Dissection of pyroptosis-related prognostic signature and CASP6-mediated regulation in pancreatic adenocarcinoma: new sights to clinical decision-making

[1]  Yunpeng Shi,et al.  CASP6 predicts poor prognosis in glioma and correlates with tumor immune microenvironment , 2022, Frontiers in Oncology.

[2]  E. Giovannetti,et al.  Novel Strategies to Address Critical Challenges in Pancreatic Cancer , 2022, Cancers.

[3]  Hao Wang,et al.  Pyroptosis-Related Signature as Potential Biomarkers for Predicting Prognosis and Therapy Response in Colorectal Cancer Patients , 2022, Frontiers in Genetics.

[4]  Guo Huang,et al.  Identification of pyroptosis related subtypes and tumor microenvironment infiltration characteristics in breast cancer , 2022, Scientific Reports.

[5]  Lei Wang,et al.  The role of pyroptosis in modulating the tumor immune microenvironment , 2022, Biomarker research.

[6]  Guo-ping Ding,et al.  A pyroptosis-related gene signature predicts prognosis and immune microenvironment in hepatocellular carcinoma , 2022, World Journal of Surgical Oncology.

[7]  Y. Zhang,et al.  A panel of necroptosis-related genes predicts the prognosis of pancreatic adenocarcinoma , 2022, Translational oncology.

[8]  F. Moreau,et al.  The colonic pathogen Entamoeba histolytica activates caspase-4/1 that cleaves the pore-forming protein gasdermin D to regulate IL-1β secretion , 2022, PLoS pathogens.

[9]  Chenxi Liu,et al.  Prognosis and survival analysis of patients with pancreatic cancer: retrospective experience of a single institution , 2022, World Journal of Surgical Oncology.

[10]  F. Scaldaferri,et al.  Novel Insights Into the Interactions Between the Gut Microbiome, Inflammasomes, and Gasdermins During Colorectal Cancer , 2022, Frontiers in Cellular and Infection Microbiology.

[11]  Á. Camarena,et al.  Old and New Players of Inflammation and Their Relationship With Cancer Development , 2021, Frontiers in Oncology.

[12]  S. Jiang,et al.  A Novel Pyroptosis-related Prognostic Model for Hepatocellular Carcinoma , 2021, Frontiers in Cell and Developmental Biology.

[13]  Shelly C. Lu,et al.  Incidence of Pancreatic Cancer by Age and Sex in the US, 2000-2018. , 2021, JAMA.

[14]  A. Singh,et al.  Current and emerging therapeutic strategies in pancreatic cancer: Challenges and opportunities , 2021, World journal of gastroenterology.

[15]  Youbin Liu,et al.  LncRNA PVT1 Knockdown Ameliorates Myocardial Ischemia Reperfusion Damage via Suppressing Gasdermin D-Mediated Pyroptosis in Cardiomyocytes , 2021, Frontiers in Cardiovascular Medicine.

[16]  S. Shalapour,et al.  Regulation of antitumor immunity by inflammation-induced epigenetic alterations , 2021, Cellular & molecular immunology.

[17]  Bomeng Wu,et al.  Identification of the pyroptosis‑related prognostic gene signature and the associated regulation axis in lung adenocarcinoma , 2021, Cell Death Discovery.

[18]  Xiaohu Wu,et al.  LPS Mediates Bovine Endometrial Epithelial Cell Pyroptosis Directly Through Both NLRP3 Classical and Non-Classical Inflammasome Pathways , 2021, Frontiers in Immunology.

[19]  Dawang Zhou,et al.  The metabolite α-KG induces GSDMC-dependent pyroptosis through death receptor 6-activated caspase-8 , 2021, Cell Research.

[20]  Shuohua Chen,et al.  Pyroptosis-Related Gene Signatures Can Robustly Diagnose Skin Cutaneous Melanoma and Predict the Prognosis , 2021, bioRxiv.

[21]  Min Gao,et al.  lncRNA PVT1 modulates NLRP3‑mediated pyroptosis in septic acute kidney injury by targeting miR‑20a‑5p. , 2021, Molecular medicine reports.

