Association between type 2 diabetes mellitus-related SNP variants and obesity traits in a Saudi population

[1]  Erik Ingelsson,et al.  Genome-wide association studies of obesity and metabolic syndrome , 2014, Molecular and Cellular Endocrinology.

[2]  S. Kwak,et al.  Genetics of type 2 diabetes and potential clinical implications , 2013, Archives of pharmacal research.

[3]  G. Gibson,et al.  Genetic risk prediction in a small cohort of healthy adults in Atlanta. , 2013, Genetics research.

[4]  Shicheng Guo,et al.  Quantitative assessment of the variation in IGF2BP2 gene and type 2 diabetes risk , 2012, Acta Diabetologica.

[5]  T. Ogihara,et al.  Deletion of CDKAL1 Affects High-Fat Diet–Induced Fat Accumulation and Glucose-Stimulated Insulin Secretion in Mice, Indicating Relevance to Diabetes , 2012, PloS one.

[6]  B. Caballero,et al.  Global gender disparities in obesity: a review. , 2012, Advances in nutrition.

[7]  N. Stefan,et al.  Allele Summation of Diabetes Risk Genes Predicts Impaired Glucose Tolerance in Female and Obese Individuals , 2012, PloS one.

[8]  H. Al-Hazzaa,et al.  Lifestyle factors associated with overweight and obesity among Saudi adolescents , 2012, BMC Public Health.

[9]  R. Loos,et al.  Genetic determinants of common obesity and their value in prediction. , 2012, Best practice & research. Clinical endocrinology & metabolism.

[10]  Yusuke Nakamura,et al.  Common variants at CDKAL1 and KLF9 are associated with body mass index in east Asian populations , 2012, Nature Genetics.

[11]  N. Martin,et al.  Genetic and Environmental Contributions to Weight, Height, and BMI from Birth to 19 Years of Age: An International Study of Over 12,000 Twin Pairs , 2012, PloS one.

[12]  Tajamul Hussain,et al.  Adiponectin gene polymorphisms (T45G and G276T), adiponectin levels and risk for metabolic diseases in an Arab population. , 2012, Gene.

[13]  G. Liao,et al.  Dendritically targeted Bdnf mRNA is essential for energy balance and response to leptin , 2012, Nature Network Boston.

[14]  F. Rasmussen,et al.  Increasing Genetic Variance of Body Mass Index during the Swedish Obesity Epidemic , 2011, PloS one.

[15]  Felix R. Day,et al.  Developments in Obesity Genetics in the Era of Genome-Wide Association Studies , 2011, Lifestyle Genomics.

[16]  Tien Yin Wong,et al.  Genome-wide association study in individuals of South Asian ancestry identifies six new type 2 diabetes susceptibility loci , 2011, Nature Genetics.

[17]  D. Clegg,et al.  Obesity, insulin resistance and diabetes: sex differences and role of oestrogen receptors , 2011, Acta physiologica.

[18]  G. Chrousos,et al.  Diabetes mellitus type 2 and other chronic non-communicable diseases in the central region, Saudi Arabia (riyadh cohort 2): a decade of an epidemic , 2011, BMC medicine.

[19]  J. Florez,et al.  Association testing of TCF7L2 polymorphisms with type 2 diabetes in multi-ethnic youth , 2011, Diabetologia.

[20]  Donald W. Bowden,et al.  Resequencing and Analysis of Variation in the TCF7L2 Gene in African Americans Suggests That SNP rs7903146 Is the Causal Diabetes Susceptibility Variant , 2011, Diabetes.

[21]  J. Hebebrand,et al.  Chipping Away the ‘Missing Heritability’: GIANT Steps Forward in the Molecular Elucidation of Obesity – but Still Lots to Go , 2010, Obesity Facts.

[22]  Ayellet V. Segrè,et al.  Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis , 2010, Nature Genetics.

[23]  Jean Tichet,et al.  Genetic variant near IRS1 is associated with type 2 diabetes, insulin resistance and hyperinsulinemia , 2009, Nature Genetics.

[24]  L. Chuang,et al.  Genetic variants of TCF7L2 are associated with insulin resistance and related metabolic phenotypes in Taiwanese adolescents and Caucasian young adults. , 2009, The Journal of clinical endocrinology and metabolism.

[25]  C. Fox,et al.  TCF7L2 variants are associated with increased proinsulin/insulin ratios but not obesity traits in the Framingham Heart Study , 2009, Diabetologia.

[26]  T. Hansen,et al.  SNPs in KCNQ1 are associated with susceptibility to type 2 diabetes in East Asian and European populations , 2008, Nature Genetics.

[27]  N. Al-Daghri,et al.  Weak or no association of TCF7L2 variants with Type 2 diabetes risk in an Arab population , 2008, BMC Medical Genetics.

[28]  M. McCarthy,et al.  Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes , 2008, Nature Genetics.

[29]  Peter Almgren,et al.  Mechanisms by which common variants in the TCF7L2 gene increase risk of type 2 diabetes. , 2007, The Journal of clinical investigation.

[30]  J. Gulcher,et al.  A variant in CDKAL1 influences insulin response and risk of type 2 diabetes , 2007, Nature Genetics.

[31]  G. Abecasis,et al.  Supporting Online Material Materials and Methods Figs. S1 to S8 Tables S1 to S10 References a Genome-wide Association Study of Type 2 Diabetes in Finns Detects Multiple Susceptibility Variants , 2022 .

[32]  Beverley Balkau,et al.  Variation in FTO contributes to childhood obesity and severe adult obesity , 2007, Nature Genetics.

[33]  M. McCarthy,et al.  Replication of Genome-Wide Association Signals in UK Samples Reveals Risk Loci for Type 2 Diabetes , 2007, Science.

[34]  James Strait,et al.  Genome-Wide Association Scan Shows Genetic Variants in the FTO Gene Are Associated with Obesity-Related Traits , 2007, PLoS genetics.

[35]  M. Jarvelin,et al.  A Common Variant in the FTO Gene Is Associated with Body Mass Index and Predisposes to Childhood and Adult Obesity , 2007, Science.

[36]  T. Hudson,et al.  A genome-wide association study identifies novel risk loci for type 2 diabetes , 2007, Nature.

[37]  Adrian V. Lee,et al.  Mammary Tumorigenesis and Metastasis Caused by Overexpression of Insulin Receptor Substrate 1 (IRS-1) or IRS-2 , 2006, Molecular and Cellular Biology.

[38]  D. Clayton,et al.  Population structure, differential bias and genomic control in a large-scale, case-control association study , 2005, Nature Genetics.

[39]  E. Lander,et al.  Meta-analysis of genetic association studies supports a contribution of common variants to susceptibility to common disease , 2003, Nature Genetics.

[40]  J. Hebebrand,et al.  Epidemic obesity: are genetic factors involved via increased rates of assortative mating? , 2000, International Journal of Obesity.

[41]  F. Nielsen,et al.  A Family of Insulin-Like Growth Factor II mRNA-Binding Proteins Represses Translation in Late Development , 1999, Molecular and Cellular Biology.

[42]  Ellen Kampman,et al.  Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity , 2009, Nature Genetics.