Confocal Endomicroscopy: Instrumentation and Medical Applications

[1]  A Boyde,et al.  In Vivo Microscopy Using the Tandem Scanning Microscope a , 1986, Annals of the New York Academy of Sciences.

[2]  T. Wilson,et al.  Fibre-optic based confocal scanning microscopy with semiconductor laser excitation and detection , 1992 .

[3]  A. Gmitro,et al.  Confocal microscopy through a fiber-optic imaging bundle. , 1993, Optics letters.

[4]  Vivek Kaul,et al.  Confocal laser endomicroscopy. , 2009, Gastrointestinal endoscopy.

[5]  P. Corcuff,et al.  In vivo vision of the human skin with the tandem scanning microscope. , 1993, Dermatology.

[6]  R. Kiesslich,et al.  In vivo histology of Barrett's esophagus and associated neoplasia by confocal laser endomicroscopy. , 2005, Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association.

[7]  Michele Follen,et al.  Confocal microscopy: imaging cervical precancerous lesions. , 2005, Gynecologic oncology.

[8]  S. Kudo,et al.  Virtual histology of colorectal lesions using laser-scanning confocal microscopy. , 2003, Endoscopy.

[9]  R. Lotan,et al.  Laser scanning confocal microscopy of cervical tissue before and after application of acetic acid. , 2000, American journal of obstetrics and gynecology.

[10]  M. Harris,et al.  Fiber-optic laser scanning confocal microscope suitable for fluorescence imaging. , 1994, Applied optics.

[11]  R. Webb,et al.  In vivo confocal scanning laser microscopy of human skin II: advances in instrumentation and comparison with histology. , 1999, The Journal of investigative dermatology.

[12]  Michael Vieth,et al.  In vivo histology of Barrett's esophagus and associated neoplasia by confocal laser endomicroscopy. , 2006, Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association.

[13]  Rebecca Richards-Kortum,et al.  Oral premalignancy: New methods of detection and treatment , 2006, Current oncology reports.

[14]  R Richards-Kortum,et al.  Fiber confocal reflectance microscope (FCRM) for in-vivo imaging. , 2001, Optics express.

[15]  M. Vieth,et al.  Probe-based confocal laser endomicroscopy compared with standard four-quadrant biopsy for evaluation of neoplasia in Barrett’s esophagus , 2010, Endoscopy.

[16]  Rijk Schuetz,et al.  Electrostatically driven micromirrors for a miniaturized confocal laser scanning microscope , 1999, Photonics West - Micro and Nano Fabricated Electromechanical and Optical Components.

[17]  T Wilson,et al.  Confocal scanning optical microscope using single-mode fiber for signal detection. , 1991, Applied optics.

[18]  R. Kiesslich,et al.  Simultaneous confocal laser endomicroscopy and chromoendoscopy with topical cresyl violet. , 2009, Gastrointestinal endoscopy.

[19]  Alexander Meining,et al.  In vivo histopathology for detection of gastrointestinal neoplasia with a portable, confocal miniprobe: an examiner blinded analysis. , 2007, Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association.

[20]  Fiber-optic confocal microscope for biological imaging , 1998, Technical Digest. Summaries of Papers Presented at the Conference on Lasers and Electro-Optics. Conference Edition. 1998 Technical Digest Series, Vol.6 (IEEE Cat. No.98CH36178).

[21]  Robert T Kester,et al.  Low cost, high performance, self-aligning miniature optical systems. , 2009, Applied optics.

[22]  A. Mehta,et al.  In vivo mammalian brain imaging using one- and two-photon fluorescence microendoscopy. , 2004, Journal of neurophysiology.

[23]  Kenzi Murakami.  A miniature confocal optical scanning microscope for endoscopes , 2005, SPIE MOEMS-MEMS.

[24]  E. Vicaut,et al.  Fibered Confocal Fluorescence Microscopy (Cell-viZio™) Facilitates Extended Imaging in the Field of Microcirculation , 2004, Journal of Vascular Research.

[25]  R. Webb,et al.  Video-rate confocal scanning laser microscope for imaging human tissues in vivo. , 1999, Applied optics.

