TBHP-Mediated Oxidative Thiolation of an sp3 C—H Bond Adjacent to a Nitrogen Atom in an Amide.

The oxidative thiolation of N,N-dimethylacetamide (IIa) leads to a variety of sulfides (V) as sole reaction products, while the analogous reaction of N,N-dimethylformamide (VI) and 1-methylpyrrolidin-one (IX) gives rise to a mixture of 2 derivatives.