The epigenetic processes of meiosis in male mice are broadly affected by the widely used herbicide atrazine

[1]  Yuanxiang Jin,et al.  Oral exposure of pubertal male mice to endocrine‐disrupting chemicals alters fat metabolism in adult livers , 2015, Environmental toxicology.

[2]  R. Fletterick,et al.  Silencing LRH-1 in colon cancer cell lines impairs proliferation and alters gene expression programs , 2015, Proceedings of the National Academy of Sciences.

[3]  F. Bard,et al.  The small GTPase Arf1 modulates mitochondrial morphology and function , 2014, The EMBO journal.

[4]  Shweta Sharma,et al.  Melatonin Reverses Fas, E2F-1 and Endoplasmic Reticulum Stress Mediated Apoptosis and Dysregulation of Autophagy Induced by the Herbicide Atrazine in Murine Splenocytes , 2014, PloS one.

[5]  C. Richter,et al.  Atrazine reduces reproduction in Japanese medaka (Oryzias latipes). , 2014, Aquatic toxicology.

[6]  N. Soliman,et al.  Modulatory Effects of Curcumin on Redox Status, Mitochondrial Function, and Caspace‐3 Expression During Atrazin‐Induced Toxicity , 2014, Journal of biochemical and molecular toxicology.

[7]  H. Vereecken,et al.  Atrazine soil core residue analysis from an agricultural field 21 years after its ban. , 2014, Journal of environmental quality.

[8]  C. Boutin,et al.  Atrazine contamination at the watershed scale and environmental factors affecting sampling rates of the polar organic chemical integrative sampler (POCIS). , 2014, Environmental pollution.

[9]  D. Shaw,et al.  Water quality survey of Mississippi's Upper Pearl River. , 2014, The Science of the total environment.

[10]  C. L. Baker,et al.  PRDM9 binding organizes hotspot nucleosomes and limits Holliday junction migration , 2014, Genome research.

[11]  Yuanxiang Jin,et al.  Exposure of mice to atrazine and its metabolite diaminochlorotriazine elicits oxidative stress and endocrine disruption. , 2014, Environmental toxicology and pharmacology.

[12]  H. Vereecken,et al.  20 years of long-term atrazine monitoring in a shallow aquifer in western Germany. , 2014, Water research.

[13]  A. Bittner,et al.  Comparison of RNA-Seq and Microarray in Transcriptome Profiling of Activated T Cells , 2014, PloS one.

[14]  J. Blahova,et al.  Oxidative stress responses in zebrafish Danio rerio after subchronic exposure to atrazine. , 2013, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

[15]  R. Camerini-Otero,et al.  Suppression of genetic recombination in the pseudoautosomal region and at subtelomeres in mice with a hypomorphic Spo11 allele , 2013, BMC Genomics.

[16]  A. Bradley,et al.  ATR acts stage specifically to regulate multiple aspects of mammalian meiotic silencing , 2013, Genes & development.

[17]  N. Andric,et al.  Involvement of ERK1/2 signaling pathway in atrazine action on FSH-stimulated LHR and CYP19A1 expression in rat granulosa cells. , 2013, Toxicology and applied pharmacology.

[18]  Y. Lu,et al.  Exposure to bisphenol A disrupts meiotic progression during spermatogenesis in adult rats through estrogen-like activity , 2013, Cell Death and Disease.

[19]  D. Voutsa,et al.  Twenty years later--atrazine concentrations in selected coastal waters of the Mediterranean and the Baltic Sea. , 2013, Marine pollution bulletin.

[20]  Rebecca Tracey,et al.  Pesticide and insect repellent mixture (permethrin and DEET) induces epigenetic transgenerational inheritance of disease and sperm epimutations. , 2012, Reproductive toxicology.

[21]  F. Bianchi,et al.  Atrazine disrupts steroidogenesis, VEGF and NO production in swine granulosa cells. , 2012, Ecotoxicology and environmental safety.

