Molecular imaging of cancer: MR spectroscopy and beyond.

[1]  T. Helbich,et al.  Diffusion-weighted MR for differentiation of breast lesions at 3.0 T: how does selection of diffusion protocols affect diagnosis? , 2009, Radiology.

[2]  Wolfgang Bogner,et al.  A Combined High Temporal and High Spatial Resolution 3 Tesla MR Imaging Protocol for the Assessment of Breast Lesions: Initial Results , 2009, Investigative radiology.

[3]  Katarzyna J Macura,et al.  Prostate cancer: sextant localization at MR imaging and MR spectroscopic imaging before prostatectomy--results of ACRIN prospective multi-institutional clinicopathologic study. , 2009, Radiology.

[4]  P. Aspelin,et al.  Diffusion-weighted magnetic resonance imaging of pancreas tumours , 2009, European Radiology.

[5]  L. Turnbull Dynamic contrast‐enhanced MRI in the diagnosis and management of breast cancer , 2009, NMR in biomedicine.

[6]  Daniel B. Vigneron,et al.  Advances in MR spectroscopy of the prostate. , 2008, Magnetic resonance imaging clinics of North America.

[7]  C. Mountford,et al.  Evaluation of Ovarian Tumors by Proton Magnetic Resonance Spectroscopy at Three Tesla , 2008, Investigative radiology.

[8]  John V Frangioni,et al.  New technologies for human cancer imaging. , 2008, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[9]  Christopher Nimsky,et al.  Metabolic Imaging of Cerebral Gliomas: Spatial Correlation of Changes in O-(2-18F-Fluoroethyl)-l-Tyrosine PET and Proton Magnetic Resonance Spectroscopic Imaging , 2008, Journal of Nuclear Medicine.

[10]  M. Tozaki Proton MR spectroscopy of the breast , 2008, Breast cancer.

[11]  A. Fausto,et al.  MR spectroscopy of the breast , 2008, La radiologia medica.

[12]  H. Hricak,et al.  Prostate cancer imaging , 2008, Acta radiologica.

[13]  K. Togashi,et al.  The utility of diffusion-weighted MR imaging for differentiating uterine sarcomas from benign leiomyomas , 2007, European Radiology.

[14]  R. Ouwerkerk Sodium magnetic resonance imaging: from research to clinical use. , 2007, Journal of the American College of Radiology : JACR.

[15]  Wei Huang,et al.  Proton (1H) MR spectroscopy of the breast. , 2007, Radiographics : a review publication of the Radiological Society of North America, Inc.

[16]  Wei Huang,et al.  Enhancing nonmass lesions in the breast: evaluation with proton (1H) MR spectroscopy. , 2007, Radiology.

[17]  C. Kuhl Current status of breast MR imaging. Part 2. Clinical applications. , 2007, Radiology.

[18]  K. Togashi,et al.  Diffusion‐weighted MR imaging of uterine endometrial cancer , 2007, Journal of magnetic resonance imaging : JMRI.

[19]  C. Kuhl Breast MR imaging at 3T. , 2007, Magnetic resonance imaging clinics of North America.

[20]  C. Kuhl The current status of breast MR imaging. Part I. Choice of technique, image interpretation, diagnostic accuracy, and transfer to clinical practice. , 2007, Radiology.

[21]  D. Collins,et al.  Diffusion-weighted MRI in the body: applications and challenges in oncology. , 2007, AJR. American journal of roentgenology.

[22]  Peter L Choyke,et al.  Imaging prostate cancer: a multidisciplinary perspective. , 2007, Radiology.

[23]  C. Nimsky,et al.  Proton Magnetic Resonance Spectroscopic Imaging in the Border Zone of Gliomas: Correlation of Metabolic and Histological Changes at Low Tumor Infiltration—Initial Results , 2007, Investigative radiology.

[24]  A. Cilotti,et al.  Quantitative diffusion-weighted MR imaging in the differential diagnosis of breast lesion , 2007, European Radiology.

[25]  Paul A. Bottomley,et al.  Elevated tissue sodium concentration in malignant breast lesions detected with non-invasive 23Na MRI , 2007, Breast Cancer Research and Treatment.

