Multifocal intraosseous hemangioma

Rationale: Multifocal intraosseous hemangioma, which affects multiple body parts, is rare. The selection of appropriate lesion sites for biopsy and effective treatment in multifocal intraosseous hemangioma is challenging. Here, we report a case of multifocal intraosseous hemangioma. Patient concerns: A 49-year-old woman was admitted to our department with a chief complaint of aggravated lumber pain for 10 days. Diagnoses: Radiographic imaging revealed lesions involving the bilateral ribs, lumbar vertebrae, ilium, pubis, and proximal femur. Open biopsy in the ilium established the pathological diagnosis of intraosseous hemangioma. Interventions: For the symptomatic lumbar spine, the patient selected radiotherapy as the initial treatment. Outcomes: As of the one-year follow-up, no symptoms of recurrence have been observed. Lessons: This rare case demonstrates the importance of the selection of the appropriate lesion to confirm the diagnosis and effective treatment for patients with multifocal disease. Radiotherapy plays an important role in the treatment of patients with symptomatic vertebral hemangiomas without neurologic deficits.