Cell growth inhibition and induction of apoptosis by snake venom toxin in ovarian cancer cell via inactivation of nuclear factor κB and signal transducer and activator of transcription 3
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J. Hong | M. Park | Miran Jo | S. Han | B. An | H. Song | Ju-Kyoung Song | M. J. Song
[1] D. Roberts,et al. Mammalian Target of Rapamycin Is a Therapeutic Target for Murine Ovarian Endometrioid Adenocarcinomas with Dysregulated Wnt/β-Catenin and PTEN , 2011, PLoS ONE.
[2] V. Galic,et al. Paclitaxel poliglumex for ovarian cancer , 2011, Expert opinion on investigational drugs.
[3] C. Chien,et al. Taiwan cobra cardiotoxin III inhibits Src kinase leading to apoptosis and cell cycle arrest of oral squamous cell carcinoma Ca9-22 cells. , 2010, Toxicon : official journal of the International Society on Toxinology.
[4] A. Jemal,et al. Cancer Statistics, 2010 , 2010, CA: a cancer journal for clinicians.
[5] S. Steinberg,et al. Nuclear factor κB transcription factors are coexpressed and convey a poor outcome in ovarian cancer , 2010, Cancer.
[6] C. Chien,et al. Down-regulation of the JAK2/PI3K-mediated signaling activation is involved in Taiwan cobra cardiotoxin III-induced apoptosis of human breast MDA-MB-231 cancer cells. , 2010, Toxicon : official journal of the International Society on Toxinology.
[7] T. Kálai,et al. Anticancer Efficacy of a Difluorodiarylidenyl Piperidone (HO-3867) in Human Ovarian Cancer Cells and Tumor Xenografts , 2010, Molecular Cancer Therapeutics.
[8] A. Singh,et al. p65 Negatively Regulates Transcription of the Cyclin E Gene* , 2010, The Journal of Biological Chemistry.
[9] J. Hong,et al. Snake venom toxin inhibits cell growth through induction of apoptosis in neuroblastoma cells , 2009, Archives of pharmacal research.
[10] Hua Yu,et al. STATs in cancer inflammation and immunity: a leading role for STAT3 , 2009, Nature Reviews Cancer.
[11] Hua Yu,et al. Persistently activated Stat3 maintains constitutive NF-kappaB activity in tumors. , 2009, Cancer cell.
[12] K. Takeda,et al. Regulation of host immune responses by nuclear IκB proteins , 2008 .
[13] Q. Yao,et al. Mesothelin-Induced Pancreatic Cancer Cell Proliferation Involves Alteration of Cyclin E via Activation of Signal Transducer and Activator of Transcription Protein 3 , 2008, Molecular Cancer Research.
[14] Matthew S. Hayden,et al. New regulators of NF-κB in inflammation , 2008, Nature Reviews Immunology.
[15] Liz Y. Han,et al. Curcumin Inhibits Tumor Growth and Angiogenesis in Ovarian Carcinoma by Targeting the Nuclear Factor-κB Pathway , 2007, Clinical Cancer Research.
[16] Jae Woong Lee,et al. Inhibitory effect of snake venom toxin from Vipera lebetina turanica on hormone-refractory human prostate cancer cell growth: induction of apoptosis through inactivation of nuclear factor κB , 2007, Molecular Cancer Therapeutics.
[17] K. W. Kim,et al. Inhibition of signal transducer and activator of transcription 3 activity results in down-regulation of Survivin following irradiation , 2006, Molecular Cancer Therapeutics.
[18] Zhenfeng Duan,et al. Signal Transducers and Activators of Transcription 3 Pathway Activation in Drug-Resistant Ovarian Cancer , 2006, Clinical Cancer Research.
[19] M. Karin. Nuclear factor-κB in cancer development and progression , 2006, Nature.
[20] D. Yoon,et al. Cobrotoxin inhibits NF-κB activation and target gene expression through reaction with NF-κB signal molecules , 2005 .
[21] M. Kuo,et al. Up-regulation of interleukin-6 in human ovarian cancer cell via a Gi/PI3K-Akt/NF-kappaB pathway by lysophosphatidic acid, an ovarian cancer-activating factor. , 2004, Carcinogenesis.
[22] Sankar Ghosh,et al. Signaling to NF-kappaB. , 2004, Genes & development.
[23] M. Grant,et al. Conotoxins and structural biology: a prospective paradigm for drug discovery. , 2004, Current protein & peptide science.
[24] Pingfu Fu,et al. Nuclear factor-kappaB/p65 (Rel A) is constitutively activated in human prostate adenocarcinoma and correlates with disease progression. , 2004, Neoplasia.
[25] Wenjun Cheng,et al. Activated Signal Transducer and Activator of Transcription (STAT) 3 , 2004, Cancer Research.
