3,4-Methylenedioxymethamphetamine (MDMA) neurotoxicity in rats: a reappraisal of past and present findings
暂无分享,去创建一个
[1] The contribution of drug research to investigating the nature of endogenous depression. , 1976, Pharmakopsychiatrie, Neuro-Psychopharmakologie.
[2] M. Gobbi,et al. Carrier‐dependent and Ca2+‐dependent 5‐HT and dopamine release induced by (+)‐amphetamine, 3,4‐methylendioxy‐methamphetamine, p‐chloroamphetamine and (+)‐fenfluramine , 1997, British journal of pharmacology.
[3] W. Slikker,et al. Behavioral and neurochemical effects of orally administered MDMA in the rodent and nonhuman primate. , 1989, Neurotoxicology.
[4] R. Roth,et al. MDMA (3,4-methylenedioxymethamphetamine) inhibits the firing of dorsal raphe neurons in brain slices via release of serotonin. , 1989, European journal of pharmacology.
[5] G. Aghajanian,et al. Serotonergic and non-serotonergic neurons of the dorsal raphe: reciprocal changes in firing induced by peripheral nerve stimulation , 1978, Brain Research.
[6] C. J. Schmidt,et al. Neurotoxicity of the psychedelic amphetamine, methylenedioxymethamphetamine. , 1987, The Journal of pharmacology and experimental therapeutics.
[7] T. Monks,et al. Serotonergic neurotoxicity of 3,4-(+/-)-methylenedioxyamphetamine and 3,4-(+/-)-methylendioxymethamphetamine (ecstasy) is potentiated by inhibition of gamma-glutamyl transpeptidase. , 2001, Chemical research in toxicology.
[8] D. E. Nichols,et al. Effects of certain hallucinogenic amphetamine analogues on the release of [3H]serotonin from rat brain synaptosomes. , 1982, Journal of medicinal chemistry.
[9] A. Cho,et al. Disposition of methylenedioxymethamphetamine and three metabolites in the brains of different rat strains and their possible roles in acute serotonin depletion. , 1996, Biochemical pharmacology.
[10] G. Battaglia,et al. MDMA-induced neurotoxicity: Parameters of degeneration and recovery of brain serotonin neurons , 1988, Pharmacology Biochemistry and Behavior.
[11] Joseph A Banken,et al. Drug Abuse Trends among Youth in the United States , 2004, Annals of the New York Academy of Sciences.
[12] R. Rothman,et al. 1-(m-Chlorophenyl)piperazine (mCPP) Dissociates In Vivo Serotonin Release from Long-Term Serotonin Depletion in Rat Brain , 2001, Neuropsychopharmacology.
[13] F. Vollenweider,et al. Which neuroreceptors mediate the subjective effects of MDMA in humans? A summary of mechanistic studies , 2001, Human psychopharmacology.
[14] A Frazer,et al. Delayed pharmacological effects of antidepressants , 2002, Molecular Psychiatry.
[15] R. Dafters. Hyperthermia following MDMA administration in rats: Effects of ambient temperature, water consumption, and chronic dosing , 1995, Physiology & Behavior.
[16] B. Yamamoto,et al. Modulation of methylenedioxymethamphetamine-induced striatal dopamine release by the interaction between serotonin and gamma-aminobutyric acid in the substantia nigra. , 1995, The Journal of pharmacology and experimental therapeutics.
[17] E. D. De Souza,et al. 3,4-Methylenedioxymethamphetamine and 3,4-methylenedioxyamphetamine destroy serotonin terminals in rat brain: quantification of neurodegeneration by measurement of [3H]paroxetine-labeled serotonin uptake sites. , 1987, The Journal of pharmacology and experimental therapeutics.
[18] J. Cadet,et al. Methylenedioxymethamphetamine (MDMA, Ecstasy) neurotoxicity: cellular and molecular mechanisms , 2003, Brain Research Reviews.
[19] D. Olton,et al. 3,4-Methylenedioxymethamphetamine, serotonin and memory. , 1993, The Journal of pharmacology and experimental therapeutics.