[26]  H. Miyajima,et al.  A miniature confocal optical microscope with MEMS gimbal scanner , 2003, TRANSDUCERS '03. 12th International Conference on Solid-State Sensors, Actuators and Microsystems. Digest of Technical Papers (Cat. No.03TH8664).

[27]  E. Cocker,et al.  Fiber-optic fluorescence imaging , 2005, Nature Methods.

[28]  Kung-Bin Sung,et al.  Fiber optic confocal reflectance microscopy: a new real-time technique to view nuclear morphology in cervical squamous epithelium in vivo. , 2003, Optics express.

[29]  D. Tank,et al.  A Miniature Head-Mounted Two-Photon Microscope High-Resolution Brain Imaging in Freely Moving Animals , 2001, Neuron.

[30]  Dae-Gab Gweon,et al.  Design of small confocal endo-microscopic probe working under multiwavelength environment , 2010, BiOS.

[31]  D. Madoff,et al.  Handheld histology-equivalent sectioning laser-scanning confocal optical microscope for interventional imaging , 2010, Biomedical microdevices.

[32]  A. Saftoiu,et al.  Confocal laser endomicroscopy of the colon. , 2010, Journal of gastrointestinal and liver diseases : JGLD.

[33]  R Richards-Kortum,et al.  Fiber-optic confocal microscopy using a spatial light modulator. , 2000, Optics letters.

[34]  Tomasz S. Tkaczyk,et al.  Design and evaluation of an ultra-slim objective for in-vivo deep optical biopsy , 2010, Optics express.

[35]  F. Helmchen,et al.  Ultra-compact fiber-optic two-photon microscope for functional fluorescence imaging in vivo. , 2008, Optics express.

[36]  B Bouma,et al.  A GRISM-based probe for spectrally encoded confocal microscopy. , 2003, Optics express.

[37]  O. Maeda,et al.  Confocal endomicroscopy in patients with ulcerative colitis , 2008, Journal of gastroenterology and hepatology.

[38]  R Richards-Kortum,et al.  Near real time in vivo fibre optic confocal microscopy: sub‐cellular structure resolved , 2002, Journal of microscopy.

[39]  Luke P. Lee,et al.  Micromachined transmissive scanning confocal microscope. , 2004, Optics letters.

[40]  C. Hartnick,et al.  Preliminary evaluation of noninvasive microscopic imaging techniques for the study of vocal fold development. , 2009, Journal of voice : official journal of the Voice Foundation.

[41]  R. Webb,et al.  Spectrally encoded confocal microscopy. , 1998, Optics letters.

[42]  Matthew D. Chidley,et al.  Design, assembly, and optical bench testing of a high-numerical-aperture miniature injection-molded objective for fiber-optic confocal reflectance microscopy. , 2006, Applied optics.

[43]  Calum MacAulay,et al.  Confocal microendoscopy with chromatic sectioning , 2003, SPIE BiOS.

[44]  W. Piyawattanametha,et al.  3-D Near-Infrared Fluorescence Imaging Using an MEMS-Based Miniature Dual-Axis Confocal Microscope , 2009, IEEE Journal of Selected Topics in Quantum Electronics.

[45]  C. Sheppard,et al.  Image formation in a fiber-optical confocal scanning microscope , 1991 .

[46]  Mathieu Salaün,et al.  Confocal fluorescence endomicroscopy of the human airways. , 2009, Proceedings of the American Thoracic Society.

[47]  A. Rouse,et al.  In vivo imaging of ovarian tissue using a novel confocal microlaparoscope. , 2010, American journal of obstetrics and gynecology.

[48]  Gordon S. Kino,et al.  Scanned optical fiber confocal microscope , 1994, Electronic Imaging.

[49]  Linas Giniunas,et al.  Scanning fibre-optic microscope , 1991 .

[50]  Thomas D. Wang,et al.  Miniature near-infrared dual-axes confocal microscope utilizing a two-dimensional microelectromechanical systems scanner. , 2007, Optics letters.

[51]  B Messerschmidt,et al.  Endoscope-compatible confocal microscope using a gradient index-lens system , 2001 .

