Genome-wide association study of obsessive-compulsive disorder

Y Wang | Dan J Stein | D V Conti | S Purcell | S E Stewart | S. E. Stewart | E Fournier | A J Fyer | J A Knowles | E H Cook | P Falkai | R. Delorme | M. Leboyer | E. Cook | S. Rauch | M. Turiel | B. Neale | H. Nicolini | H. Westenberg | D. Murphy | M. Jenike | S. Purcell | M. Cookson | J. Hardy | P. Falkai | W. Maier | B. Greenberg | E. Gamazon | A. Konkashbaev | D. Rosenberg | A. Fyer | C. Pato | D. Conti | J. Knowles | C. Pittenger | D. Posthuma | A. Crenshaw | J. Leckman | J. McCracken | D. Denys | E. Strengman | H. Grabe | J. Veenstra-VanderWeele | J. Kennedy | F. Macciardi | P. Heutink | M. Wagner | S. Walitza | G. Hanna | G. Nestadt | O. Bienvenu | M. Riddle | M. Grados | B. Cullen | D. Pauls | J. Wendland | D. Mirel | M. Bloch | D. Deforce | J. Gibbs | J. Fagerness | N. Lanzagorta | J. Smit | D. Black | P. Arnold | C. Lochner | S. Stewart | C. Mathews | L. Bellodi | S. Hemmings | D. Cath | L. Lennertz | S. Ruhrmann | J. Samuels | Y. Wang | C. Cappi | A. Sampaio | H. Vallada | A. Hounie | D. Yu | J. Scharf | P. Evans | L. Osiecki | L. McGrath | S. Haddad | J. Crane | D. Hezel | C. Illman | C. Mayerfeld | C. Liu | A. Pluzhnikov | A. Tikhomirov | C. Edlund | R. Moessner | M. Cavallini | M. Richter | A. Azzam | D. Chavira | E. Fournier | H. Garrido | B. Sheppard | P. Umaña | R. Blom | F. Nieuwerburgh | K. Egberts | T. Renner | E. C. Miguel | M. C. Rosário | B. Camarena | M. Pato | E. Voyiaziakis | V. Coric | V. Eapen | R. Ophoff | D. Cusi | F. Frau | A. Singleton | M. A. Parkin | N. Cox | B D Greenberg | M A Jenike | M Leboyer | R Delorme | W Maier | J L Kennedy | D L Pauls | G Nestadt | D L Murphy | S L Rauch | J Hardy | J F Leckman | J R Wendland | A Singleton | D J Stein | P Heutink | J T McCracken | J H Smit | C Pittenger | L Bellodi | D Posthuma | H Nicolini | S Haddad | D W Black | O J Bienvenu | S Walitza | J Veenstra-VanderWeele | F Macciardi | M A Riddle | H G M Westenberg | B M Neale | D Denys | E Voyiaziakis | C Liu | D B Mirel | D Deforce | M T Pato | C N Pato | R A Ophoff | J Samuels | M A Grados | B Cullen | D C Cath | M Wagner | H Vallada | S Ruhrmann | E R Gamazon | K Egberts | V Eapen | C A Mathews | M Turiel | B Camarena | E Strengman | D Yu | J M Scharf | J A Fagerness | P D Arnold | P D Evans | L Osiecki | L McGrath | J Crane | D Hezel | C Illman | C Mayerfeld | A Konkashbaev | A Pluzhnikov | A Tikhomirov | C K Edlund | R Moessner | H-J Grabe | L Lennertz | M C Cavallini | M A Richter | D Rosenberg | S M J Hemmings | C Lochner | A Azzam | D A Chavira | H Garrido | B Sheppard | P Umaña | R Blom | F Van Nieuwerburgh | T Renner | E C Miguel | C Cappi | A G Hounie | M Conceição do Rosário | A S Sampaio | N Lanzagorta | V Coric | M Bloch | D Cusi | F Frau | J R Gibbs | M R Cookson | A T Crenshaw | M A Parkin | G L Hanna | N Cox | J. Hardy | J. Kennedy | M. Parkin

[1]  S. E. Stewart,et al.  Genome-wide association study of Tourette Syndrome , 2012, Molecular Psychiatry.