[22]  Jun S. Song,et al.  CHANCE: comprehensive software for quality control and validation of ChIP-seq data , 2012, Genome Biology.

[23]  P. Chambon,et al.  Retinoic acid induces Sertoli cell paracrine signals for spermatogonia differentiation but cell autonomously drives spermatocyte meiosis , 2012, Proceedings of the National Academy of Sciences.

[24]  K. Nishimori,et al.  Impairment of Pachytene Spermatogenesis in Dmrt7 Deficient Mice, Possibly Causing Meiotic Arrest , 2012, Bioscience, biotechnology, and biochemistry.

[25]  R. Sharma,et al.  Antioxidant Attenuation of Atrazine Induced Histopathological Changes in Testicular Tissue of Goat In Vitro , 2012, Toxicology international.

[26]  Yong Zhang,et al.  Identifying ChIP-seq enrichment using MACS , 2012, Nature Protocols.

[27]  A. Pant,et al.  Kolaviron Biflavanoids of Garcinia Kola Seeds Protect Atrazine-Induced Cytotoxicity in Primary Cultures of Rat Leydig Cells , 2012, International journal of toxicology.

[28]  Helga Thorvaldsdóttir,et al.  Integrative Genomics Viewer (IGV): high-performance genomics data visualization and exploration , 2012, Briefings Bioinform..

[29]  M. A. Marin-Morales,et al.  Early cytotoxic and genotoxic effects of atrazine on Wistar rat liver: a morphological, immunohistochemical, biochemical, and molecular study. , 2012, Ecotoxicology and environmental safety.

[30]  Kevin Brick,et al.  Genetic recombination is directed away from functional genomic elements in mice , 2012, Nature.

[31]  M. T. Parra,et al.  Inactivation or non-reactivation: what accounts better for the silence of sex chromosomes during mammalian male meiosis? , 2012, Chromosoma.

[32]  K. Hofmann,et al.  Inhibition of homologous recombination by the PCNA-interacting protein PARI. , 2012, Molecular cell.

[33]  Peter J. Bickel,et al.  Measuring reproducibility of high-throughput experiments , 2011, 1110.4705.

[34]  William Stafford Noble,et al.  Improved similarity scores for comparing motifs , 2011, Bioinform..

[35]  Kevin Brick,et al.  Genome-wide analysis reveals novel molecular features of mouse recombination hotspots , 2011, Nature.

[36]  Philip Machanick,et al.  MEME-ChIP: motif analysis of large DNA datasets , 2011, Bioinform..

[37]  J. Bhatti,et al.  Ameliorative action of melatonin on oxidative damage induced by atrazine toxicity in rat erythrocytes , 2011, Molecular and Cellular Biochemistry.

[38]  Gaël Durand,et al.  Urinary Biomarkers of Prenatal Atrazine Exposure and Adverse Birth Outcomes in the PELAGIE Birth Cohort , 2011, Environmental health perspectives.

[39]  M. Giordano,et al.  Chronic atrazine exposure causes disruption of the spontaneous locomotor activity and alters the striatal dopaminergic system of the male Sprague-Dawley rat. , 2011, Neurotoxicology and teratology.

[40]  S. Keeney,et al.  Distinct Properties of the XY Pseudoautosomal Region Crucial for Male Meiosis , 2011, Science.

[41]  P. Allard,et al.  Bisphenol A impairs the double-strand break repair machinery in the germline and causes chromosome abnormalities , 2010, Proceedings of the National Academy of Sciences.

[42]  V. Dakić,et al.  Upregulation of peripubertal rat Leydig cell steroidogenesis following 24 h in vitro and in vivo exposure to atrazine. , 2010, Toxicological sciences : an official journal of the Society of Toxicology.

[43]  A. Hyman,et al.  Quantitative Interaction Proteomics and Genome-wide Profiling of Epigenetic Histone Marks and Their Readers , 2010, Cell.