[26]  Frederik De Keyzer,et al.  Extracranial applications of diffusion-weighted magnetic resonance imaging , 2007, European Radiology.

[27]  Mauricio Castillo,et al.  Clinical role of proton magnetic resonance spectroscopy in oncology: brain, breast, and prostate cancer. , 2006, The Lancet. Oncology.

[28]  Elias R Melhem,et al.  Advanced MR imaging techniques in the diagnosis of intraaxial brain tumors in adults. , 2006, Radiographics : a review publication of the Radiological Society of North America, Inc.

[29]  Sukru Mehmet Erturk,et al.  High-B-value diffusion-weighted MRI in colorectal cancer. , 2006, AJR. American journal of roentgenology.

[30]  Wei Huang,et al.  Proton MR spectroscopy with choline peak as malignancy marker improves positive predictive value for breast cancer diagnosis: preliminary study. , 2006, Radiology.

[31]  J. Schramm,et al.  Low-Grade Gliomas - Current Concepts , 2006, Zentralblatt fur Neurochirurgie.

[32]  Susan M. Chang,et al.  Diagnosis and treatment of recurrent high-grade astrocytoma. , 2006, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[33]  Christopher Nimsky,et al.  Preoperative grading of gliomas by using metabolite quantification with high-spatial-resolution proton MR spectroscopic imaging. , 2006, Radiology.

[34]  L. Turnbull,et al.  Diffusion Imaging of the Prostate at 3.0 Tesla , 2006, Investigative radiology.

[35]  L. Turnbull,et al.  Diffusion‐weighted imaging of normal and malignant prostate tissue at 3.0T , 2006, Journal of magnetic resonance imaging : JMRI.

[36]  M. Lesniak,et al.  Surgical management of high-grade gliomas , 2005, Expert review of neurotherapeutics.

[37]  Hans H Schild,et al.  Dynamic bilateral contrast-enhanced MR imaging of the breast: trade-off between spatial and temporal resolution. , 2005, Radiology.

[38]  Masahiko Watanabe,et al.  Diffusion-Weighted Imaging of Malignant Breast Tumors: The Usefulness of Apparent Diffusion Coefficient (ADC) Value and ADC Map for the Detection of Malignant Breast Tumors and Evaluation of Cancer Extension , 2005, Journal of computer assisted tomography.

[39]  K. Brandt,et al.  Adding in vivo quantitative 1H MR spectroscopy to improve diagnostic accuracy of breast MR imaging: preliminary results of observer performance study at 4.0 T. , 2005, Radiology.

[40]  Takeo Ishigaki,et al.  Diffusion‐weighted images of the liver: Comparison of tumor detection before and after contrast enhancement with superparamagnetic iron oxide , 2005, Journal of magnetic resonance imaging : JMRI.

[41]  D. Yeung,et al.  In vivo 1H MR spectroscopy of thyroid carcinoma. , 2005, European journal of radiology.

[42]  Christopher Nimsky,et al.  Proton Magnetic Resonance Spectroscopic Imaging Integrated into Image-guided Surgery: Correlation to Standard Magnetic Resonance Imaging and Tumor Cell Density , 2005, Neurosurgery.

[43]  Takeo Ishigaki,et al.  Differentiation of noncancerous tissue and cancer lesions by apparent diffusion coefficient values in transition and peripheral zones of the prostate , 2005, Journal of magnetic resonance imaging : JMRI.

[44]  M. Kattan,et al.  Correlation of proton MR spectroscopic imaging with gleason score based on step-section pathologic analysis after radical prostatectomy. , 2005, Radiology.

[45]  P. Carroll,et al.  Prostate depiction at endorectal MR spectroscopic imaging: investigation of a standardized evaluation system. , 2004, Radiology.

[46]  D. Yee,et al.  Neoadjuvant chemotherapy of locally advanced breast cancer: predicting response with in vivo (1)H MR spectroscopy--a pilot study at 4 T. , 2004, Radiology.

[47]  J. Kurhanewicz,et al.  Endorectal MR imaging and MR spectroscopic imaging for locally recurrent prostate cancer after external beam radiation therapy: preliminary experience. , 2004, Radiology.