[2]  Colm O'Dushlaine,et al.  INRICH: interval-based enrichment analysis for genome-wide association studies , 2012, Bioinform..

[3]  D. Rosenberg,et al.  The role of glutamate signaling in the pathogenesis and treatment of obsessive–compulsive disorder , 2012, Pharmacology Biochemistry and Behavior.

[4]  S Purcell,et al.  De novo CNV analysis implicates specific abnormalities of postsynaptic signalling complexes in the pathogenesis of schizophrenia , 2011, Molecular Psychiatry.

[5]  C. Pittenger,et al.  Glutamate abnormalities in obsessive compulsive disorder: neurobiology, pathophysiology, and treatment. , 2011, Pharmacology & therapeutics.

[6]  Anders D. Børglum,et al.  Genome-wide association study identifies five new schizophrenia loci , 2011, Nature Genetics.

[7]  S. Murray,et al.  Genomewide linkage analysis in Costa Rican families implicates chromosome 15q14 as a candidate region for OCD , 2011, Human Genetics.

[8]  F. Rijsdijk,et al.  A multivariate twin study of obsessive-compulsive symptom dimensions. , 2011, Archives of general psychiatry.

[9]  D. Stein,et al.  Investigating SAPAP3 variants in the etiology of obsessive-compulsive disorder and trichotillomania in the South African white population. , 2011, Comprehensive psychiatry.

[10]  Mary Goldman,et al.  The UCSC Genome Browser database: update 2011 , 2010, Nucleic Acids Res..

[11]  Margit Burmeister,et al.  Family-based association analysis to finemap bipolar linkage peak on chromosome 8q24 using 2,500 genotyped SNPs and 15,000 imputed SNPs. , 2010, Bipolar disorders.

[12]  L. Muglia,et al.  Temporal and Regional Regulation of Gene Expression by Calcium-Stimulated Adenylyl Cyclase Activity during Fear Memory , 2010, PloS one.

[13]  D. Altshuler,et al.  A map of human genome variation from population-scale sequencing , 2010, Nature.

[14]  Yun Li,et al.  METAL: fast and efficient meta-analysis of genomewide association scans , 2010, Bioinform..

[15]  A. Sajantila,et al.  Analysis of 9p24 and 11p12-13 regions in autism spectrum disorders: rs1340513 in the JMJD2C gene is associated with ASDs in Finnish sample , 2010, Psychiatric genetics.

[16]  J. Scharf,et al.  Copy number variation in Tourette syndrome , 2010, Neurology.

[17]  M. Eileen Dolan,et al.  Chemotherapeutic drug susceptibility associated SNPs are enriched in expression quantitative trait loci , 2010, Proceedings of the National Academy of Sciences.

[18]  Luigi Ferrucci,et al.  Abundant Quantitative Trait Loci Exist for DNA Methylation and Gene Expression in Human Brain , 2010, PLoS genetics.

[19]  F. O’Neill,et al.  Alternative Factor Models and Heritability of the Short Leyton Obsessional Inventory—Children’s Version , 2010, Journal of abnormal child psychology.

[20]  N. Cox,et al.  Trait-Associated SNPs Are More Likely to Be eQTLs: Annotation to Enhance Discovery from GWAS , 2010, PLoS genetics.

[21]  Tomas Drgon,et al.  Personalized Smoking Cessation: Interactions between Nicotine Dose, Dependence and Quit Success Genotype Score Uncorrected Proof Materials and Methods Study Design Uncorrected Proof , 2022 .

[22]  Wei Zhang,et al.  SCAN: SNP and copy number annotation , 2010, Bioinform..

[23]  Dan J Stein,et al.  The epidemiology of obsessive-compulsive disorder in the National Comorbidity Survey Replication , 2010, Molecular Psychiatry.

