Ultrasound in hepatoma-can specific diagnosis be made?

The ultrasound appearances of primary hepatocellular carcinoma in 32 patients are described. Attempts to correlate the appearances with serological, histological, and arteriographic findings revealed no consistent pattern. There appears to be no great difference in the range of ultrasound appearances in primary hepatocellular carcinoma when compared with that reported for metastatic disease. The findings suggest that in patients with cirrhosis, ultrasound is a sensitive method for the detection and accurate location of hepatocellular carcinoma, but that in these patients the echo pattern provides little help in the differentiation of primary from secondary carcinoma. Our study has revealed four different echo patterns in patients with hepatocellular carcinoma: echofree (47%), echogenic (23%), mixed (175) and diffuse infiltration 13%).

[1]  B. Gosink,et al.  Echographic and radionuclide detection of hepatoma. , 1980, Radiology.

[2]  M. Bernardino,et al.  Ultrasound manifestations of hepatocellular carcinoma. , 1979, Radiology.

[3]  Á. Ruibal,et al.  CARCINOEMBRYONIC ANTIGEN IN LIVER DISEASE , 1979, The Lancet.

[4]  V. R. McCready,et al.  Diagnosis of Liver Metastases Using Ultrasound and Isotope Scanning Techniques , 1978, Journal of the Royal Society of Medicine.

[5]  Roger Williams,et al.  INDUCTION OF REMISSION IN HEPATOCELLULAR CARCINOMA WITH DOXORUBICIN , 1978, The Lancet.

[6]  S. Sakaguchi,et al.  Value of B-scan ultrasonography in the diagnosis of liver cancer. Accuracy compared to scintigraphy and angiography. , 1978, The American journal of gastroenterology.

[7]  K. Okuda,et al.  Detection of hepatocellular carcinoma during a clinical follow-up of chronic liver disease: observations in 31 patients. , 1978, Gastroenterology.

[8]  B B Gosink,et al.  Gray scale echographic patterns of hepatic metastatic disease. , 1977, AJR. American journal of roentgenology.

[9]  J. Pedersen,et al.  Ultrasonic scanning for focal liver lesions. , 1977, Danish medical bulletin.

[10]  D. Brinkley,et al.  Quadruple chemotherapy versus radiotherapy in treatment of primary hepatocellular carcinoma , 1977, Cancer.

[11]  H. Goldstein,et al.  Gray scale ultrasound evaluation of hepatic neoplasms: patterns and correlations. , 1977, Radiology.

[12]  A. Afroudakis,et al.  The changing incidence of association of hepatitis B with hepatocellular carcinoma in California. , 1977, American journal of clinical pathology.

[13]  H. Conn Nuclide scanning, ultrasonography and liver biopsy in the diagnosis of hepatic tumours: a comparative evaluation of the available techniques. , 1976, Clinics in gastroenterology.

[14]  R. Simon,et al.  A staging system for hepatocellular carcinoma: Prognostic factors in Ugandan patients , 1975, Cancer.

[15]  P. Anthony Primary carcinoma of the liver: A study of 282 cases in Ugandan Africans , 1973, The Journal of pathology.

[16]  K. Taylor Manual of ultrasonography , 1980 .

[17]  J. Boultbee Grey scale ultrasound appearances in hepatocellular carcinoma. , 1979, Clinical radiology.