Metastasis-suppressor transcript destabilization through TARBP2 binding of mRNA hairpins

[1]  Saeed Tavazoie,et al.  Systematic identification of regulatory elements in conserved 3' UTRs of human transcripts. , 2014, Cell reports.

[2]  Ugo Ala,et al.  MicroRNA-Antagonism Regulates Breast Cancer Stemness and Metastasis via TET-Family-Dependent Chromatin Remodeling , 2013, Cell.

[3]  Brendan J. Frey,et al.  A compendium of RNA-binding motifs for decoding gene regulation , 2013, Nature.

[4]  J. Manley SELEX to identify protein-binding sites on RNA. , 2013, Cold Spring Harbor protocols.

[5]  S. Tavazoie,et al.  Convergent Multi-miRNA Targeting of ApoE Drives LRP1/LRP8-Dependent Melanoma Metastasis and Angiogenesis , 2012, Cell.

[6]  Gabriele Varani,et al.  Faculty Opinions recommendation of Systematic discovery of structural elements governing stability of mammalian messenger RNAs. , 2012 .

[7]  Nicolò Riggi,et al.  A TARBP2-dependent miRNA expression profile underlies cancer stem cell properties and provides candidate therapeutic reagents in Ewing sarcoma. , 2012, Cancer cell.

[8]  Howard Y. Chang,et al.  Understanding the transcriptome through RNA structure , 2011, Nature Reviews Genetics.

[9]  Olivier Elemento,et al.  An integrated ChIP-seq analysis platform with customizable workflows , 2011, BMC Bioinformatics.

[10]  R. Darnell,et al.  Mapping in vivo protein-RNA interactions at single-nucleotide resolution from HITS-CLIP data , 2011, Nature Biotechnology.

[11]  Jiannis Ragoussis,et al.  Direct targeting of Sec23a by miR-200s influences cancer cell secretome and promotes metastatic colonization , 2011, Nature Medicine.

[12]  L. Esserman,et al.  A genomic predictor of response and survival following taxane-anthracycline chemotherapy for invasive breast cancer. , 2011, JAMA.

[13]  T. Meshel,et al.  Inflammatory mediators in breast cancer: Coordinated expression of TNFα & IL-1β with CCL2 & CCL5 and effects on epithelial-to-mesenchymal transition , 2011, BMC Cancer.

[14]  Howard Y. Chang,et al.  Genome-wide measurement of RNA secondary structure in yeast , 2010, Nature.

[15]  E. Kremmer,et al.  ADAM10 is the physiologically relevant, constitutive α‐secretase of the amyloid precursor protein in primary neurons , 2010, The EMBO journal.

[16]  Cole Trapnell,et al.  Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation. , 2010, Nature biotechnology.

[17]  Xin Li,et al.  miR-20a promotes proliferation and invasion by targeting APP in human ovarian cancer cells. , 2010, Acta biochimica et biophysica Sinica.

[18]  M. Kiebler,et al.  Faculty Opinions recommendation of Argonaute HITS-CLIP decodes microRNA-mRNA interaction maps. , 2009 .

[19]  Lourdes Peña Castillo,et al.  Rapid and systematic analysis of the RNA recognition specificities of RNA-binding proteins , 2009, Nature Biotechnology.

[20]  Barrett C. Foat,et al.  Discovering structural cis-regulatory elements by modeling the behaviors of mRNAs , 2009, Molecular systems biology.

[21]  S. Salzberg,et al.  TopHat: discovering splice junctions with RNA-Seq , 2009, Bioinform..

[22]  Klaus Rajewsky,et al.  MicroRNA Control in the Immune System: Basic Principles , 2009, Cell.

[23]  Tyson A. Clark,et al.  HITS-CLIP yields genome-wide insights into brain alternative RNA processing , 2008, Nature.

[24]  R. Zimmer,et al.  High-resolution gene expression profiling for simultaneous kinetic parameter analysis of RNA synthesis and decay. , 2008, RNA.

[25]  Miriam K. Konkel,et al.  Genome analysis of the platypus reveals unique signatures of evolution , 2008, Nature.

[26]  Xuesong Lu,et al.  Predicting features of breast cancer with gene expression patterns , 2008, Breast Cancer Research and Treatment.

[27]  Jennifer A. Doudna,et al.  In vitro reconstitution of the human RISC-loading complex , 2008, Proceedings of the National Academy of Sciences.

[28]  W. Gerald,et al.  Endogenous human microRNAs that suppress breast cancer metastasis , 2008, Nature.

[29]  N. Slonim,et al.  A universal framework for regulatory element discovery across all genomes and data types. , 2007, Molecular cell.

[30]  J. Keene RNA regulons: coordination of post-transcriptional events , 2007, Nature Reviews Genetics.

[31]  G. Varani,et al.  RNA-binding proteins: modular design for efficient function , 2007, Nature Reviews Molecular Cell Biology.

[32]  G. Ayers,et al.  COX-2 involvement in breast cancer metastasis to bone , 2007, Oncogene.

[33]  T. Golub,et al.  Impaired microRNA processing enhances cellular transformation and tumorigenesis , 2007, Nature Genetics.

[34]  R. Shiekhattar,et al.  TRBP recruits the Dicer complex to Ago2 for microRNA processing and gene silencing , 2005, Nature.

[35]  Michael T. McManus,et al.  The RNaseIII enzyme Dicer is required for morphogenesis but not patterning of the vertebrate limb. , 2005, Proceedings of the National Academy of Sciences of the United States of America.

[36]  Andy J. Minn,et al.  Genes that mediate breast cancer metastasis to lung , 2005, Nature.

[37]  J. Foekens,et al.  Gene-expression profiles to predict distant metastasis of lymph-node-negative primary breast cancer , 2005, The Lancet.

[38]  J. Ikeda,et al.  Novel Nuclear Shuttle Proteins, HDBP1 and HDBP2, Bind to Neuronal Cell-specific cis-Regulatory Element in the Promoter for the Human Huntington's Disease Gene* , 2004, Journal of Biological Chemistry.

[39]  Michael Zuker,et al.  Mfold web server for nucleic acid folding and hybridization prediction , 2003, Nucleic Acids Res..

[40]  A. Thomson,et al.  mRNA Stability and the Control of Gene Expression: Implications for Human Disease , 2002, Neurochemical Research.

[41]  S. Eddy Computational Genomics of Noncoding RNA Genes , 2002, Cell.

[42]  S. Peltz,et al.  The cap-to-tail guide to mRNA turnover , 2001, Nature Reviews Molecular Cell Biology.

[43]  Walter Fontana,et al.  Fast folding and comparison of RNA secondary structures , 1994 .

[44]  K. Jeang,et al.  Relatedness of an RNA-binding motif in human immunodeficiency virus type 1 TAR RNA-binding protein TRBP to human P1/dsI kinase and Drosophila staufen , 1993, Molecular and cellular biology.

[45]  R. Strieter,et al.  Interleukin-8. A corneal factor that induces neovascularization. , 1992, The American journal of pathology.

[46]  B. Berkhout,et al.  Characterization of a human TAR RNA-binding protein that activates the HIV-1 LTR. , 1991, Science.

[47]  Michael Zuker,et al.  Optimal computer folding of large RNA sequences using thermodynamics and auxiliary information , 1981, Nucleic Acids Res..

[48]  K. Cutroneo,et al.  Silencing or knocking out eukaryotic gene expression by oligodeoxynucleotide decoys. , 2006, Critical reviews in eukaryotic gene expression.