[20] J. O'Callaghan,et al. Mapping toxicant-induced nervous system damage with a cupric silver stain: a quantitative analysis of neural degeneration induced by 3,4-methylenedioxymethamphetamine. , 1993, NIDA research monograph.
[21] E. D. De Souza,et al. Pharmacologic profile of amphetamine derivatives at various brain recognition sites: selective effects on serotonergic systems. , 1989, NIDA research monograph.
[22] M. Colado,et al. A review of the mechanisms involved in the acute MDMA (ecstasy)-induced hyperthermic response. , 2004, European journal of pharmacology.
[23] R. Doblin. A Clinical Plan for MDMA (Ecstasy) in the Treatment of Posttraumatic Stress Disorder (PTSD): Partnering with the FDA , 2002, Journal of psychoactive drugs.
[24] B. Blough,et al. N-Substituted Piperazines Abused by Humans Mimic the Molecular Mechanism of 3,4-Methylenedioxymethamphetamine (MDMA, or ‘Ecstasy’) , 2005, Neuropsychopharmacology.
[25] L. Reneman. Designer drugs: how dangerous are they? , 2003, Journal of neural transmission. Supplementum.
[26] A. Pert,et al. Effects of 5,7‐dihydroxytryptamine depletion of tissue serotonin levels on extracellular serotonin in the striatum assessed with in vivo microdialysis: Relationship to behavior , 1999, Synapse.
[27] G. Hanson,et al. Immediate and long-term effects of 3,4-methylenedioxymethamphetamine on serotonin pathways in brain of rat , 1987, Neuropharmacology.
[28] S. Butcher,et al. Behavioural analysis of the acute and chronic effects of MDMA treatment in the rat , 1999, Psychopharmacology.
[29] R. Rothman,et al. 3,4‐methylenedioxymethamphetamine (MDMA) administration to rats decreases brain tissue serotonin but not serotonin transporter protein and glial fibrillary acidic protein , 2004, Synapse.
[30] R. Oberlender,et al. Drug discrimination studies with MDMA and amphetamine , 2004, Psychopharmacology.
[31] G. Gerra,et al. Long-lasting effects of (±)3,4-methylene-dioxymethamphetamine (Ecstasy) on serotonin system function in humans , 2000, Biological Psychiatry.
[32] G. Battaglia,et al. Methylenedioxyamphetamine (MDA) and methylenedioxymethamphetamine (MDMA) cause selective ablation of serotonergic axon terminals in forebrain: immunocytochemical evidence for neurotoxicity , 1988, The Journal of neuroscience : the official journal of the Society for Neuroscience.
[33] M. Colado,et al. The relationship between the degree of neurodegeneration of rat brain 5-HT nerve terminals and the dose and frequency of administration of MDMA (`ecstasy') , 1998, Neuropharmacology.
[34] L. Matuszewich,et al. Altered forebrain neurotransmitter responses to immobilization stress following 3,4-methylenedioxymethamphetamine , 2002, Neuroscience.
[35] F. Vollenweider,et al. Acute Psychological Effects of 3,4-Methylenedioxymethamphetamine (MDMA, “Ecstasy”) are Attenuated by the Serotonin Uptake Inhibitor Citalopram , 1999, Neuropsychopharmacology.
[36] G. Gudelsky,et al. Carrier‐Mediated Release of Serotonin by 3,4‐Methylenedioxymethamphetamine: Implications for Serotonin‐Dopamine Interactions , 1996, Journal of neurochemistry.
[37] L S Seiden,et al. Biochemical and histological evidence that methylenedioxymethylamphetamine (MDMA) is toxic to neurons in the rat brain. , 1987, The Journal of pharmacology and experimental therapeutics.
[38] T. Robinson,et al. Effects of Cortical Serotonin Depletion Induced by 3,4-Methylenedioxymethamphetamine (MDMA) on Behavior, Before and After Additional Cholinergic Blockade , 1993, Neuropsychopharmacology.
