Regulation of gene expression by the small GTPase Rho through the ERK6 (p38γ) MAP kinase pathway
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[1] R. Tapping,et al. Role of BMK1 in regulation of growth factor-induced cellular responses , 2000, Immunologic research.
[2] Jiahuai Han,et al. Involvement of the MKK6-p38γ Cascade in γ-Radiation-Induced Cell Cycle Arrest , 2000, Molecular and Cellular Biology.
[3] H. Enslen,et al. Molecular determinants that mediate selective activation of p38 MAP kinase isoforms , 2000, The EMBO journal.
[4] J. Gutkind,et al. Multiple Mitogen-Activated Protein Kinase Signaling Pathways Connect the Cot Oncoprotein to the c-junPromoter and to Cellular Transformation , 2000, Molecular and Cellular Biology.
[5] Y. Ono,et al. Interaction of PKN with a neuron-specific basic helix-loop-helix transcription factor, NDRF/NeuroD2. , 1999, Brain research. Molecular brain research.
[6] Y. Ono,et al. Mutational analysis of the regulatory mechanism of PKN: the regulatory region of PKN contains an arachidonic acid-sensitive autoinhibitory domain. , 1999, Journal of biochemistry.
[7] Richard Treisman,et al. Signal-Regulated Activation of Serum Response Factor Is Mediated by Changes in Actin Dynamics , 1999, Cell.
[8] J. Gutkind,et al. A Network of Mitogen-Activated Protein Kinases Links G Protein-Coupled Receptors to the c-jun Promoter: a Role for c-Jun NH2-Terminal Kinase, p38s, and Extracellular Signal-Regulated Kinase 5 , 1999, Molecular and Cellular Biology.
[9] Andrew D. Sharrocks,et al. Targeting of p38 Mitogen-Activated Protein Kinases to MEF2 Transcription Factors , 1999, Molecular and Cellular Biology.
[10] P. Cohen,et al. Stress-activated protein kinase-3 interacts with the PDZ domain of alpha1-syntrophin. A mechanism for specific substrate recognition. , 1999, The Journal of biological chemistry.
[11] E. Wagner,et al. Control of cell cycle progression by c-Jun is p53 dependent. , 1999, Genes & development.
[12] R. Treisman,et al. Transformation mediated by RhoA requires activity of ROCK kinases , 1999, Current Biology.
[13] Jiahuai Han,et al. Regulation of the MEF2 Family of Transcription Factors by p38 , 1999, Molecular and Cellular Biology.
[14] Y. Ono,et al. Proteolytic activation of PKN by caspase-3 or related protease during apoptosis. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[15] Y. Ono,et al. A Protein Kinase, PKN, Accumulates in Alzheimer Neurofibrillary Tangles and Associated Endoplasmic Reticulum-Derived Vesicles and Phosphorylates Tau Protein , 1998, The Journal of Neuroscience.
[16] Y. Ono,et al. Localization of PKN mRNA in the rat brain. , 1998, Brain research. Molecular brain research.
[17] K. Yamada,et al. Effector domain mutants of Rho dissociate cytoskeletal changes from nuclear signaling and cellular transformation , 1998, Oncogene.
[18] R. Treisman,et al. RhoA effector mutants reveal distinct effector pathways for cytoskeletal reorganization, SRF activation and transformation , 1998, The EMBO journal.
[19] Tsonwin Hai,et al. Epidermal Growth Factor Induction of the c-jun Promoter by a Rac Pathway , 1998, Molecular and Cellular Biology.
[20] A. Hall,et al. Rho GTPases and the actin cytoskeleton. , 1998, Science.
[21] Roger J. Davis,et al. Selective Activation of p38 Mitogen-activated Protein (MAP) Kinase Isoforms by the MAP Kinase Kinases MKK3 and MKK6* , 1998, The Journal of Biological Chemistry.
[22] Jiahuai Han,et al. BMK1/ERK5 regulates serum‐induced early gene expression through transcription factor MEF2C , 1997, The EMBO journal.
[23] Shuh Narumiya,et al. Calcium sensitization of smooth muscle mediated by a Rho-associated protein kinase in hypertension , 1997, Nature.
[24] L. Van Aelst,et al. Rho GTPases and signaling networks. , 1997, Genes & development.
[25] J. Gutkind,et al. Signaling from G Protein-coupled Receptors to the c-jun Promoter Involves the MEF2 Transcription Factor , 1997, The Journal of Biological Chemistry.
[26] J C Lee,et al. Novel homologues of CSBP/p38 MAP kinase: activation, substrate specificity and sensitivity to inhibition by pyridinyl imidazoles. , 1997, Biochemical and biophysical research communications.