[48]  C. Nimsky,et al.  Improved delineation of brain tumors: an automated method for segmentation based on pathologic changes of 1H-MRSI metabolites in gliomas , 2004, NeuroImage.

[49]  T. Brown,et al.  Methodological standardization for a multi‐institutional in vivo trial of localized 31P MR spectroscopy in human cancer research. In vitro and normal volunteer studies , 2004, NMR in biomedicine.

[50]  K. Hosseinzadeh,et al.  Endorectal diffusion‐weighted imaging in prostate cancer to differentiate malignant and benign peripheral zone tissue , 2004, Journal of magnetic resonance imaging : JMRI.

[51]  Christopher Nimsky,et al.  Integration of biochemical images of a tumor into frameless stereotaxy achieved using a magnetic resonance imaging/magnetic resonance spectroscopy hybrid data set. , 2004, Journal of neurosurgery.

[52]  I. Cox,et al.  Preinvasive and invasive cervical cancer: an ex vivo proton magic angle spinning magnetic resonance spectroscopy study , 2004, NMR in biomedicine.

[53]  T. Brown,et al.  Predicting treatment response in non-Hodgkin's lymphoma from the pretreatment tumor content of phosphoethanolamine plus phosphocholine. , 2004, Academic radiology.

[54]  G. Shah,et al.  Magnetic Resonance Spectroscopy of Head and Neck Neoplasms , 2004, Topics in magnetic resonance imaging : TMRI.

[55]  I. Cox,et al.  1H magnetic resonance spectroscopy of preinvasive and invasive cervical cancer: In vivo–ex vivo profiles and effect of tumor load , 2004, Journal of magnetic resonance imaging : JMRI.

[56]  D. Yeung,et al.  In vivo proton MR spectroscopy of primary and nodal nasopharyngeal carcinoma. , 2004, AJNR. American journal of neuroradiology.

[57]  A. Häkkinen,et al.  Low-grade gliomas and focal cortical developmental malformations: differentiation with proton MR spectroscopy. , 2004, Radiology.

[58]  I. Cox,et al.  1H magnetic resonance spectroscopy of invasive cervical cancer: an in vivo study with ex vivo corroboration , 2004, NMR in biomedicine.

[59]  Glyn Johnson,et al.  Glioma grading: sensitivity, specificity, and predictive values of perfusion MR imaging and proton MR spectroscopic imaging compared with conventional MR imaging. , 2003, AJNR. American journal of neuroradiology.

[60]  Winnie C W Chu,et al.  Characterization of lesions of the breast with proton MR spectroscopy: comparison of carcinomas, benign lesions, and phyllodes tumors. , 2003, AJR. American journal of roentgenology.

[61]  Franklyn A Howe,et al.  1H MR spectroscopy of brain tumours and masses , 2003, NMR in biomedicine.

[62]  Paul A Bottomley,et al.  Tissue sodium concentration in human brain tumors as measured with 23Na MR imaging. , 2003, Radiology.

[63]  Carles Arús,et al.  Proton magnetic resonance spectroscopy (1H MRS) of human brain tumours: assessment of differences between tumour types and its applicability in brain tumour categorization , 2003, European Radiology.

[64]  V. L. Doyle,et al.  Metabolic profiles of human brain tumors using quantitative in vivo 1H magnetic resonance spectroscopy , 2003, Magnetic resonance in medicine.

[65]  Damien Galanaud,et al.  Use of proton magnetic resonance spectroscopy of the brain to differentiate gliomatosis cerebri from low-grade glioma. , 2003, Journal of neurosurgery.

[66]  Carles Arús,et al.  Automated classification of short echo time in in vivo 1H brain tumor spectra: A multicenter study , 2003, Magnetic resonance in medicine.

[67]  M. Kitajima,et al.  Cerebral gliomas: prospective comparison of multivoxel 2D chemical-shift imaging proton MR spectroscopy, echoplanar perfusion and diffusion-weighted MRI , 2002, Neuroradiology.

[68]  Roland G Henry,et al.  Characterization of untreated gliomas by magnetic resonance spectroscopic imaging. , 2002, Neuroimaging clinics of North America.