[44]  B. Siegfried,et al.  Proteomic analysis of atrazine exposure in Drosophila melanogaster (Diptera: Drosophilidae). , 2010, Chemosphere.

[45]  C. A. Oliveira,et al.  Changes in testicular morphology and steroidogenesis in adult rats exposed to Atrazine. , 2010, Reproductive toxicology.

[46]  M. Oyeyemi,et al.  Changes in Sperm Characteristics and Induction of Oxidative Stress in the Testis and Epididymis of Experimental Rats by a Herbicide, Atrazine , 2010, Archives of environmental contamination and toxicology.

[47]  David G Mets,et al.  RTEL-1 Enforces Meiotic Crossover Interference and Homeostasis , 2010, Science.

[48]  R. Sandhir,et al.  Oxidative stress induced by atrazine in rat erythrocytes: Mitigating effect of vitamin E , 2010, Toxicology mechanisms and methods.

[49]  A. Paoloni-Giacobino,et al.  Transgenerational effects of the endocrine disruptor vinclozolin on the methylation pattern of imprinted genes in the mouse sperm. , 2010, Reproduction.

[50]  N. Terada,et al.  Adenine nucleotide translocase 4 deficiency leads to early meiotic arrest of murine male germ cells. , 2009, Reproduction.

[51]  Vanja Dakic,et al.  Atrazine oral exposure of peripubertal male rats downregulates steroidogenesis gene expression in Leydig cells. , 2009, Toxicological sciences : an official journal of the Society of Toxicology.

[52]  J. Frankenberger,et al.  Drinking-Water Herbicide Exposure in Indiana and Prevalence of Small-for-Gestational-Age and Preterm Delivery , 2009, Environmental health perspectives.

[53]  Loretta Auvil,et al.  Breakpoint regions and homologous synteny blocks in chromosomes have different evolutionary histories. , 2009, Genome research.

[54]  S. Ahn,et al.  Chronic Exposure to the Herbicide, Atrazine, Causes Mitochondrial Dysfunction and Insulin Resistance , 2009, PloS one.

[55]  Cestmir Vlcek,et al.  A Mouse Speciation Gene Encodes a Meiotic Histone H3 Methyltransferase , 2009, Science.

[56]  S. Baylin,et al.  Double Strand Breaks Can Initiate Gene Silencing and SIRT1-Dependent Onset of DNA Methylation in an Exogenous Promoter CpG Island , 2008, PLoS genetics.

[57]  E. C. Silva-Zacarin,et al.  Effects of atrazine on female Wistar rats: morphological alterations in ovarian follicles and immunocytochemical labeling of 90 kDa heat shock protein. , 2008, Micron.

[58]  H. Ingraham,et al.  The Herbicide Atrazine Activates Endocrine Gene Networks via Non-Steroidal NR5A Nuclear Receptors in Fish and Mammalian Cells , 2008, PloS one.

[59]  Frédéric Chalmel,et al.  The Annotation, Mapping, Expression and Network (AMEN) suite of tools for molecular systems biology , 2008, BMC Bioinformatics.

[60]  Ping Zhang,et al.  RETRACTED: Testicular Toxicity and Mechanisms of Chlorotoluron Compounds in the Mouse , 2008, Toxicology Mechanisms and Methods.

[61]  C. Freudenreich,et al.  An AT-rich sequence in human common fragile site FRA16D causes fork stalling and chromosome breakage in S. cerevisiae. , 2007, Molecular cell.

[62]  T. Yanase,et al.  Herbicide atrazine activates SF-1 by direct affinity and concomitant co-activators recruitments to induce aromatase expression via promoter II. , 2007, Biochemical and biophysical research communications.

[63]  T. Kouzarides.  Chromatin Modifications and Their Function , 2007, Cell.

[64]  Z. Ping,et al.  Testicular Toxicity and Mechanisms of Chlorotoluron Compounds in the Mouse , 2007, Toxicology Mechanisms and Methods.

