MnSOD overexpression confers cisplatin resistance in lung adenocarcinoma via the NF-κB/Snail/Bcl-2 pathway.

[1]  G. Sheu,et al.  Activation of NF-κB by SOD2 promotes the aggressiveness of lung adenocarcinoma by modulating NKX2-1-mediated IKKβ expression. , 2013, Carcinogenesis.

[2]  Wenlin Huang,et al.  Genetic and epigenetic down-regulation of microRNA-212 promotes colorectal tumor metastasis via dysregulation of MnSOD. , 2013, Gastroenterology.

[3]  G. Sheu,et al.  MnSOD Promotes Tumor Invasion via Upregulation of FoxM1–MMP2 Axis and Related with Poor Survival and Relapse in Lung Adenocarcinomas , 2012, Molecular Cancer Research.

[4]  Dara L Aisner,et al.  Molecular pathology of non-small cell lung cancer: a practical guide. , 2012, American journal of clinical pathology.

[5]  I. Park,et al.  Silencing of Twist1 sensitizes NSCLC cells to cisplatin via AMPK-activated mTOR inhibition , 2012, Cell Death and Disease.

[6]  Paulo A. S. Nuin,et al.  EMT transcription factors snail and slug directly contribute to cisplatin resistance in ovarian cancer , 2012, BMC Cancer.

[7]  Young Woo Kim,et al.  E-cadherin inhibits nuclear accumulation of Nrf2: implications for chemoresistance of cancer cells , 2012, Journal of Cell Science.

[8]  D. Feldser,et al.  Response and resistance to NF-κB inhibitors in mouse models of lung adenocarcinoma. , 2011, Cancer discovery.

[9]  J. Merlin,et al.  Regulation of the high basal expression of the manganese superoxide dismutase gene in aggressive breast cancer cells. , 2011, Free radical biology & medicine.

[10]  Kou-Juey Wu,et al.  Regulation of Excision Repair Cross-Complementation Group 1 by Snail Contributes to Cisplatin Resistance in Head and Neck Cancer , 2010, Clinical Cancer Research.

[11]  S. Kang,et al.  Expression of Bcl-2 predicts outcome in locally advanced non-small cell lung cancer patients treated with cisplatin-based concurrent chemoradiotherapy. , 2010, Lung cancer.

[12]  Y. Wu,et al.  TNF-α/NF-κB/Snail pathway in cancer cell migration and invasion , 2010, British Journal of Cancer.

[13]  D. Feldser,et al.  Requirement for NF-κB signalling in a mouse model of lung adenocarcinoma , 2009, Nature.

[14]  C. Dominici,et al.  Slug (SNAI2) Down-Regulation by RNA Interference Facilitates Apoptosis and Inhibits Invasive Growth in Neuroblastoma Preclinical Models , 2008, Clinical Cancer Research.

[15]  Razelle Kurzrock,et al.  Phase II Trial of Curcumin in Patients with Advanced Pancreatic Cancer , 2008, Clinical Cancer Research.

[16]  S. Nam,et al.  Nuclear factor‐κB dependency of doxorubicin sensitivity in gastric cancer cells is determined by manganese superoxide dismutase expression , 2008, Cancer science.

[17]  P. Leroy,et al.  Role of manganese superoxide dismutase on growth and invasive properties of human estrogen-independent breast cancer cells , 2008, Breast Cancer Research and Treatment.

[18]  L. Nelles,et al.  Activation of NF-κB by Akt upregulates Snail expression and induces epithelium mesenchyme transition , 2007, Oncogene.

[19]  L. Oberley,et al.  Overexpression of manganese or copper-zinc superoxide dismutase inhibits breast cancer growth. , 2006, Free radical biology & medicine.

[20]  A. Look,et al.  Slug Antagonizes p53-Mediated Apoptosis of Hematopoietic Progenitors by Repressing puma , 2005, Cell.

[21]  L. Behrend,et al.  Manganese Superoxide Dismutase Induces p53-Dependent Senescence in Colorectal Cancer Cells , 2005, Molecular and Cellular Biology.

[22]  W. Farrar,et al.  Epigenetic silencing of manganese superoxide dismutase (SOD-2) in KAS 6/1 human multiple myeloma cells increases cell proliferation , 2005, Cancer biology & therapy.

[23]  L. Oberley,et al.  Inhibition of Cell Growth by Overexpression of Manganese Superoxide Dismutase (MnSOD) in Human Pancreatic Carcinoma , 2004, Free radical research.

[24]  S. Nam,et al.  Manganese superoxide dismutase expression correlates with chemosensitivity in human gastric cancer cell lines. , 2003, Clinical cancer research : an official journal of the American Association for Cancer Research.

[25]  J. Crapo,et al.  Superoxide dismutases in the lung and human lung diseases. , 2003, American journal of respiratory and critical care medicine.

[26]  L. Oberley,et al.  Manganese Superoxide Dismutase-Mediated Gene Expression in Radiation-Induced Adaptive Responses , 2003, Molecular and Cellular Biology.

[27]  L. Oberley,et al.  The role of manganese superoxide dismutase in the growth of pancreatic adenocarcinoma. , 2003, Cancer research.

[28]  S. Catz,et al.  Transcriptional regulation of bcl-2 by nuclear factor κB and its significance in prostate cancer , 2001, Oncogene.

[29]  M. Scerrati,et al.  The level of manganese superoxide dismutase content is an independent prognostic factor for glioblastoma. Biological mechanisms and clinical implications , 2001, British Journal of Cancer.

[30]  C. Gélinas,et al.  The Rel/NF-κB Family Directly Activates Expression of the Apoptosis Inhibitor Bcl-xL , 2000, Molecular and Cellular Biology.

[31]  M. van Glabbeke,et al.  New guidelines to evaluate the response to treatment in solid tumors , 2000, Journal of the National Cancer Institute.

[32]  P. Meltzer,et al.  Increased manganese superoxide dismutase expression suppresses the malignant phenotype of human melanoma cells. , 1993, Proceedings of the National Academy of Sciences of the United States of America.

[33]  A. Jemal,et al.  Global Cancer Statistics , 2011 .

[34]  C Gélinas,et al.  The Rel/NF-kappaB family directly activates expression of the apoptosis inhibitor Bcl-x(L). , 2000, Molecular and cellular biology.

[35]  M Van Glabbeke,et al.  New guidelines to evaluate the response to treatment in solid tumors. European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of Canada. , 2000, Journal of the National Cancer Institute.

[36]  B. Zhou,et al.  Stabilization of Snail by NFk B Is Required for Inflammation-Induced Cell Migration and Invasion , 2022 .