[39] E. Meririnne,et al. The Acute Effects of Amphetamine Derivatives on Extracellular Serotonin and Dopamine Levels in Rat Nucleus Accumbens , 1998, Pharmacology Biochemistry and Behavior.
[40] D. Campbell. Extrapolation from animals to man. The integration of pharmacokinetics and pharmacodynamics. , 1996, Annals of the New York Academy of Sciences.
[41] M. Morgan,et al. Ecstasy (MDMA): a review of its possible persistent psychological effects , 2000, Psychopharmacology.
[42] G. Wakonigg,et al. Methylenedioxymethamphetamine (MDMA, ‘Ecstasy‘) Serves as a Robust Positive Reinforcer in a Rat Runway Procedure , 2003, Pharmacology.
[43] F. Vollenweider,et al. Psychological and Cardiovascular Effects and Short-Term Sequelae of MDMA (“Ecstasy”) in MDMA-Naïve Healthy Volunteers , 1998, Neuropsychopharmacology.
[44] E. Gouzoulis-Mayfrank,et al. Neuroendocrine abnormalities in recreational ecstasy (MDMA) users: is it ecstasy or cannabis? , 2002, Biological Psychiatry.
[45] K. Rice,et al. Amphetamine‐type central nervous system stimulants release norepinephrine more potently than they release dopamine and serotonin , 2001, Synapse.
[46] V. Moser. The functional observational battery in adult and developing rats. , 2000, Neurotoxicology.
[47] W. Lovenberg,et al. In vitro and in vivo neurochemical effects of methylenedioxymethamphetamine on striatal monoaminergic systems in the rat brain. , 1987, Biochemical pharmacology.
[48] I. McGregor,et al. Increased anxiety and impaired memory in rats 3 months after administration of 3,4-methylenedioxymethamphetamine ("ecstasy"). , 2001, European journal of pharmacology.
[49] M. Tancer,et al. Reinforcing, subjective, and physiological effects of MDMA in humans: a comparison with d-amphetamine and mCPP. , 2003, Drug and alcohol dependence.
[50] M. Morales,et al. (±)-3,4-Methylenedioxymethamphetamine Administration to Rats Does Not Decrease Levels of the Serotonin Transporter Protein or Alter Its Distribution between Endosomes and the Plasma Membrane , 2005, Journal of Pharmacology and Experimental Therapeutics.
[51] D. BRUCE CAMPBELL,et al. Extrapolation from Animals to Man , 1996 .
[52] R. Glennon,et al. 3,4-Methylenedioxymethamphetamine (MDMA): Stereoselective interactions at brain 5-HT1 and 5-HT2 receptors , 2004, Psychopharmacology.
[53] R. de la Torre,et al. Non-linear pharmacokinetics of MDMA ('ecstasy') in humans. , 2000, British journal of clinical pharmacology.
[54] James H Brown,et al. Allometric scaling of metabolic rate from molecules and mitochondria to cells and mammals , 2002, Proceedings of the National Academy of Sciences of the United States of America.
[55] K. Rice,et al. Neurochemical neutralization of amphetamine-type stimulants in rat brain by the indatraline analog (−)-HY038 , 2000, Brain Research Bulletin.
[56] M. Shankaran,et al. A neurotoxic regimen of MDMA suppresses behavioral, thermal and neurochemical responses to subsequent MDMA administration , 1999, Psychopharmacology.
[57] H. Steinbusch,et al. Distribution of serotonin-immunoreactivity in the central nervous system of the rat—Cell bodies and terminals , 1981, Neuroscience.
[58] Craig R. White,et al. Allometric scaling of mammalian metabolism , 2005, Journal of Experimental Biology.
[59] A Frazer,et al. Effects of Chronic Antidepressant Treatments on Serotonin Transporter Function, Density, and mRNA Level , 1999, The Journal of Neuroscience.
[60] E. Sellers,et al. Interactions of amphetamine analogs with human liver CYP2D6. , 1997, Biochemical pharmacology.
[61] K. Boone,et al. Abnormal ACTH and prolactin responses to fenfluramine in rats exposed to single and multiple doses of MDMA , 1997, Psychopharmacology.
