Cytochrome P450-dependent toxicity of environmental polycyclic aromatic hydrocarbons towards human macrophages.

[1]  C. Heidelberger,et al.  Metabolism of polycyclic aromatic hydrocarbons in cell cultuires. , 1971, Cancer research.

[2]  T. Shih,et al.  Inhibition of benzo(alpha)pyrene metabolism catalyzed by mouse and hamster lung microsomes. , 1975, Cancer research.

[3]  Suppressive effect of 3-methylcholanthrene on phagocytic activity of mouse peritoneal macrophages for Torulopsis glabrata. , 1979, Journal of the National Cancer Institute.

[4]  Zedeck Ms Polycyclic aromatic hydrocarbons: a review. , 1980 .

[5]  R. Irons,et al.  Immunosuppression following 7,12-dimethylbenz[a]anthracene exposure in B6C3F1 mice. I. Effects on humoral immunity and host resistance. , 1984, Toxicology and applied pharmacology.

[6]  L. Alfred,et al.  Alterations in cell-mediated immune functions induced in mouse splenic lymphocytes by polycyclic aromatic hydrocarbons. , 1984, Cancer research.

[7]  M. Lyte,et al.  Modulation of interleukin-1 production by macrophages following benzo(a)pyrene exposure. , 1986, International journal of immunopharmacology.

[8]  J. A. Blank,et al.  alpha-Naphthoflavone antagonism of 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced murine lymphocyte ethoxyresorufin-O-deethylase activity and immunosuppression. , 1987, Molecular pharmacology.

[9]  Persistent suppression of humoral immunity produced by 7,12-dimethylbenz(A)anthracene (DMBA) in B6C3F1 mice: correlation with changes in spleen cell surface markers detected by flow cytometry. , 1988, International journal of immunopharmacology.

[10]  S. Clark,et al.  Comparison of the effects of IL-3, granulocyte-macrophage colony-stimulating factor, and macrophage colony-stimulating factor in supporting monocyte differentiation in culture. Analysis of macrophage antibody-dependent cellular cytotoxicity. , 1990, Journal of immunology.

[11]  W. Lijinsky The formation and occurrence of polynuclear aromatic hydrocarbons associated with food. , 1991, Mutation research.

[12]  S. De Flora,et al.  Benzo[a]pyrene diolepoxide-DNA adducts in alveolar macrophages of smokers. , 1991, Carcinogenesis.

[13]  C. Travis,et al.  Benzo-a-Pyrene: Environmental Partitioning and Human Exposure , 1991, Toxicology and industrial health.

[14]  C. Ioannides,et al.  Induction of cytochrome P4501 as an indicator of potential chemical carcinogenesis. , 1993, Drug metabolism reviews.

[15]  Effects of 7,12-dimethylbenz[a]anthracene on the superantigen toxic shock syndrome toxin (TSST-1)-induced proliferation and antibody secretion by human lymphocytes. , 1993, Fundamental and applied toxicology : official journal of the Society of Toxicology.

[16]  N. Z. Alsharif,et al.  Oxidative stress induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin is mediated by the aryl hydrocarbon (Ah) receptor complex. , 1994, Toxicology.

[17]  K. Peltonen,et al.  Chemical and mutagenic specificities of polycyclic aromatic hydrocarbon carcinogens. , 1994, Advances in experimental medicine and biology.

[18]  M. Rämet,et al.  p53Protein expression is correlated with benzo[a]pyrene-DNA adducts in carcinoma cell lines , 1995 .

[19]  O. Hankinson The aryl hydrocarbon receptor complex. , 1995, Annual review of pharmacology and toxicology.

[20]  S. Burchiel,et al.  Human T cells are highly sensitive to suppression of mitogenesis by polycyclic aromatic hydrocarbons and this effect is differentially reversed by alpha-naphthoflavone. , 1996, Toxicology and applied pharmacology.

[21]  W. Lei,et al.  Induction of apoptosis and activation of interleukin 1beta-converting enzyme/Ced-3 protease (caspase-3) and c-Jun NH2-terminal kinase 1 by benzo(a)pyrene. , 1998, Cancer research.

[22]  S. Burchiel,et al.  Apoptosis in Daudi human B cells in response to benzo[a]pyrene and benzo[a]pyrene-7,8-dihydrodiol. , 1998, Toxicology and applied pharmacology.

[23]  C. Lutz,et al.  Methylcholanthrene causes increased thymocyte apoptosis. , 1998, Toxicology.