[65]  L. Anderson,et al.  Lack of effects of atrazine on estrogen-responsive organs and circulating hormone concentrations in sexually immature female Japanese quail (Coturnix coturnix japonica). , 2006, Chemosphere.

[66]  Jun Song,et al.  CEAS: cis-regulatory element annotation system , 2006, Nucleic Acids Res..

[67]  P. Hunt,et al.  Meiosis and sex chromosome aneuploidy: how meiotic errors cause aneuploidy; how aneuploidy causes meiotic errors. , 2006, Current opinion in genetics & development.

[68]  David I. Smith,et al.  Common fragile sites, extremely large genes, neural development and cancer. , 2006, Cancer letters.

[69]  Y. Matsui,et al.  A histone H3 methyltransferase controls epigenetic events required for meiotic prophase , 2005, Nature.

[70]  Paul D. Jones,et al.  Effects of atrazine on CYP19 gene expression and aromatase activity in testes and on plasma sex steroid concentrations of male African clawed frogs (Xenopus laevis). , 2005, Toxicological sciences : an official journal of the Society of Toxicology.

[71]  C. Deng,et al.  BRCA1, Histone H2AX Phosphorylation, and Male Meiotic Sex Chromosome Inactivation , 2004, Current Biology.

[72]  B. Jégou,et al.  The Testicular Form of Hormone-sensitive Lipase HSLtes Confers Rescue of Male Infertility in HSL-deficient Mice* , 2004, Journal of Biological Chemistry.

[73]  M. Andersen,et al.  Evidence that atrazine and diaminochlorotriazine inhibit the estrogen/progesterone induced surge of luteinizing hormone in female Sprague-Dawley rats without changing estrogen receptor action. , 2004, Toxicological sciences : an official journal of the Society of Toxicology.

[74]  S. Andò,et al.  Differential expression of steroidogenic factor-1/adrenal 4 binding protein and liver receptor homolog-1 (LRH-1)/fetoprotein transcription factor in the rat testis: LRH-1 as a potential regulator of testicular aromatase expression. , 2004, Endocrinology.

[75]  Scott Keeney,et al.  Tying synaptonemal complex initiation to the formation and programmed repair of DNA double-strand breaks. , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[76]  Terry Speed,et al.  Normalization of cDNA microarray data. , 2003, Methods.

[77]  F. Fabre,et al.  The Srs2 helicase prevents recombination by disrupting Rad51 nucleoprotein filaments , 2003, Nature.

[78]  C. Hodges,et al.  Bisphenol A Exposure Causes Meiotic Aneuploidy in the Female Mouse , 2003, Current Biology.

[79]  Louis Renault,et al.  Arf, Arl, Arp and Sar proteins: a family of GTP‐binding proteins with a structural device for ‘front–back’ communication , 2002, EMBO reports.

[80]  T. Hayes,et al.  Herbicides: Feminization of male frogs in the wild , 2002, Nature.

[81]  Kelly Haston,et al.  Atrazine-induced hermaphroditism at 0.1 ppb in American leopard frogs (Rana pipiens): laboratory and field evidence. , 2002, Environmental health perspectives.

[82]  J. Miyake,et al.  Induction of P-glycoprotein, glutathione-S-transferase and cytochrome P450 in rat liver by atrazine. , 2002, Environmental toxicology and pharmacology.

[83]  S. Jackson,et al.  Sensing and repairing DNA double-strand breaks. , 2002, Carcinogenesis.

[84]  D. Wake,et al.  Hermaphroditic, demasculinized frogs after exposure to the herbicide atrazine at low ecologically relevant doses , 2002, Proceedings of the National Academy of Sciences of the United States of America.

[85]  Freya Q. Schafer,et al.  Redox environment of the cell as viewed through the redox state of the glutathione disulfide/glutathione couple. , 2001, Free radical biology & medicine.

[86]  S. Keeney,et al.  Recombinational DNA double-strand breaks in mice precede synapsis , 2001, Nature Genetics.