[62] I. McGregor,et al. Increased Anxiety 3 Months after Brief Exposure to MDMA (‘Ecstasy’) in Rats: Association with Altered 5-HT Transporter and Receptor Density , 2003, Neuropsychopharmacology.
[63] A. Poling,et al. MDMA and Learning Effects of Acute and Neurotoxic Exposure in the Rat , 2000, Pharmacology Biochemistry and Behavior.
[64] L. Schmued. Demonstration and localization of neuronal degeneration in the rat forebrain following a single exposure to MDMA , 2003, Brain Research.
[65] J. O'Callaghan,et al. Comparative study of fluoxetine, sibutramine, sertraline and dexfenfluramine on the morphology of serotonergic nerve terminals using serotonin immunohistochemistry , 2000, Brain Research.
[66] M. Tancer,et al. Discriminative stimulus effects of 3,4-methylenedioxymethamphetamine (MDMA) in humans trained to discriminate among d-amphetamine, meta-chlorophenylpiperazine and placebo. , 2006, Drug and alcohol dependence.
[67] L. Kirby,et al. Effect of destruction of serotonin neurons on basal and fenfluramine‐induced serotonin release in striatum , 1995, Synapse.
[68] S. Kish. How strong is the evidence that brain serotonin neurons are damaged in human users of ecstasy? , 2002, Pharmacology Biochemistry and Behavior.
[69] J. Kelly,et al. Some behavioural and neurochemical aspects of subacute (±)3,4-methylenedioxymethamphetamine administration in rats , 1995, Pharmacology Biochemistry and Behavior.
[70] K. Fone,et al. Reduced social interaction following 3,4-methylenedioxymethamphetamine is not associated with enhanced 5-HT2C receptor responsivity , 2003, Neuropharmacology.
[71] Michelle N Lafrance. A Bitter Pill , 2007, Journal of health psychology.
[72] M. Ansseau,et al. Polymorphisms in the CYP 2D6 Gene: Association with Plasma Concentrations of Fluoxetine and Paroxetine , 2003, Therapeutic drug monitoring.
[73] K. Fone,et al. Decreased social behaviour following 3,4-methylenedioxymethamphetamine (MDMA) is accompanied by changes in 5-HT2A receptor responsivity , 2004, Neuropharmacology.
[74] M. D. Schechter. Serotonergic-dopaminergic mediation of 3,4-methylenedioxymethamphetamine (MDMA, “ecstasy”) , 1988, Pharmacology Biochemistry and Behavior.
[75] M. Geyer,et al. Stimulant and hallucinogenic behavioral profiles of 3,4-methylenedioxymethamphetamine and N-ethyl-3,4-methylenedioxyamphetamine in rats. , 1988, The Journal of pharmacology and experimental therapeutics.
[76] J. O'Callaghan,et al. Quantification of reactive gliosis as an approach to neurotoxicity assessment. , 1993, NIDA research monograph.
[77] J. O'Callaghan,et al. Quantitative aspects of drug and toxicant-induced astrogliosis , 1995, Neurochemistry International.
[78] J. Mendelson,et al. Subjective and hormonal effects of 3,4-methylenedioxymethamphetamine (MDMA) in humans , 2002, Psychopharmacology.
[79] R. Poland. Diminished corticotropin and enhanced prolactin responses to 8-hydroxy-2(DI-n-propylamino)tetralin in methylenedioxymethamphetamine pretreated rats , 1990, Neuropharmacology.
[80] G. Gerra,et al. Serotonergic function after (±)3,4‐methylene-dioxymethamphetarnine (‘Ecstasy’) in humans , 1998, International clinical psychopharmacology.
[81] B. Yamamoto,et al. Acute and subchronic effects of methylenedioxymethamphetamine [(±)MDMA] on locomotion and serotonin syndrome behavior in the rat , 1989, Pharmacology Biochemistry and Behavior.
[82] George S. Yacoubian. Tracking Ecstasy Trends in the United States with Data from Three National Drug Surveillance Systems , 2003, Journal of drug education.