[52]  E. Buscarini,et al.  Confocal laser endomicroscopy in celiac disease: description of findings in two cases , 2007, Endoscopy.

[53]  Andrew R. Rouse,et al.  Development and use of a confocal microendoscope for in-vivo histopathologic diagnosis , 2001, SPIE BiOS.

[54]  T Wilson,et al.  Direct-view fiber-optic confocal microscope. , 1994, Optics letters.

[55]  David L. Dickensheets,et al.  Requirements of MEMS membrane mirrors for focus adjustment and aberration correction in endoscopic confocal and optical coherence tomography imaging instruments , 2008 .

[56]  Rebecca R. Richards-Kortum,et al.  Fiber-optic confocal reflectance microscope with miniature objective for in vivo imaging of human tissues , 2002, IEEE Transactions on Biomedical Engineering.

[57]  Huilong Duan,et al.  Confocal fluorescence microendoscopy using a digital micro-mirror device , 2010, SPIE/COS Photonics Asia.

[58]  Richard M. Levenson,et al.  Point-of-Care Pathology with Miniature Microscopes , 2011, Analytical cellular pathology.

[59]  G. V. Rosmalen,et al.  Confocal compact scanning optical microscope based on compact disc technology. , 1991, Applied optics.

[60]  Robert T Kester,et al.  High numerical aperture microendoscope objective for a fiber confocal reflectance microscope. , 2007, Optics express.

[61]  Andreas Wree,et al.  Laser Scanning Microscopy of the Human Larynx Mucosa: A Preliminary, Ex Vivo Study , 2006, The Laryngoscope.

[62]  M Rajadhyaksha,et al.  Noninvasive Imaging of Human Oral Mucosa in Vivo by Confocal Reflectance Microscopy , 1999, The Laryngoscope.

[63]  R. Webb,et al.  In vivo confocal scanning laser microscopy of human skin: melanin provides strong contrast. , 1995, The Journal of investigative dermatology.

[64]  A. Polglase,et al.  Confocal laser endoscopy for diagnosing intraepithelial neoplasias and colorectal cancer in vivo. , 2004, Gastroenterology.

[65]  Thomas D. Wang,et al.  Dual-axis confocal microscope for high-resolution in vivo imaging. , 2003, Optics letters.

[66]  Charles P. Lin,et al.  In vivo confocal and multiphoton microendoscopy. , 2008, Journal of biomedical optics.

[67]  Y. Sabharwal,et al.  Slit-scanning confocal microendoscope for high-resolution in vivo imaging. , 1999, Applied optics.

[68]  H. D. Cavanagh,et al.  In vivo, real-time confocal imaging. , 1991, Journal of electron microscopy technique.

[69]  N Iftimia,et al.  Rapid wavelength-swept spectrally encoded confocal microscopy. , 2005, Optics express.

[70]  Carl Paterson,et al.  Adaptive phase compensation for ultracompact laser scanning endomicroscopy. , 2011, Optics letters.

[71]  Andrew V Biankin,et al.  In vivo confocal endomicroscopy in the diagnosis and evaluation of celiac disease. , 2008, Gastroenterology.

[72]  B E Bouma,et al.  Spectrally encoded miniature endoscopy. , 2002, Optics letters.

[73]  W M Petroll,et al.  In vivo confocal imaging: general principles and applications. , 1994, Scanning.

[74]  David L. Dickensheets,et al.  MOEMS deformable mirrors for focus control in vital microscopy , 2011 .

[75]  F. Lacombe,et al.  To see the unseeable: confocal miniprobes for routine microscopic imaging during endoscopy , 2007, SPIE BiOS.

[76]  Thomas D. Wang,et al.  Detection of colonic dysplasia in vivo using a targeted heptapeptide and confocal microendoscopy , 2008, Nature Medicine.

[77]  Nicholas Ayache,et al.  Towards Optical Biopsies with an Integrated Fibered Confocal Fluorescence Microscope , 2004, MICCAI.

[78]  A. Polglase,et al.  A fluorescence confocal endomicroscope for in vivo microscopy of the upper- and the lower-GI tract. , 2005, Gastrointestinal endoscopy.

