulli,et al. Associations between Genetic Polymorphisms in IL-33, IL1R1 and Risk for Inflammatory Bowel Disease , 2013, PloS one.
[20] P. Meltzer,et al. Succinate dehydrogenase mutation underlies global epigenomic divergence in gastrointestinal stromal tumor. , 2013, Cancer discovery.
[21] Howard Cedar,et al. DNA methylation dynamics in health and disease , 2013, Nature Structural &Molecular Biology.
[22] Gordon Okimoto,et al. Elucidating the Landscape of Aberrant DNA Methylation in Hepatocellular Carcinoma , 2013, PloS one.
[23] Frank Lyko,et al. Combined deficiency of Tet1 and Tet2 causes epigenetic abnormalities but is compatible with postnatal development. , 2013, Developmental cell.
[24] Z. Ling,et al. Tumor development is associated with decrease of TET gene expression and 5-methylcytosine hydroxylation , 2013, Oncogene.
[25] J. Cherfils,et al. Fam65b Is a New Transcriptional Target of FOXO1 That Regulates RhoA Signaling for T Lymphocyte Migration , 2013, The Journal of Immunology.
[26] Olaf Neumann,et al. Methylome analysis and integrative profiling of human HCCs identify novel protumorigenic factors , 2012, Hepatology.
[27] Colm E. Nestor,et al. Tissue of origin determines cancer-associated CpG island promoter hypermethylation patterns , 2012, Genome Biology.
[28] J. Stauffer,et al. Chronic inflammation, immune escape, and oncogenesis in the liver: A unique neighborhood for novel intersections , 2012, Hepatology.
[29] M. Kudo,et al. Characteristic patterns of altered DNA methylation predict emergence of human hepatocellular carcinoma , 2012, Hepatology.
[30] R. Siebert,et al. Distinct DNA methylation patterns in cirrhotic liver and hepatocellular carcinoma , 2012, International journal of cancer.
[31] Z. Herceg,et al. From hepatitis to hepatocellular carcinoma: a proposed model for cross-talk between inflammation and epigenetic mechanisms , 2012, Genome Medicine.
[32] G. Schackert,et al. 5-Hydroxymethylcytosine is strongly depleted in human cancers but its levels do not correlate with IDH1 mutations. , 2011, Cancer research.
[33] Y. Kanai,et al. Carcinogenetic risk estimation based on quantification of DNA methylation levels in liver tissue at the precancerous stage , 2011, International journal of cancer.
[34] M. Szyf,et al. Definition of the landscape of promoter DNA hypomethylation in liver cancer. , 2011, Cancer research.
[35] Weiwei Li,et al. Distribution of 5-Hydroxymethylcytosine in Different Human Tissues , 2011, Journal of nucleic acids.
[36] Z. Herceg,et al. Epigenetic mechanisms in hepatocellular carcinoma: how environmental factors influence the epigenome. , 2011, Mutation research.
[37] M. Takasugi. Progressive age-dependent DNA methylation changes start before adulthood in mouse tissues , 2011, Mechanisms of Ageing and Development.
[38] N. Iizuka,et al. Efficient detection of hepatocellular carcinoma by a hybrid blood test of epigenetic and classical protein markers. , 2011, Clinica chimica acta; international journal of clinical chemistry.
[39] Sean V. Tavtigian,et al. Hepatocellular Carcinoma Displays Distinct DNA Methylation Signatures with Potential as Clinical Predictors , 2010, PloS one.
[40] Yae Kanai,et al. Genome‐wide DNA methylation profiles in precancerous conditions and cancers , 2010, Cancer science.
[41] N. Iizuka,et al. The assessment of methylated BASP1 and SRD5A2 levels in the detection of early hepatocellular carcinoma. , 2009, International journal of oncology.
[42] M. T. McCabe,et al. Cancer DNA Methylation: Molecular Mechanisms and Clinical Implications , 2009, Clinical Cancer Research.