[83] S. E. Gartside,et al. Behavioural and neuroendocrine responses to D-fenfluramine in rats treated with neurotoxic amphetamines , 1995, Journal of psychopharmacology.
[84] M. Ramírez,et al. Alpha-lipoic acid prevents 3,4-methylenedioxy-methamphetamine (MDMA)-induced neurotoxicity. , 1999, Neuroreport.
[85] A. Carlssen. The Contribution of Drug Research to Investigating the Nature of Endogenous Depression* , 1976 .
[86] J. O'Callaghan,et al. Glial fibrillary acidic protein and related glial proteins as biomarkers of neurotoxicity , 2005, Expert opinion on drug safety.
[87] J. Langston,et al. Orally administered MDMA causes a long-term depletion of serotonin in rat brain , 1988, Brain Research.
[88] D E Nichols,et al. An integrated hypothesis for the serotonergic axonal loss induced by 3,4-methylenedioxymethamphetamine. , 1998, Neurotoxicology.
[89] M. Colado,et al. The Pharmacology and Clinical Pharmacology of 3,4-Methylenedioxymethamphetamine (MDMA, “Ecstasy”) , 2003, Pharmacological Reviews.
[90] I Mahmood,et al. Allometric issues in drug development. , 1999, Journal of pharmaceutical sciences.
[91] P. O'cain,et al. Cardiovascular and sympathetic responses and reflex changes elicited by MDMA , 2000, Physiology & Behavior.
[92] V. Sánchez,et al. A comparative study on the acute and long‐term effects of MDMA and 3,4‐dihydroxymethamphetamine (HHMA) on brain monoamine levels after i.p. or striatal administration in mice , 2005, British journal of pharmacology.
[93] J H Lin,et al. Applications and limitations of interspecies scaling and in vitro extrapolation in pharmacokinetics. , 1998, Drug metabolism and disposition: the biological fate of chemicals.
[94] F. Artigas,et al. Basal and stimulated extracellular serotonin concentration in the brain of rats with altered serotonin uptake , 1998, Synapse.
[95] L. Kar,et al. Monoaminergic Regulation of Neuroendocrine Function and Its Modification by Cocaine , 1994, Frontiers in Neuroendocrinology.
[96] M. Colado,et al. The pharmacology of the acute hyperthermic response that follows administration of 3,4‐methylenedioxymethamphetamine (MDMA, ‘ecstasy’) to rats , 2002, British journal of pharmacology.
[97] T. Monks,et al. The Role of Metabolism in 3,4-(±)-Methylenedioxyamphetamine and 3,4-(±)-Methylenedioxymethamphetamine (Ecstasy) toxicity , 2004, Therapeutic drug monitoring.
[98] R. Rothman,et al. (MDMA) Administration to Rats Decreases Brain Tissue Serotonin but not Serotonin Transporter Protein and Glial Fibrillary Acidic Protein , 2004 .
[99] L. Seiden,et al. Small Changes in Ambient Temperature Cause Large Changes in 3,4-Methylenedioxymethamphetamine (MDMA)-Induced Serotonin Neurotoxicity and Core Body Temperature in the Rat , 1998, The Journal of Neuroscience.
[100] V. Setola,et al. 3,4-methylenedioxymethamphetamine (MDMA, "Ecstasy") induces fenfluramine-like proliferative actions on human cardiac valvular interstitial cells in vitro. , 2003, Molecular pharmacology.
[101] H. Meltzer,et al. Elevation of serum prolactin and corticosterone concentrations in the rat after the administration of 3,4-methylenedioxymethamphetamine. , 1988, The Journal of pharmacology and experimental therapeutics.
[102] J. Swettenham,et al. Long-term changes in social interaction and reward following repeated MDMA administration to adolescent rats without accompanying serotonergic neurotoxicity , 2002, Psychopharmacology.
[103] M. P. Johnson,et al. Effects of the enantiomers of MDA, MDMA and related analogues on [3H]serotonin and [3H]dopamine release from superfused rat brain slices. , 1986, European journal of pharmacology.