[24]  D. Collier,et al.  Interspecies Trait Genetics Reveals Association of Adcy8 with Mouse Avoidance Behavior and a Human Mood Disorder , 2009, Biological Psychiatry.

[25]  F. Richer,et al.  Association of intronic variants of the BTBD9 gene with Tourette syndrome. , 2009, Archives of neurology.

[26]  Pasko Rakic,et al.  Integration of neuronal clones in the radial cortical columns by EphA and ephrin-A signalling , 2009, Nature.

[27]  T. O'Connor,et al.  Normative childhood repetitive routines and obsessive compulsive symptomatology in 6-year-old twins. , 2009, Journal of child psychology and psychiatry, and allied disciplines.

[28]  Pall I. Olason,et al.  Common variants conferring risk of schizophrenia , 2009, Nature.

[29]  V. Willour,et al.  Sapap3 and pathological grooming in humans: Results from the OCD collaborative genetics study , 2009, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

[30]  P. Donnelly,et al.  A Flexible and Accurate Genotype Imputation Method for the Next Generation of Genome-Wide Association Studies , 2009, PLoS genetics.

[31]  S. Cichon,et al.  Genomewide association studies: history, rationale, and prospects for psychiatric disorders. , 2009, The American journal of psychiatry.

[32]  S. Potkin,et al.  Gene discovery through imaging genetics: identification of two novel genes associated with schizophrenia , 2009, Molecular Psychiatry.

[33]  D. Murphy,et al.  A haplotype containing quantitative trait loci for SLC1A1 gene expression and its association with obsessive-compulsive disorder. , 2009, Archives of general psychiatry.

[34]  M. Cuccaro,et al.  Multiple rare SAPAP3 missense variants in trichotillomania and OCD , 2009, Molecular Psychiatry.

[35]  S. Rauch,et al.  Evidence for potential relationship between SLC1A1 and a putative genetic linkage region on chromosome 14q to obsessive‐compulsive disorder with compulsive hoarding , 2008, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

[36]  Gary E. Swan,et al.  Systematic biological prioritization after a genome-wide association study: an application to nicotine dependence , 2008, Bioinform..

[37]  J. Haines,et al.  Fine mapping of the GLC1K juvenile primary open-angle glaucoma locus and exclusion of candidate genes , 2008, Molecular vision.

[38]  Stephanie E. Afful,et al.  Drug use and dependence in cocaine dependent subjects, community-based individuals, and their siblings. , 2008, Drug and alcohol dependence.

[39]  F. Dudbridge,et al.  Estimation of significance thresholds for genomewide association scans , 2008, Genetic epidemiology.

[40]  S. E. Stewart,et al.  Association of the SLC1A1 glutamate transporter gene and obsessive‐compulsive disorder , 2007, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

[41]  D. Dickel,et al.  Evidence for a Susceptibility Locus on Chromosome 10p15 in Early-Onset Obsessive-Compulsive Disorder , 2007, Biological Psychiatry.

[42]  Manuel A. R. Ferreira,et al.  PLINK: a tool set for whole-genome association and population-based linkage analyses. , 2007, American journal of human genetics.

[43]  S. Dudek,et al.  Cortico-striatal synaptic defects and OCD-like behaviours in Sapap3-mutant mice , 2007, Nature.

[44]  J. Leckman,et al.  Principal Components Analysis of Obsessive–Compulsive Disorder Symptoms in Children and Adolescents , 2007, Biological Psychiatry.

[45]  R. Delorme,et al.  A genetic family-based association study of OLIG2 in obsessive-compulsive disorder. , 2007, Archives of general psychiatry.

[46]  V. Willour,et al.  Significant linkage to compulsive hoarding on chromosome 14 in families with obsessive-compulsive disorder: results from the OCD Collaborative Genetics Study. , 2007, The American journal of psychiatry.

[47]  Scott F. Saccone,et al.  Novel genes identified in a high-density genome wide association study for nicotine dependence. , 2007, Human molecular genetics.

[48]  P. Defossez,et al.  Born to bind: the BTB protein–protein interaction domain , 2006, BioEssays : news and reviews in molecular, cellular and developmental biology.