[27] Y. Watanabe,et al. Characterization of a serum response factor-like protein in Saccharomyces cerevisiae, Rlm1, which has transcriptional activity regulated by the Mpk1 (Slt2) mitogen-activated protein kinase pathway , 1997, Molecular and cellular biology.
[28] K. Robbins,et al. Tyrosine Phosphorylation of the vav Proto-oncogene Product Links FcεRI to the Rac1-JNK Pathway* , 1997, The Journal of Biological Chemistry.
[29] E. Dodou,et al. The Saccharomyces cerevisiae MADS-box transcription factor Rlm1 is a target for the Mpk1 mitogen-activated protein kinase pathway , 1997, Molecular and cellular biology.
[30] J. Settleman,et al. The PRK2 kinase is a potential effector target of both Rho and Rac GTPases and regulates actin cytoskeletal organization , 1997, Molecular and cellular biology.
[31] K. Kaibuchi,et al. Formation of Actin Stress Fibers and Focal Adhesions Enhanced by Rho-Kinase , 1997, Science.
[32] Shengcai Lin,et al. Identification and characterization of a predominant isoform of human MKK3 , 1997, FEBS letters.
[33] Philip R. Cohen,et al. Activation of stress‐activated protein kinase‐3 (SAPK3) by cytokines and cellular stresses is mediated via SAPKK3 (MKK6); comparison of the specificities of SAPK3 and SAPK2 (RK/p38) , 1997, The EMBO journal.
[34] O. Ornatsky,et al. MEF2 Protein Expression, DNA Binding Specificity and Complex Composition, and Transcriptional Activity in Muscle and Non-muscle Cells* , 1996, The Journal of Biological Chemistry.
[35] A. Ridley,et al. Rho: theme and variations , 1996, Current Biology.
[36] X. Q. Chen,et al. The p160 RhoA-binding kinase ROK alpha is a member of a kinase family and is involved in the reorganization of the cytoskeleton , 1996, Molecular and cellular biology.
[37] K. Nakao,et al. ROCK‐I and ROCK‐II, two isoforms of Rho‐associated coiled‐coil forming protein serine/threonine kinase in mice , 1996, FEBS letters.
[38] K. Fujisawa,et al. Rhotekin, a New Putative Target for Rho Bearing Homology to a Serine/Threonine Kinase, PKN, and Rhophilin in the Rho-binding Domain* , 1996, The Journal of Biological Chemistry.
[39] T. Yamamoto,et al. Rho‐associated kinase, a novel serine/threonine kinase, as a putative target for small GTP binding protein Rho. , 1996, The EMBO journal.
[40] M. Symons,et al. Rho family GTPases: the cytoskeleton and beyond. , 1996, Trends in biochemical sciences.
[41] A. Ullrich,et al. ERK6, a mitogen-activated protein kinase involved in C2C12 myoblast differentiation. , 1996, Proceedings of the National Academy of Sciences of the United States of America.
[42] M. Goedert,et al. SAP kinase‐3, a new member of the family of mammalian stress‐activated protein kinases , 1996, FEBS letters.
[43] R. Treisman,et al. Regulation of transcription by MAP kinase cascades. , 1996, Current opinion in cell biology.
[44] K. Fujisawa,et al. The small GTP‐binding protein Rho binds to and activates a 160 kDa Ser/Thr protein kinase homologous to myotonic dystrophy kinase. , 1996, The EMBO journal.
[45] 野中 秀太郎. A downstream target of RHO1 small GTP-binding protein is PKC1, a homolog of protein kinase C, which leads to activation of the MAP kinase cascade in Saccharomyces cerevisiae , 1996 .
[46] R. Davis,et al. MKK3- and MKK6-regulated gene expression is mediated by the p38 mitogen-activated protein kinase signal transduction pathway , 1996, Molecular and cellular biology.
[47] Jiahuai Han,et al. Characterization of the Structure and Function of a Novel MAP Kinase Kinase (MKK6) (*) , 1996, The Journal of Biological Chemistry.
[48] K. Fujisawa,et al. Protein Kinase N (PKN) and PKN-Related Protein Rhophilin as Targets of Small GTPase Rho , 1996, Science.
[49] K. Kaibuchi,et al. Identification of a Putative Target for Rho as the Serine-Threonine Kinase Protein Kinase N , 1996, Science.
[50] L. Lim,et al. A Novel Serine/Threonine Kinase Binding the Ras-related RhoA GTPase Which Translocates the Kinase to Peripheral Membranes (*) , 1995, The Journal of Biological Chemistry.