[69]  Carles Arús,et al.  Adult primitive neuroectodermal tumor: proton MR spectroscopic findings with possible application for differential diagnosis. , 2002, Radiology.

[70]  Ning-Yu An,et al.  Differentiation of clinically benign and malignant breast lesions using diffusion‐weighted imaging , 2002, Journal of magnetic resonance imaging : JMRI.

[71]  L. Liberman,et al.  Breast lesions detected on MR imaging: features and positive predictive value. , 2002, AJR. American journal of roentgenology.

[72]  Mark Rijpkema,et al.  Prediction of treatment response of head and neck cancers with P-31 MR spectroscopy from pretreatment relative phosphomonoester levels. , 2002, Academic radiology.

[73]  L. Esserman,et al.  Magnetic resonance imaging for primary breast cancer management: current role and new applications. , 2002, Endocrine-related cancer.

[74]  Mauricio Castillo,et al.  Clinical Applications of Proton MR Spectroscopy in Oncology , 2002, Technology in cancer research & treatment.

[75]  V. Stieber Low-grade gliomas , 2001, Current Treatment Options in Oncology.

[76]  T. Mikkelsen,et al.  Correlation between Magnetic Resonance Spectroscopy Imaging and Image-guided Biopsies: Semiquantitative and Qualitative Histopathological Analyses of Patients with Untreated Glioma , 2001, Neurosurgery.

[77]  Robert E. Lenkinski,et al.  The evaluation of human breast lesions with magnetic resonance imaging and proton magnetic resonance spectroscopy , 2001, Breast Cancer Research and Treatment.

[78]  D. Yeung,et al.  Human breast lesions: characterization with contrast-enhanced in vivo proton MR spectroscopy--initial results. , 2001, Radiology.

[79]  J. Nelson,et al.  Detection of increased choline compounds with proton nuclear magnetic resonance spectroscopy subsequent to malignant transformation of human prostatic epithelial cells. , 2001, Cancer research.

[80]  S. Dwivedi,et al.  Evaluation of total choline from in-vivo volume localized proton MR spectroscopy and its response to neoadjuvant chemotherapy in locally advanced breast cancer , 2001, British Journal of Cancer.

[81]  G. Kemp,et al.  Non-Invasive Methods for Studying Brain Energy Metabolism: What They Show and What It Means , 2000, Developmental Neuroscience.

[82]  E A Sickles,et al.  Dynamic high-spatial-resolution MR imaging of suspicious breast lesions: diagnostic criteria and interobserver variability. , 2000, AJR. American journal of roentgenology.

[83]  T. Helbich,et al.  Contrast-enhanced magnetic resonance imaging of the breast. , 2000, European journal of radiology.

[84]  P. Carroll,et al.  Prostate cancer: localization with three-dimensional proton MR spectroscopic imaging--clinicopathologic study. , 1999, Radiology.

[85]  F. Podo Tumour phospholipid metabolism , 1999, NMR in biomedicine.

[86]  I. Gribbestad,et al.  Characterization of neoplastic and normal human breast tissues with in vivo 1H MR spectroscopy , 1999, Journal of magnetic resonance imaging : JMRI.

[87]  T. Parrish,et al.  Relationship of elevated 23Na magnetic resonance image intensity to infarct size after acute reperfused myocardial infarction. , 1999, Circulation.

[88]  M. Castillo,et al.  Clinical applications of proton magnetic resonance spectroscopy in the evaluation of common intracranial tumors. , 1999, Topics in magnetic resonance imaging : TMRI.

[89]  M. Castillo,et al.  Proton MR spectroscopy of common brain tumors. , 1998, Neuroimaging clinics of North America.

[90]  R. Lenkinski,et al.  Human breast lesions: characterization with proton MR spectroscopy. , 1998, Radiology.

[91]  Anna L. Brown,et al.  Effect of preoperative chemotherapy on the outcome of women with operable breast cancer. , 1998, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[92]  Stephen Ashwal,et al.  Proton Magnetic Resonance Spectroscopy: An Emerging Technology in Pediatric Neurology Research , 1998, Pediatric Research.