[104] H. Lilienthal,et al. Extrapolation from animals to humans: scientific and regulatory aspects. , 1992, Toxicology letters.
[105] M. Pallàs,et al. Different glial response to methamphetamine- and methylenedioxymethamphetamine-induced neurotoxicity , 2003, Naunyn-Schmiedeberg's Archives of Pharmacology.
[106] S. E. Gartside,et al. Acute effects of 3,4-methylenedioxymethamphetamine (MDMA) on 5-HT cell firing and release: Comparison between dorsal and median raphe 5-HT systems , 1997, Neuropharmacology.
[107] H. Sumnall,et al. The pre-clinical behavioural pharmacology of 3,4-methylenedioxymethamphetamine (MDMA) , 2003, Neuroscience & Biobehavioral Reviews.
[108] D. Campbell. Are interspecies comparisons in the toxicity of centrally acting drugs valid without brain concentrations? A commentary , 1995, Neurochemistry International.
[109] A. Parrott. Is ecstasy MDMA? A review of the proportion of ecstasy tablets containing MDMA, their dosage levels, and the changing perceptions of purity , 2004, Psychopharmacology.
[110] M. Colado,et al. Acute and long-term effects of MDMA on cerebral dopamine biochemistry and function , 2004, Psychopharmacology.
[111] G. Rudnick,et al. From synapse to vesicle: the reuptake and storage of biogenic amine neurotransmitters. , 1993, Biochimica et biophysica acta.
[112] A. Saria,et al. Reinforcing Effects of MDMA (‘Ecstasy’) in Drug-Naive and Cocaine-Trained Rats , 2001, Pharmacology.
[113] J. Docherty,et al. Investigation of the prejunctional α2‐adrenoceptor mediated actions of MDMA in rat atrium and vas deferens , 1999 .
[114] R. Switzer. Application of Silver Degeneration Stains for Neurotoxicity Testing , 2000, Toxicologic pathology.
[115] M. Hajós,et al. A 5-hydroxytryptamine lesion markedly reduces the incidence of burst-firing dorsal raphe neurones in the rat , 1996, Neuroscience Letters.
[116] M. Forsling,et al. The effect of 3,4‐methylenedioxymethamphetamine (MDMA, ?ecstasy?) and its metabolites on neurohypophysial hormone release from the isolated rat hypothalamus , 2002, British journal of pharmacology.
[117] J. Fitzgerald,et al. Interactions of methylenedioxymethamphetamine with monoamine transmitter release mechanisms in rat brain slices , 1993, Naunyn-Schmiedeberg's Archives of Pharmacology.
[118] E. Azmitia,et al. The substituted amphetamines 3,4-methylenedioxymethamphetamine, methamphetamine, p-chloroamphetamine and fenfluramine induce 5-hydroxytryptamine release via a common mechanism blocked by fluoxetine and cocaine. , 1992, European journal of pharmacology.
[119] R. Glennon,et al. Investigation of MDMA-related agents in rats trained to discriminate MDMA from saline , 1992, Pharmacology Biochemistry and Behavior.
[120] M. Kleiber. Body size and metabolism , 1932 .
[121] R. Rothman,et al. Functional Consequences of Central Serotonin Depletion Produced by Repeated Fenfluramine Administration in Rats , 1998, The Journal of Neuroscience.
[122] O. Berenfeld,et al. From Mouse to Whale: A Universal Scaling Relation for the PR Interval of the Electrocardiogram of Mammals , 2004, Circulation.
[123] M. Wilson,et al. Neurotoxicity of MDMA and Related Compounds: Anatomic Studies a , 1990, Annals of the New York Academy of Sciences.
[124] I. McGregor,et al. Increased anxiety in rats after 3,4-methylenedioxymethamphetamine: association with serotonin depletion. , 2002, European journal of pharmacology.
[125] D. Gittings,et al. Development, maintenance and temporal pattern of self-administration maintained by ecstasy (MDMA) in rats , 2003, Psychopharmacology.