[43] K. Wallace,et al. Interleukin-1 participates in the progression from liver injury to fibrosis. , 2009, American journal of physiology. Gastrointestinal and liver physiology.
[44] Israel Steinfeld,et al. Developmental programming of CpG island methylation profiles in the human genome , 2009, Nature Structural &Molecular Biology.
[45] G. Tiegs,et al. Down-regulation of the De-ubiquitinating Enzyme Ubiquitin-specific Protease 2 Contributes to Tumor Necrosis Factor-α-induced Hepatocyte Survival* , 2009, Journal of Biological Chemistry.
[46] A. Riggs,et al. Methylation of polycomb target genes in intestinal cancer is mediated by inflammation. , 2008, Cancer research.
[47] C. Boland,et al. Aberrant methylation of multiple tumor suppressor genes in aging liver, chronic hepatitis, and hepatocellular carcinoma , 2008, Hepatology.
[48] Eytan Domany,et al. Molecular Mechanisms of Liver Carcinogenesis in the Mdr2-Knockout Mice , 2007, Molecular Cancer Research.
[49] S. Thorgeirsson,et al. Mechanistic and prognostic significance of aberrant methylation in the molecular pathogenesis of human hepatocellular carcinoma. , 2007, The Journal of clinical investigation.
[50] Eytan Domany,et al. Multiple adaptive mechanisms to chronic liver disease revealed at early stages of liver carcinogenesis in the Mdr2-knockout mice. , 2006, Cancer research.
[51] I. Simon,et al. Evidence for an instructive mechanism of de novo methylation in cancer cells , 2006, Nature Genetics.
[52] Suman Lee,et al. Estimating the total mouse DNA methylation according to the B1 repetitive elements. , 2005, Biochemical and biophysical research communications.
[53] R. Jaenisch,et al. Opposing effects of DNA hypomethylation on intestinal and liver carcinogenesis. , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[54] Y. Ben-Neriah,et al. NF-κB functions as a tumour promoter in inflammation-associated cancer , 2004, Nature.
[55] H. Tilg,et al. Regurgitation of bile acids from leaky bile ducts causes sclerosing cholangitis in Mdr2 (Abcb4) knockout mice. , 2004, Gastroenterology.
[56] Yau-Huei Wei,et al. Somatic mutations in the D-loop and decrease in the copy number of mitochondrial DNA in human hepatocellular carcinoma. , 2004, Mutation research.
[57] Hyeon Joo Lee,et al. Aberrant CpG island hypermethylation along multistep hepatocarcinogenesis. , 2003, The American journal of pathology.
[58] Long-Cheng Li,et al. MethPrimer: designing primers for methylation PCRs , 2002, Bioinform..
[59] A. Nakao,et al. Human livers with cirrhosis and hepatocellular carcinoma have less mitochondrial DNA deletion than normal human livers. , 1999, Life sciences.
[60] S. Baylin. Tying It All Together: Epigenetics, Genetics, Cell Cycle, and Cancer , 1997, Science.
[61] A. Tanaka,et al. The frequency of 4977 base pair deletion of mitochondrial DNA in various types of liver disease and in normal liver , 1995, Hepatology.
[62] A. Groen,et al. Mice with homozygous disruption of the mdr2 P-glycoprotein gene. A novel animal model for studies of nonsuppurative inflammatory cholangitis and hepatocarcinogenesis. , 1994, The American journal of pathology.
[63] Stephan Beck,et al. Inflammatory signalling as mediator of epigenetic modulation in tissue-specific chronic inflammation. , 2009, The international journal of biochemistry & cell biology.
[64] Dirk Schübeler,et al. Methylated DNA immunoprecipitation (MeDIP). , 2009, Methods in molecular biology.
[65] Rinat Abramovitch,et al. NF-kappaB functions as a tumour promoter in inflammation-associated cancer. , 2004, Nature.
[66] S Rozen,et al. Primer3 on the WWW for general users and for biologist programmers. , 2000, Methods in molecular biology.