An investigation of several deoxynucleoside phosphoramidites useful for synthesizing deoxyoligonucleotides
暂无分享,去创建一个
Abstract Various deoxynucleoside N,N-dialkylaminomethoxyphosphines were examined for stability and reactivity in deoxyoligonucleotide synthesis. Of those examined, the N-morpholino and N,N-diisopropylamino derivatives most completely satisfied all criteria.
[1] D. Shire,et al. New intermediates for the synthesis of oligonucleotides by the phosphite triester approach , 1981 .
[2] M. Caruthers,et al. Deoxynucleoside phosphoramidites—A new class of key intermediates for deoxypolynucleotide synthesis , 1981 .
[3] R. Pike,et al. Preparation of β-Cyanoethyltrichlorosilane Using Silylamine Catalysts , 1962 .