[79]  Matthew D. Chidley,et al.  In vivo fiber-optic confocal reflectance microscope with an injection-molded plastic miniature objective lens. , 2005, Applied optics.

[80]  Andrew R. Rouse,et al.  Development of a fiber-optic confocal microendoscope for clinical endoscopy , 2002, SPIE BiOS.

[81]  R. Richards-Kortum,et al.  Fiber-optic confocal microscope using a MEMS scanner and miniature objective lens. , 2007, Optics express.

[82]  R. Juškaitis,et al.  Endoscope with optical sectioning capability. , 1993, Applied optics.

[83]  H. Dwight Cavanagh,et al.  The application of confocal microscopy to the study of living systems , 1993, Neuroscience & Biobehavioral Reviews.

[84]  C J Koester,et al.  Clinical microscopy of the cornea utilizing optical sectioning and a high-numerical-aperture objective. , 1993, Journal of the Optical Society of America. A, Optics and image science.

[85]  Ann M Gillenwater,et al.  Real‐time detection of epidermal growth factor receptor expression in fresh oral cavity biopsies using a molecular‐specific contrast agent , 2006, International journal of cancer.

[86]  F. Lacombe,et al.  Mauna Kea technologies' F400 prototype: a new tool for in vivo microscopic imaging during endoscopy , 2006, SPIE BiOS.

[87]  M. Schnitzer,et al.  In vivo fluorescence imaging with high-resolution microlenses , 2009, Nature Methods.

[88]  Michael Vieth,et al.  In vivo molecular imaging of colorectal cancer with confocal endomicroscopy by targeting epidermal growth factor receptor. , 2010, Gastroenterology.

[89]  Deepak Uttamchandani,et al.  A confocal micro-imaging system incorporating a thermally actuated two axis MEMS scanner , 2009, BiOS.

[90]  Oliver Stachs,et al.  Rigid confocal endoscopy for in vivo imaging of experimental oral squamous intra-epithelial lesions. , 2009, Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology.

[91]  Rimas Juskaitis,et al.  Endoscope with optical sectioning capability , 1994, Other Conferences.

[92]  Christopher H Contag,et al.  Dual-axes confocal microscopy with post-objective scanning and low-coherence heterodyne detection. , 2003, Optics letters.

[93]  M. Harris,et al.  Fibre optic confocal imaging (FOCI) for subsurface microscopy of the colon in vivo. , 1994, Journal of anatomy.

[94]  Shinji Tanaka,et al.  Optical biopsy of early gastroesophageal cancer by catheter-based reflectance-type laser-scanning confocal microscopy. , 2008, Journal of biomedical optics.

[95]  Andrew H. Beck,et al.  Dynamic real-time microscopy of the urinary tract using confocal laser endomicroscopy. , 2011, Urology.

[96]  A. Rouse,et al.  Multispectral imaging with a confocal microendoscope. , 2000, Optics letters.

[97]  David D Sampson,et al.  Deep-tissue access with confocal fluorescence microendoscopy through hypodermic needles. , 2011, Optics express.

[98]  Rebecca R. Richards-Kortum,et al.  An image model and segmentation algorithm for reflectance confocal images of in vivo cervical tissue , 2005, IEEE Transactions on Image Processing.

[99]  G. Kino,et al.  Silicon-micromachined scanning confocal optical microscope , 1998 .

[100]  D Yelin,et al.  Large area confocal microscopy. , 2007, Optics letters.

[101]  M. Descour,et al.  Design of a high-numerical-aperture miniature microscope objective for an endoscopic fiber confocal reflectance microscope. , 2002, Applied optics.

[102]  Tony Wilson,et al.  Real-Time White Light Reflection Confocal Microscopy Using a Fibre-Optic Bundle , 2006 .

[103]  Rebecca Richards-Kortum,et al.  Optical contrast agents and imaging systems for detection and diagnosis of cancer , 2008, International journal of cancer.

[104]  A. Rouse,et al.  Clinical confocal microlaparoscope for real-time in vivo optical biopsies. , 2009, Journal of biomedical optics.

[105]  J. Pyman,et al.  Detection of cervical intraepithelial neoplasia in vivo using confocal endomicroscopy , 2009, BJOG : an international journal of obstetrics and gynaecology.