[51] F. McCormick,et al. A role for Rho in Ras transformation. , 1995, Proceedings of the National Academy of Sciences of the United States of America.
[52] K. Tanaka,et al. A downstream target of RHO1 small GTP‐binding protein is PKC1, a homolog of protein kinase C, which leads to activation of the MAP kinase cascade in Saccharomyces cerevisiae. , 1995, The EMBO journal.
[53] A. Ashworth,et al. An essential role for Rho, Rac, and Cdc42 GTPases in cell cycle progression through G1 , 1995, Science.
[54] T. Hunter,et al. Transcriptional control by protein phosphorylation: signal transmission from the cell surface to the nucleus , 1995, Current Biology.
[55] P. Crespo,et al. The small GTP-binding proteins Rac1 and Cdc42regulate the activity of the JNK/SAPK signaling pathway , 1995, Cell.
[56] M. Karin,et al. Selective activation of the JNK signaling cascadeand c-Jun transcriptional activity by the small GTPases Rac and Cdc42Hs , 1995, Cell.
[57] R. Treisman,et al. The Rho family GTPases RhoA, Racl , and CDC42Hsregulate transcriptional activation by SRF , 1995, Cell.
[58] R. Prywes,et al. Regulatory role of MEF2D in serum induction of the c-jun promoter , 1995, Molecular and cellular biology.
[59] A. Sharrocks,et al. The MADS-box family of transcription factors. , 1995, European journal of biochemistry.
[60] G. Pfeifer,et al. In vivo protein‐DNA interactions at the c‐jun promoter in quiescent and serum‐stimulated fibroblasts , 1995, Journal of cellular biochemistry.
[61] B. Dérijard,et al. Transcription factor ATF2 regulation by the JNK signal transduction pathway , 1995, Science.
[62] G L Johnson,et al. Differential activation of ERK and JNK mitogen-activated protein kinases by Raf-1 and MEKK. , 1994, Science.
[63] R. Davis,et al. MAPKs: new JNK expands the group. , 1994, Trends in biochemical sciences.
[64] Y. Ono,et al. Activation of PKN, a novel 120-kDa protein kinase with leucine zipper-like sequences, by unsaturated fatty acids and by limited proteolysis. , 1994, Biochemical and biophysical research communications.
[65] M. Karin,et al. c-Jun N-terminal phosphorylation correlates with activation of the JNK subgroup but not the ERK subgroup of mitogen-activated protein kinases , 1994, Molecular and cellular biology.
[66] P. Crespo,et al. Ras-dependent activation of MAP kinase pathway mediated by G-protein βγ subunits , 1994, Nature.
[67] H. Iba,et al. Analysis of AP-1 function in cellular transformation pathways , 1994, Journal of virology.
[68] I. Herr,et al. Binding of promoter-associated AP-1 is not altered during induction and subsequent repression of the c-jun promoter by TPA and UV irradiation. , 1994, Carcinogenesis.
[69] J. Woodgett,et al. The stress-activated protein kinase subfamily of c-Jun kinases , 1994, Nature.
[70] M. Karin,et al. JNK1: A protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain , 1994, Cell.
[71] R. Treisman. Ternary complex factors: growth factor regulated transcriptional activators. , 1994, Current opinion in genetics & development.
[72] M. Karin,et al. Identification of an oncoprotein- and UV-responsive protein kinase that binds and potentiates the c-Jun activation domain. , 1993, Genes & development.
[73] G. Pfeifer,et al. In vivo protein-DNA interactions at the c-jun promoter: preformed complexes mediate the UV response , 1993, Molecular and cellular biology.
[74] P. Warne,et al. Direct interaction of Ras and the amino-terminal region of Raf-1 in vitro , 1993, Nature.
[75] Jonathan A. Cooper,et al. Mammalian Ras interacts directly with the serine/threonine kinase raf , 1993, Cell.
[76] R. Davis,et al. The mitogen-activated protein kinase signal transduction pathway. , 1993, The Journal of biological chemistry.
[77] A. Papavassiliou,et al. Different TRE-related elements are distinguished by sets of DNA-binding proteins with overlapping sequence specificity. , 1993, Nucleic acids research.
[78] C. Crews,et al. The primary structure of MEK, a protein kinase that phosphorylates the ERK gene product. , 1992, Science.
[79] R. Treisman. The serum response element. , 1992, Trends in biochemical sciences.
[80] R. Prywes,et al. Mapping of epidermal growth factor-, serum-, and phorbol ester-responsive sequence elements in the c-jun promoter , 1992, Molecular and cellular biology.