[49]  Y Wang,et al.  Genomewide linkage scan for obsessive-compulsive disorder: evidence for susceptibility loci on chromosomes 3q, 7p, 1q, 15q, and 6q , 2006, Molecular Psychiatry.

[50]  D. Dickel,et al.  Association testing of the positional and functional candidate gene SLC1A1/EAAC1 in early-onset obsessive-compulsive disorder. , 2006, Archives of general psychiatry.

[51]  J. Kennedy,et al.  Glutamate transporter gene SLC1A1 associated with obsessive-compulsive disorder. , 2006, Archives of general psychiatry.

[52]  Bradley M. Hemminger,et al.  TAMAL: an integrated approach to choosing SNPs for genetic studies of human complex traits , 2006, Bioinform..

[53]  D. Boomsma,et al.  Twin studies on obsessive-compulsive disorder: a review. , 2005, Twin research and human genetics : the official journal of the International Society for Twin Studies.

[54]  C. Burge,et al.  Conserved Seed Pairing, Often Flanked by Adenosines, Indicates that Thousands of Human Genes are MicroRNA Targets , 2005, Cell.

[55]  M. Olivier.  A haplotype map of the human genome. , 2003, Nature.

[56]  M. Olivier.  A haplotype map of the human genome , 2003, Nature.

[57]  V. Willour,et al.  Replication study supports evidence for linkage to 9p24 in obsessive-compulsive disorder. , 2004, American journal of human genetics.

[58]  U. Suter,et al.  Neural membrane protein 35/Lifeguard is localized at postsynaptic sites and in dendrites. , 2002, Brain research. Molecular brain research.

[59]  B. Leventhal,et al.  Genome-wide linkage analysis of families with obsessive-compulsive disorder ascertained through pediatric probands. , 2002, American journal of medical genetics.

[60]  Tom H. Pringle,et al.  The human genome browser at UCSC. , 2002, Genome research.

[61]  J. Glowinski,et al.  A 19-kDa Protein Belonging to a New Family Is Expressed in the Golgi Apparatus of Neural Cells (*) , 1995, The Journal of Biological Chemistry.

[62]  Jennifer A. Pellowski,et al.  The National Institute on Alcohol Abuse and Alcoholism , 1995, Alcohol health and research world.

[63]  D. Blazer.  Research: Methods, Mechanisms, and Causes Introduction. , 2017, The American journal of psychiatry.

[64]  B. Sadock,et al.  Study Guide and Self-Examination Review for Kaplan & Sadock's Synopsis of Psychiatry , 1994 .

[65]  R. Kessler,et al.  The prevalence and distribution of major depression in a national community sample: the National Comorbidity Survey. , 1994, The American journal of psychiatry.

[66]  S. Sorenson,et al.  The epidemiology of obsessive-compulsive disorder in five US communities. , 1988, Archives of general psychiatry.

[67]  M. Tsuang,et al.  Clinical characteristics and family history in DSM-III obsessive-compulsive disorder. , 1986, The American journal of psychiatry.

[68]  T. Insel,et al.  Parents of patients with obsessive-compulsive disorder , 1983, Psychological Medicine.

[69]  A. Tellegen,et al.  Genetics and personality inventories: The limits of replication with twin data , 1978 .

[70]  C. Rosenberg,et al.  Familial Aspects of Obsessional Neurosis , 1967, British Journal of Psychiatry.

[71]  E. Kringlen.  Obsessional Neurotics , 1965, British Journal of Psychiatry.

[72]  E. Rudin.  [On the problem of compulsive disease with special reference to its hereditary relations]. , 1953, Archiv fur Psychiatrie und Nervenkrankheiten, vereinigt mit Zeitschrift fur die gesamte Neurologie und Psychiatrie.

[73]  F. W. Brown.  Heredity in the Psychoneuroses (Summary) , 1942, Proceedings of the Royal Society of Medicine.

[74]  A. Lewis.  Problems of Obsessional Illness , 1936 .