[26] N. Perkins,et al. Active Repression of Antiapoptotic Gene Expression by RelA(p65) NF-κB , 2004 .
[27] F. Laraba-Djebari,et al. Evaluation of the effect of gamma rays on the venom of Vipera lebetina by biochemical study. , 2003, Canadian journal of physiology and pharmacology.
[28] W. You,et al. The snake venom disintegrin salmosin induces apoptosis by disassembly of focal adhesions in bovine capillary endothelial cells. , 2003, Biochemical and biophysical research communications.
[29] D. Armstrong. Relapsed ovarian cancer: challenges and management strategies for a chronic disease. , 2002, The oncologist.
[30] Michael Karin,et al. NF-κB in cancer: from innocent bystander to major culprit , 2002, Nature Reviews Cancer.
[31] P. Quesenberry,et al. Coexpression of oncostatin M and its receptors and evidence for STAT3 activation in human ovarian carcinomas. , 2002, Cytokine.
[32] Jiayuh Lin,et al. Inhibition of constitutively active Stat3 suppresses growth of human ovarian and breast cancer cells , 2001, Oncogene.
[33] E Siigur,et al. Sequence diversity of Vipera lebetina snake venom gland serine proteinase homologs--result of alternative-splicing or genome alteration. , 2001, Gene.
[34] Jiayuh Lin,et al. Constitutive activation of stat 3 oncogene product in human ovarian carcinoma cells. , 2000, Gynecologic oncology.
[35] C. Bucana,et al. Blockade of nuclear factor-kappaB signaling inhibits angiogenesis and tumorigenicity of human ovarian cancer cells by suppressing expression of vascular endothelial growth factor and interleukin 8. , 2000, Cancer research.
[36] G. Mourier,et al. Relative Spatial Position of a Snake Neurotoxin and the Reduced Disulfide Bond α(Cys192-Cys193) at the αγ Interface of the Nicotinic Acetylcholine Receptor* , 2000, The Journal of Biological Chemistry.
[37] W. Greene,et al. Protein Kinase C-θ Participates in NF-κB Activation Induced by CD3-CD28 Costimulation through Selective Activation of IκB Kinase β , 2000, Molecular and Cellular Biology.
[38] C. Geisler,et al. Inhibition of constitutively activated Stat3 correlates with altered Bcl-2/Bax expression and induction of apoptosis in mycosis fungoides tumor cells , 1999, Leukemia.
[39] J C Reed,et al. IAP family proteins--suppressors of apoptosis. , 1999, Genes & development.
[40] D Bertrand,et al. Only Snake Curaremimetic Toxins with a Fifth Disulfide Bond Have High Affinity for the Neuronal α7 Nicotinic Receptor* , 1997, The Journal of Biological Chemistry.
[41] A. Tu,et al. cDNA Cloning and Deduced Amino Acid Sequence of Fibrinolytic Enzyme (Lebetase) fromVipera lebetinaSnake Venom , 1996 .
[42] S. Reed,et al. Association of human cyclin E with a periodic G1-S phase protein kinase. , 1992, Science.
[43] James M. Roberts,et al. Formation and activation of a cyclin E-cdk2 complex during the G1 phase of the human cell cycle , 1992 .
[44] E. Hatzipantelis,et al. Ovarian tumours in childhood and adolescence. , 2010, European journal of gynaecological oncology.
[45] C. Chien,et al. Effects of cardiotoxin III on NF-kappaB function, proliferation, and apoptosis in human breast MCF-7 cancer cells. , 2009, Oncology research.
[46] K. Takeda,et al. Role of nuclear IκB proteins in the regulation of host immune responses , 2008, Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy.
[47] M. Karin. Nuclear factor-kappaB in cancer development and progression. , 2006, Nature.
[48] N. Perkins,et al. Active repression of antiapoptotic gene expression by RelA(p65) NF-kappa B. , 2004, Molecular cell.
[49] Sung-Yu Hong,et al. Snake venom disintegrin, saxatilin, inhibits platelet aggregation, human umbilical vein endothelial cell proliferation, and smooth muscle cell migration. , 2002, Thrombosis research.
[50] Michael Karin,et al. NF-kappaB in cancer: from innocent bystander to major culprit. , 2002, Nature reviews. Cancer.
[51] W. Greene,et al. Protein kinase C-theta participates in NF-kappaB activation induced by CD3-CD28 costimulation through selective activation of IkappaB kinase beta. , 2000, Molecular and Cellular Biology.
[52] A. Tu,et al. cDNA cloning and deduced amino acid sequence of fibrinolytic enzyme (lebetase) from Vipera lebetina snake venom. , 1996, Biochemical and biophysical research communications.