[22]  C. Iacobuzio-Donahue,et al.  Pancreatic cancer prognosis is predicted by an ATAC-array technology for assessing chromatin accessibility , 2021, Nature Communications.

[23]  Wei Zhang,et al.  Caspase 4 Overexpression as a Prognostic Marker in Clear Cell Renal Cell Carcinoma: A Study Based on the Cancer Genome Atlas Data Mining , 2021, Frontiers in Genetics.

[24]  M. O'Hara,et al.  Challenges and Opportunities for Pancreatic Cancer Immunotherapy. , 2020, Cancer cell.

[25]  J. Tainer,et al.  PD-L1-Mediated Gasdermin C Expression Switches Apoptosis to Pyroptosis in Cancer Cells and Facilitates Tumor Necrosis , 2020, Nature Cell Biology.

[26]  Shiqi Yang,et al.  Pyroptosis: a pro-inflammatory type of cell death in cardiovascular disease. , 2020, Clinica chimica acta; international journal of clinical chemistry.

[27]  R. Croner,et al.  Advanced Pancreatic Ductal Adenocarcinoma: Moving Forward , 2020, Cancers.

[28]  D. V. Hoff,et al.  Extracellular Vesicles in Diagnosis and Treatment of Pancreatic Cancer: Current State and Future Perspectives , 2020, Cancers.

[29]  Ming Lu,et al.  Kynurenine regulates NLRP2 inflammasome in astrocytes and its implications in depression , 2020, Brain, Behavior, and Immunity.

[30]  P. Vogel,et al.  Caspase-6 Is a Key Regulator of Innate Immunity, Inflammasome Activation, and Host Defense , 2020, Cell.

[31]  Yan Li,et al.  Development of an autophagy-related signature in pancreatic adenocarcinoma. , 2020, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

[32]  B. Zhang,et al.  m6A regulator-mediated methylation modification patterns and tumor microenvironment infiltration characterization in gastric cancer , 2020, Molecular Cancer.

[33]  B. Dai,et al.  Identification and validation of dichotomous immune subtypes based on intratumoral immune cells infiltration in clear cell renal cell carcinoma patients , 2020, Journal for ImmunoTherapy of Cancer.

[34]  junwei sun,et al.  Upregulation of LncRNA PVT1 Facilitates Pancreatic Ductal Adenocarcinoma Cell Progression and Glycolysis by Regulating MiR-519d-3p and HIF-1A , 2020, Journal of Cancer.

[35]  G. Zhu,et al.  Six-gene signature for predicting survival in patients with head and neck squamous cell carcinoma , 2020, Aging.

[36]  X. Xia,et al.  Emerging insights into molecular mechanisms underlying pyroptosis and functions of inflammasomes in diseases , 2019, Journal of cellular physiology.

[37]  P. Bousso,et al.  Tumor Immunosurveillance and Immunotherapies: A Fresh Look from Intravital Imaging. , 2019, Trends in immunology.

[38]  C. Liang,et al.  Age, height, BMI and FBG predict prostate volume in ageing benign prostatic hyperplasia: Evidence from 5285 patients , 2019, International journal of clinical practice.

[39]  L. Lei,et al.  The role of pyroptosis in cancer: pro-cancer or pro-“host”? , 2019, Cell Death & Disease.

[40]  Peifeng Li,et al.  The Multifaceted Roles of Pyroptotic Cell Death Pathways in Cancer , 2019, Cancers.

[41]  T. Kanneganti,et al.  Diverging inflammasome signals in tumorigenesis and potential targeting , 2019, Nature Reviews Cancer.

[42]  Haichao Wang,et al.  Lipid Peroxidation Drives Gasdermin D-Mediated Pyroptosis in Lethal Polymicrobial Sepsis. , 2018, Cell host & microbe.

[43]  H. Okamura,et al.  Effect of IL-18 on the Expansion and Phenotype of Human Natural Killer Cells: Application to Cancer Immunotherapy , 2018, International journal of biological sciences.

[44]  Se-Jin Yoon,et al.  MLKL, the Protein that Mediates Necroptosis, Also Regulates Endosomal Trafficking and Extracellular Vesicle Generation , 2017, Immunity.