[106]  Martin Goetz,et al.  Confocal endomicroscopy: a novel application for imaging of oral and oropharyngeal mucosa in human , 2010, European Archives of Oto-Rhino-Laryngology.

[107]  Proceedings of SPIE,et al.  Endoscopic Microscopy IV , 2009 .

[108]  A. Boyde,et al.  In vivo imaging of human teeth and skin using real-time confocal microscopy , 1991 .

[109]  Anthony A. Tanbakuchi,et al.  Surgical imaging catheter for confocal microendoscopy with advanced contrast delivery and focus systems , 2006, SPIE BiOS.

[110]  E. Cocker,et al.  In vivo brain imaging using a portable 3.9 gram two-photon fluorescence microendoscope. , 2005, Optics letters.

[111]  Tom Kamiel Magda Vercauteren,et al.  In vivo imaging of the bronchial wall microstructure using fibered confocal fluorescence microscopy. , 2007, American journal of respiratory and critical care medicine.

[112]  Q Wang,et al.  Differentiation of colonic polyps by confocal laser endomicroscopy. , 2011, Endoscopy.

[113]  Euiheon Chung,et al.  In vivo wide-area cellular imaging by side-view endomicroscopy , 2010, Nature Methods.

[114]  Christopher H Contag,et al.  Three-dimensional in vivo imaging by a handheld dual-axes confocal microscope. , 2008, Optics express.

[115]  Y. Hirooka,et al.  Confocal endomicroscopy for the diagnosis of gastric cancer in vivo , 2006, Endoscopy.

[116]  T. Wilson.  Image formation in two-mode fiber-based confocal microscopes , 1993 .

[117]  Xingde Li,et al.  Fiber-optic scanning two-photon fluorescence endoscope. , 2006, Optics letters.

[118]  Joseph C Liao,et al.  Optical biopsy of human bladder neoplasia with in vivo confocal laser endomicroscopy. , 2009, The Journal of urology.

[119]  R. Kiesslich,et al.  Diagnosing Helicobacter pylori in vivo by confocal laser endoscopy. , 2005, Gastroenterology.

[120]  T Dabbs,et al.  Fiber-optic confocal microscope: FOCON. , 1992, Applied optics.

[121]  Annette McWilliams,et al.  Confocal fluorescence microendoscopy of bronchial epithelium. , 2009, Journal of biomedical optics.

[122]  Benno H W Hendriks,et al.  High-resolution resonant and nonresonant fiber-scanning confocal microscope. , 2011, Journal of biomedical optics.

[123]  G S Kino,et al.  Micromachined scanning confocal optical microscope. , 1996, Optics letters.

[124]  M. Hashizume,et al.  Development and assessment of morphologic criteria for diagnosing gastric cancer using confocal endomicroscopy: an ex vivo and in vivo study , 2006, Endoscopy.

[125]  C. Gorecki,et al.  Electrostatically driven optical Z-axis scanner with thermally bonded glass microlens , 2010 .

[126]  Angelique Kano,et al.  Design and demonstration of a miniature catheter for a confocal microendoscope. , 2004, Applied optics.

[127]  M. Minsky.  Memoir on inventing the confocal scanning microscope , 1988 .

[128]  W. Semmler,et al.  Receptor-targeted optical imaging of tumors with near-infrared fluorescent ligands , 2001, Nature Biotechnology.

[129]  Kristen C. Maitland,et al.  In vivo imaging of oral neoplasia using a miniaturized fiber optic confocal reflectance microscope. , 2008, Oral oncology.

[130]  Hideo Tanaka,et al.  In situ fluorescence imaging of organs through compact scanning head for confocal laser microscopy. , 2005, Journal of biomedical optics.

[131]  Hyun Joon Shin,et al.  Single fiber confocal microscope with a two-axis gimbaled MEMS scanner for cellular imaging. , 2006, Optics express.

[132]  Brian C Wilson,et al.  Detection and treatment of dysplasia in Barrett's esophagus: a pivotal challenge in translating biophotonics from bench to bedside. , 2007, Journal of biomedical optics.