[93]  J. H. Lee,et al.  Localized in vivo 1H nuclear MR spectroscopy for evaluation of human uterine cervical carcinoma. , 1998, AJR. American journal of roentgenology.

[94]  Susan M. Chang,et al.  Serial proton magnetic resonance spectroscopy imaging of glioblastoma multiforme after brachytherapy. , 1997, Journal of neurosurgery.

[95]  N. Lundbom,et al.  Increased choline signal coinciding with malignant degeneration of cerebral gliomas: a serial proton magnetic resonance spectroscopy imaging study. , 1997, Journal of Neurosurgery.

[96]  K. Muller,et al.  Proton MR spectroscopy of squamous cell carcinoma of the extracranial head and neck: in vitro and in vivo studies. , 1997, AJNR. American journal of neuroradiology.

[97]  S B Reeder,et al.  Fast 23Na magnetic resonance imaging of acute reperfused myocardial infarction. Potential to assess myocardial viability. , 1997, Circulation.

[98]  P. Carroll,et al.  Focal therapy for prostate cancer 1996: maximizing outcome. , 1997, Urology.

[99]  A Heinig,et al.  Contrast-enhanced MRI of the breast: accuracy, value, controversies, solutions. , 1997, European journal of radiology.

[100]  R. Kim,et al.  Myocardial Gd-DTPA kinetics determine MRI contrast enhancement and reflect the extent and severity of myocardial injury after acute reperfused infarction. , 1996, Circulation.

[101]  M. Castillo,et al.  Proton MR spectroscopy of squamous cell carcinoma of the upper aerodigestive tract: in vitro characteristics. , 1996, AJNR. American journal of neuroradiology.

[102]  T R Brown,et al.  Proton magnetic resonance spectroscopy in patients with glial tumors: a multicenter study. , 1996, Journal of neurosurgery.

[103]  P. Carroll,et al.  Three-dimensional H-1 MR spectroscopic imaging of the in situ human prostate with high (0.24-0.7-cm3) spatial resolution. , 1996, Radiology.

[104]  B. Asselain,et al.  Breast tumour response to primary chemotherapy predicts local and distant control as well as survival. , 1995, European journal of cancer.

[105]  T E Conturo,et al.  Diffusion MRI: Precision, accuracy and flow effects , 1995, NMR in biomedicine.

[106]  D. Ballon,et al.  In vitro and in vivo 31P nuclear magnetic resonance measurements of metabolic changes post radiation. , 1995, Cancer research.

[107]  J G Pipe,et al.  In vivo MR determination of water diffusion coefficients and diffusion anisotropy: correlation with structural alteration in gliomas of the cerebral hemispheres. , 1995, AJNR. American journal of neuroradiology.

[108]  P. Viehweg,et al.  Sensitivity of contrast-enhanced MR imaging of the breast. , 1994, Magnetic resonance imaging clinics of North America.

[109]  H. Thaler,et al.  Radiation dose-dependent changes in tumor metabolism measured by 31P nuclear magnetic resonance spectroscopy. , 1994, Cancer research.

[110]  R D Tien,et al.  MR imaging of high-grade cerebral gliomas: value of diffusion-weighted echoplanar pulse sequences. , 1994, AJR. American journal of roentgenology.

[111]  C. Mountford,et al.  Proton MR and human cervical neoplasia: ex vivo spectroscopy allows distinction of invasive carcinoma of the cervix from carcinoma in situ and other preinvasive lesions. , 1993, Radiology.

[112]  J. Frahm,et al.  Absolute concentrations of metabolites in the adult human brain in vivo: quantification of localized proton MR spectra. , 1993, Radiology.

[113]  D. Gadian,et al.  Proton nuclear magnetic resonance spectroscopy unambiguously identifies different neural cell types , 1993, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[114]  J Hennig,et al.  Human brain tumors: assessment with in vivo proton MR spectroscopy. , 1993, Radiology.

[115]  H. Degani,et al.  Phosphate metabolites and steroid hormone receptors of benign and malignant breast tumors. A nuclear magnetic resonance study , 1991, Cancer.

