4-Amino-3(2H)-pyridazinones bearing arylpiperazinylalkyl groups and related compounds: synthesis and antinociceptive activity.

[1]  T. Twomey,et al.  The analgetic properties of piroxicam in animals and correlation with expreimentally determined plasma levels , 1980, Agents and Actions.

[2]  R. Matucci,et al.  Antinociceptive activity of a 3(2H)-pyridazinone derivative in mice. , 1999, Life sciences.

[3]  V. D. Piaz,et al.  4,5-Functionalized 6-phenyl-3(2H)-pyridazinones: synthesis and evaluation of antinociceptive activity , 1996 .

[4]  P. Césaro,et al.  Pharmacology of neuropathic pain. , 1995, Clinical neuropharmacology.

[5]  P. Renard,et al.  N-substituted oxazolo[5,4-b]pyridin-2(1H)-ones: a new class of non-opiate antinociceptive agents. , 1995, Journal of medicinal chemistry.

[6]  E Albuisson,et al.  Synthesis of Mannich bases of arylidenepyridazinones as analgesic agents. , 1992, Journal of pharmaceutical sciences.

[7]  C. Torrance,et al.  Gastrointestinal damage associated with the use of nonsteroidal antiinflammatory drugs. , 1992, The New England journal of medicine.

[8]  V. D. Piaz,et al.  Reductive cleavage of isoxazolo[3,4-d]pyridazinones : a synthetic approach to various 4,5-functionalized 3(2H)-pyridazinones , 1991 .

[9]  D. Walsh,et al.  Prevention of opioid side effects. , 1990, Journal of pain and symptom management.

[10]  M. Sato,et al.  A new nonsteroidal analgesic-antiinflammatory agent. Synthesis and activity of 4-ethoxy-2-methyl-5-morpholino-3(2H)-pyridazinone and related compounds. , 1979, Journal of medicinal chemistry.

[11]  C. Wermuth Dérivés pyridaziniques présentant un intérêt thérapeutique. I. Revue générale et contribution personnelle. , 1965 .

[12]  F. Yoneda,et al.  Pyridazin-derivate. V. Synthese der Derivate des 6-Phenyl-3 (2H)-pyridazinons. , 1964 .

[13]  R. Cadmus,et al.  A Method for Evaluating both Non-Narcotic and Narcotic Analgesics , 1957, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.