[126] R. de la Torre,et al. Human pharmacology of MDMA: pharmacokinetics, metabolism, and disposition. , 2004, Therapeutic drug monitoring.
[127] A. Parrott,et al. Recreational Ecstasy/MDMA, the serotonin syndrome, and serotonergic neurotoxicity , 2002, Pharmacology Biochemistry and Behavior.
[128] A. Somogyi,et al. Acute Toxicity of 3,4-Methylenedioxymethamphetamine (MDMA) in Sprague–Dawley and Dark Agouti Rats , 1999, Pharmacology Biochemistry and Behavior.
[129] R. de la Torre,et al. Neurotoxicity of MDMA (ecstasy): the limitations of scaling from animals to humans. , 2004, Trends in pharmacological sciences.
[130] U. McCann,et al. (±)3,4-Methylenedioxymethamphetamine (‘Ecstasy’)-Induced Serotonin Neurotoxicity: Studies in Animals , 2000, Neuropsychobiology.
[131] M. Geyer. Serotonergic functions in arousal and motor activity , 1995, Behavioural Brain Research.
[132] Miller Db,et al. Quantification of reactive gliosis as an approach to neurotoxicity assessment. , 1993 .
[133] R. Rothman,et al. Therapeutic and adverse actions of serotonin transporter substrates. , 2002, Pharmacology & therapeutics.
[134] L. D. van de Kar. Neuroendocrine pharmacology of serotonergic (5-HT) neurons. , 1991, Annual review of pharmacology and toxicology.
[135] J. Fitzgerald,et al. Sympathomimetic Actions of Methylenedioxymethamphetamine in Rat and Rabbit Isolated Cardiovascular Tissues , 1994, The Journal of pharmacy and pharmacology.
[136] Fabrizio Schifano,et al. A bitter pill. Overview of ecstasy (MDMA, MDA) related fatalities , 2004, Psychopharmacology.
[137] R. Dafters,et al. Persistent loss of thermoregulation in the rat induced by 3,4-methylenedioxymethamphetamine (MDMA or “Ecstasy”) but not by fenfluramine , 1998, Psychopharmacology.
[138] P. Cowen,et al. p-Chloroamphetamine (PCA), 3,4-methylenedioxymethamphetamine (MDMA) andd-fenfluramine pretreatment attenuatesd-fenfluramine-evoked release of 5-HT in vivo , 1994, Psychopharmacology.
[139] K. Cunningham,et al. 3,4-Methylenedioxymethamphetamine (MDMA) as a unique model of serotonin receptor function and serotonin-dopamine interactions. , 2001, The Journal of pharmacology and experimental therapeutics.
[140] J. Cadet,et al. High‐dose fenfluramine administration decreases serotonin transporter binding, but not serotonin transporter protein levels, in rat forebrain , 2003, Synapse.
[141] L. Schmued,et al. Fluoro-Jade B: a high affinity fluorescent marker for the localization of neuronal degeneration , 2000, Brain Research.
[142] R. de la Torre,et al. Cardiovascular and neuroendocrine effects and pharmacokinetics of 3, 4-methylenedioxymethamphetamine in humans. , 1999, The Journal of pharmacology and experimental therapeutics.
[143] J. Docherty,et al. Investigation of the prejunctional alpha2-adrenoceptor mediated actions of MDMA in rat atrium and vas deferens. , 1999, British Journal of Pharmacology.
[144] J L Katz,et al. Serotonergic recovery after (+/-)3,4-(methylenedioxy) methamphetamine injury: observations in rats. , 1993, The Journal of pharmacology and experimental therapeutics.
[145] A. Grace,et al. Compensations after lesions of central dopaminergic neurons: some clinical and basic implications , 1990, Trends in Neurosciences.
[146] F. Peters,et al. Toxicokinetics and analytical toxicology of amphetamine-derived designer drugs ('Ecstasy'). , 2000, Toxicology letters.
[147] J. Lin,et al. Species similarities and differences in pharmacokinetics. , 1995, Drug metabolism and disposition: the biological fate of chemicals.