[24]  A. Valm,et al.  Immunotoxicology of cigarette smoke condensates: suppression of macrophage responsiveness to interferon gamma. , 1998, Toxicology and applied pharmacology.

[25]  S. Hecht,et al.  Tobacco smoke carcinogens and lung cancer. , 1999, Journal of the National Cancer Institute.

[26]  H. Perlman,et al.  Flice-Inhibitory Protein Expression during Macrophage Differentiation Confers Resistance to FAS-Mediated Apoptosis , 1999, The Journal of experimental medicine.

[27]  N. Kerkvliet,et al.  The role of polycyclic aromatic hydrocarbon metabolism in dimethylbenz[a]anthracene-induced pre-B lymphocyte apoptosis. , 1999, Toxicology and applied pharmacology.

[28]  M. Knize,et al.  Food heating and the formation of heterocyclic aromatic amine and polycyclic aromatic hydrocarbon mutagens/carcinogens. , 1999, Advances in experimental medicine and biology.

[29]  K. Ramos,et al.  Activation of c-Ha-ras by benzo(a)pyrene in vascular smooth muscle cells involves redox stress and aryl hydrocarbon receptor. , 2000, Molecular pharmacology.

[30]  M. Burke,et al.  Bioflavonoids: selective substrates and inhibitors for cytochrome P450 CYP1A and CYP1B1. , 2000, Toxicology.

[31]  M. Grütter,et al.  Caspases: key players in programmed cell death. , 2000, Current opinion in structural biology.

[32]  F. Carlotti,et al.  Bcl-xL Expression Correlates with Primary Macrophage Differentiation, Activation of Functional Competence, and Survival and Results from Synergistic Transcriptional Activation by Ets2 and PU.1* , 2001, The Journal of Biological Chemistry.

[33]  H. Perlman,et al.  Constitutively Activated Akt-1 Is Vital for the Survival of Human Monocyte-Differentiated Macrophages , 2001, The Journal of experimental medicine.

[34]  S. Burchiel,et al.  Signaling by environmental polycyclic aromatic hydrocarbons in human lymphocytes. , 2001, Clinical immunology.

[35]  O. Fardel,et al.  Polycyclic Aromatic Hydrocarbons Affect Functional Differentiation and Maturation of Human Monocyte-Derived Dendritic Cells1 , 2002, The Journal of Immunology.

[36]  M. Bernard,et al.  Potassium antimonyl tartrate induces caspase‐ and reactive oxygen species‐dependent apoptosis in lymphoid tumoral cells , 2002, British journal of haematology.

[37]  D. Lagadic-Gossmann,et al.  Liver Protection from Apoptosis Requires Both Blockage of Initiator Caspase Activities and Inhibition of ASK1/JNK Pathway via Glutathione S-Transferase Regulation* , 2002, The Journal of Biological Chemistry.

[38]  T. Page,et al.  7,12-Dimethylbenz[a]anthracene induces apoptosis in murine pre-B cells through a caspase-8-dependent pathway. , 2002, Molecular pharmacology.

[39]  J. van Grevenynghe,et al.  Polycyclic Aromatic Hydrocarbons Inhibit Differentiation of Human Monocytes into Macrophages1 , 2003, The Journal of Immunology.

[40]  R. Tukey,et al.  The Role of the Ah Receptor and p38 in Benzo[a]pyrene-7,8-dihydrodiol and Benzo[a]pyrene-7,8-dihydrodiol-9,10-epoxide-induced Apoptosis* , 2003, Journal of Biological Chemistry.

[41]  J. Karras,et al.  macrophage survival Serine phosphorylation of STAT 3 is essential for Mcl-1 expression and , 2003 .

[42]  T. Page,et al.  7,12-Dimethylbenz[a]anthracene-induced bone marrow toxicity is p53-dependent. , 2003, Toxicological sciences : an official journal of the Society of Toxicology.

[43]  D. Trichopoulos,et al.  Dioxin and cancer: a critical review. , 2003, Regulatory toxicology and pharmacology : RTP.

[44]  L. Poellinger,et al.  Aryl hydrocarbon receptor/dioxin receptor in human monocytes and macrophages , 2001, Molecular and Cellular Biochemistry.

[45]  K. Akagawa Functional Heterogeneity of Colony-Stimulating Factor-Induced Human Nonocyte-Derived Macrophages , 2002, Respirology.