[87]  Robert T Youker,et al.  Atrazine effects on testosterone levels and androgen-dependent reproductive organs in peripubertal male rats. , 2001, Journal of andrology.

[88]  M. van den Berg,et al.  2-Chloro-s-triazine herbicides induce aromatase (CYP19) activity in H295R human adrenocortical carcinoma cells: a novel mechanism for estrogenicity? , 2000, Toxicological sciences : an official journal of the Society of Toxicology.

[89]  Andrew A. Rooney,et al.  Alterations in steroidogenesis in alligators (Alligator mississippiensis) exposed naturally and experimentally to environmental contaminants. , 1997, Environmental health perspectives.

[90]  Irene Garcia,et al.  An early and massive wave of germinal cell apoptosis is required for the development of functional spermatogenesis , 1997, The EMBO journal.

[91]  P. de Boer,et al.  SHORT COMMUNICATIONS A drying-down technique for the spreading of mammalian meiocytes from the male and female germline , 1997, Chromosome Research.

[92]  R. Cooper,et al.  Effect of atrazine on ovarian function in the rat. , 1996, Reproductive toxicology.

[93]  A. Musio,et al.  Enhanced expression of common fragile site with occupational exposure to pesticides. , 1995, Cancer genetics and cytogenetics.

[94]  S. Ćurić,et al.  Serum biochemical and histopathological changes related to the hepatic function in pigs following atrazine treatment , 1995, Journal of applied toxicology : JAT.

[95]  D. Reddy,et al.  Atrazine toxicity on hydromineral balance of fish, Tilapia mossambicus. , 1994, Ecotoxicology and environmental safety.

[96]  R. Hammer,et al.  Hypercholesterolemia in low density lipoprotein receptor knockout mice and its reversal by adenovirus-mediated gene delivery. , 1993, The Journal of clinical investigation.

[97]  J. Kniewald,et al.  Testosterone metabolism in neuroendocrine organs in male rats under atrazine and deethylatrazine influence. , 1989, Journal of steroid biochemistry.

[98]  Spain,et al.  Hepatotoxicity induced by the herbicide atrazine in the rat , 1987, Journal of applied toxicology : JAT.

[99]  C. Jefcoate,et al.  ACTH control of cholesterol side-chain cleavage at adrenal mitochondrial cytochrome P-450scc. Regulation of intramitochondrial cholesterol transfer , 1987, Molecular and Cellular Endocrinology.

[100]  C. Jefcoate,et al.  Regulation of intramitochondrial cholesterol transfer to side-chain cleavage cytochrome P-450 in rat adrenal gland. , 1983, Proceedings of the National Academy of Sciences of the United States of America.

[101]  C. L. Nash,et al.  Mutagenicity of the triazine herbicides atrazine, cyanazine, and simazine in Drosophila melanogaster. , 1977, Journal of toxicology and environmental health.

[102]  G. S. Boyd,et al.  The effect of ether anaesthesia stress on cholesterol-side-chain cleavage and cytochrome P450 in rat-adrenal mitochondria. , 1972, European journal of biochemistry.

[103]  M. Laušević,et al.  Determination of pharmaceuticals and pesticides in river sediments and corresponding surface and ground water in the Danube River and tributaries in Serbia , 2014, Environmental Monitoring and Assessment.

[104]  Brad T. Sherman,et al.  Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources , 2008, Nature Protocols.

[105]  A. Shiratsuchi,et al.  Phagocytic removal of apoptotic spermatogenic cells by Sertoli cells: mechanisms and consequences. , 2004, Biological & pharmaceutical bulletin.

[106]  A. Musio,et al.  Aphidicolin‐sensitive specific common fragile sites: A biomarker of exposure to pesticides , 1997, Environmental and molecular mutagenesis.

[107]  L. Russell,et al.  Histological and Histopathological Evaluation of the Testis , 1990 .