[81] Anne J. Ridley,et al. The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors , 1992, Cell.
[82] A. Sharrocks,et al. Phosphorylation of transcription factor p62TCF by MAP kinase stimulates ternary complex formation at c-fos promoter , 1992, Nature.
[83] P. Herrlich,et al. ULTRAVIOLET‐RADIATION INDUCED c‐jun GENE TRANSCRIPTION: TWO AP‐1 LIKE BINDING SITES MEDIATE THE RESPONSE , 1992, Photochemistry and photobiology.
[84] R. Treisman,et al. Characterization of SAP-1, a protein recruited by serum response factor to the c-fos serum response element , 1992, Cell.
[85] M. Karin,et al. The role of Jun, Fos and the AP-1 complex in cell-proliferation and transformation. , 1991, Biochimica et biophysica acta.
[86] R. Bravo,et al. The jun and fos protein families are both required for cell cycle progression in fibroblasts , 1991, Molecular and cellular biology.
[87] B. Wasylyk,et al. Transformation suppressor activity of a Jun transcription factor lacking its activation domain , 1991, Nature.
[88] A. Hall,et al. Microinjection of recombinant p21rho induces rapid changes in cell morphology , 1990, The Journal of cell biology.
[89] R. Bravo. Growth factor-responsive genes in fibroblasts. , 1990, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.
[90] A. Nordheim,et al. The ability of a ternary complex to form over the serum response element correlates with serum inducibility of the human c-fos promoter , 1989, Cell.
[91] Peter Angel,et al. The jun proto-oncogene is positively autoregulated by its product, Jun/AP-1 , 1988, Cell.
[92] I. Verma,et al. Induction of proto-oncogene JUN/AP-1 by serum and TPA , 1988, Nature.
[93] R. Breathnach,et al. Epidermal growth factor stimulates transcription of the c-jun proto-oncogene in rat fibroblasts , 1988, Nature.
[94] B. Seed,et al. A simple phase-extraction assay for chloramphenicol acyltransferase activity. , 1988, Gene.
[95] T. Curran,et al. fra-1: a serum-inducible, cellular immediate-early gene that encodes a fos-related antigen , 1988, Molecular and cellular biology.
[96] L. Lau,et al. A gene activated by growth factors is related to the oncogene v-jun. , 1988, Proceedings of the National Academy of Sciences of the United States of America.
[97] M. Karin,et al. Phorbol ester-inducible genes contain a common cis element recognized by a TPA-modulated trans-acting factor , 1987, Cell.
[98] T. Sturgill,et al. Rapid stimulation by insulin of a serine/threonine kinase in 3T3-L1 adipocytes that phosphorylates microtubule-associated protein 2 in vitro. , 1987, Proceedings of the National Academy of Sciences of the United States of America.
[99] L. Lau,et al. Expression of a set of growth-related immediate early genes in BALB/c 3T3 cells: coordinate regulation with c-fos or c-myc. , 1987, Proceedings of the National Academy of Sciences of the United States of America.
[100] K. Nishikura,et al. Antisense RNA of proto-oncogene c-fos blocks renewed growth of quiescent 3T3 cells. , 1987, Molecular and cellular biology.
[101] K. Nishikura,et al. Antisense RNA of proto-oncogene c-fos blocks renewed growth of quiescent 3T3 cells , 1987 .
[102] Jiahuai Han,et al. The p38 signal transduction pathway: activation and function. , 2000, Cellular signalling.
[103] Jiahuai Han,et al. Regulation of the MEF 2 Family of Transcription Factors by p 38 † , 1998 .
[104] P. Parker,et al. Cloning and expression patterns of two members of a novel protein-kinase-C-related kinase family. , 1995, European journal of biochemistry.
[105] P. Crespo,et al. Ras-dependent activation of MAP kinase pathway mediated by G-protein beta gamma subunits. , 1994, Nature.
[106] K. Jalink,et al. Mitogenic action of lysophosphatidic acid and phosphatidic acid on fibroblasts. Dependence on acyl-chain length and inhibition by suramin. , 1992, The Biochemical journal.
[107] H. Herschman. Primary response genes induced by growth factors and tumor promoters. , 1991, Annual review of biochemistry.
[108] T. Sturgill,et al. Rapid stimulation by insulin of a serine / threonine kinase in 3 T 3L 1 adipocytes that phosphorylates microtubule-associated protein 2 in vitro ( ribosomal protein S 6 kinase / phosphatase inhibitors ) , 2022 .