[116]  B. Rajagopalan,et al.  Abnormal phosphomonoester signals in 31P MR spectra from patients with hepatic lymphoma. A possible marker of liver infiltration and response to chemotherapy. , 1991, British Journal of Cancer.

[117]  B. Miller A review of chemical issues in 1H NMR spectroscopy: N‐acetyl‐l‐aspartate, creatine and choline , 1991, NMR in biomedicine.

[118]  J A Frank,et al.  Metabolism of human gliomas: assessment with H-1 MR spectroscopy and F-18 fluorodeoxyglucose PET. , 1990, Radiology.

[119]  P. V. van Zijl,et al.  Proton magnetic resonance spectroscopy of small regions (1 mL) localized inside superficial human tumors. A clinical feasibility study , 1990, NMR in biomedicine.

[120]  J. Frahm,et al.  Localized proton NMR spectroscopy in different regions of the human brain in vivo. Relaxation times and concentrations of cerebral metabolites , 1989, Magnetic resonance in medicine.

[121]  W. Kaiser,et al.  MR imaging of the breast: fast imaging sequences with and without Gd-DTPA. Preliminary observations. , 1989, Radiology.

[122]  S. Green,et al.  Glioblastoma multiforme and anaplastic astrocytoma pathologic criteria and prognostic implications , 1985, Cancer.

[123]  I. Nagy,et al.  Correlation of malignancy with the intracellular Na+:K+ ratio in human thyroid tumors. , 1983, Cancer research.

[124]  I. Cameron,et al.  Intracellular concentration of sodium and other elements as related to mitogenesis and oncogenesis in vivo. , 1980, Cancer research.

[125]  E. R. Andrew,et al.  Nuclear Magnetic Resonance , 1955 .

[126]  M. Vendrell Enhancing Nonmass Lesions in the Breast: Evaluation with Proton (1H) MR Spectroscopy: Bartella L, Thakur SB, Morris EA, et al (Memorial Sloan-Kettering Cancer Ctr, New York, NY) Radiology 245:80-87, 2007§ , 2009 .

[127]  H. Hricak,et al.  Imaging of prostate cancer. , 2007, Radiologic clinics of North America.

[128]  Thomas E Yankeelov,et al.  Integration of quantitative DCE-MRI and ADC mapping to monitor treatment response in human breast cancer: initial results. , 2007, Magnetic resonance imaging.

[129]  L. Liberman,et al.  Imaging breast cancer. , 2007, Radiologic clinics of North America.

[130]  P. Carroll,et al.  Magnetic resonance imaging and spectroscopy of prostate cancer. , 2006, Reviews in urology.

[131]  Elizabeth A. Morris,et al.  Advances in breast imaging: Magnetic resonance imaging , 2006, Current oncology reports.

[132]  Ewald Moser,et al.  Proton magnetic resonance spectroscopic imaging in brain tumor diagnosis. , 2005, Neurosurgery clinics of North America.

[133]  Masanori Ozaki,et al.  ADC mapping of benign and malignant breast tumors. , 2005, Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine.

[134]  Thomas Dierks,et al.  Determination of histopathological tumor grade in neuroepithelial brain tumors by using spectral pattern analysis of in vivo spectroscopic data. , 2003, Journal of neurosurgery.

[135]  Edward Pan,et al.  Glioblastoma Multiforme and Anaplastic Astrocytoma , 2003 .

[136]  E. Adalsteinsson,et al.  In vivo 1H MR spectroscopy of human head and neck lymph node metastasis and comparison with oxygen tension measurements. , 2000, AJNR. American journal of neuroradiology.

[137]  H. Hricak,et al.  The prostate: MR imaging and spectroscopy. Present and future. , 2000, Radiologic clinics of North America.

[138]  M. Castillo,et al.  Clinical applications of proton MR spectroscopy. , 1996, AJNR. American journal of neuroradiology.

[139]  M Hoehn-Berlage,et al.  Quantitative diffusion MR imaging of cerebral tumor and edema. , 1994, Acta neurochirurgica. Supplementum.

[140]  M. Dewhirst,et al.  MR imaging and spectroscopy for prognostic evaluation in soft-tissue sarcomas. , 1994, Radiology.