Phosphorylation of serine 2 within the RNA polymerase II C-terminal domain couples transcription and 3' end processing.

[1]  N. Krogan,et al.  Transitions in RNA polymerase II elongation complexes at the 3′ ends of genes , 2004, The EMBO journal.

[2]  J. Lis,et al.  Coordination of transcription, RNA processing, and surveillance by P-TEFb kinase on heat shock genes. , 2004, Molecular cell.

[3]  M. Keogh,et al.  Bur1 Kinase Is Required for Efficient Transcription Elongation by RNA Polymerase II , 2003, Molecular and Cellular Biology.

[4]  V. Quesada,et al.  FY Is an RNA 3′ End-Processing Factor that Interacts with FCA to Control the Arabidopsis Floral Transition , 2003, Cell.

[5]  G. Braus,et al.  Polyadenylation of rRNA- and tRNA-based yeast transcripts cleaved by internal ribozyme activity , 2003, Current Genetics.

[6]  J. Yates,et al.  Dual Roles for Spt5 in Pre-mRNA Processing and Transcription Elongation Revealed by Identification of Spt5-Associated Proteins , 2003, Molecular and Cellular Biology.

[7]  K. Lund,et al.  Srb10/Cdk8 regulates yeast filamentous growth by phosphorylating the transcription factor Ste12 , 2003, Nature.

[8]  A. Greenleaf,et al.  The RNA polymerase II CTD kinase CTDK-I affects pre-mRNA 3' cleavage/polyadenylation through the processing component Pti1p. , 2002, Molecular cell.

[9]  G. Cagney,et al.  RNA Polymerase II Elongation Factors of Saccharomyces cerevisiae: a Targeted Proteomics Approach , 2002, Molecular and Cellular Biology.

[10]  G. Prelich,et al.  Activation of the Bur1-Bur2 Cyclin-Dependent Kinase Complex by Cak1 , 2002, Molecular and Cellular Biology.

[11]  Kevin Struhl,et al.  TREX is a conserved complex coupling transcription with messenger RNA export , 2002, Nature.

[12]  D. Licatalosi,et al.  Functional interaction of yeast pre-mRNA 3' end processing factors with RNA polymerase II. , 2002, Molecular cell.

[13]  M. Rosbash,et al.  T7 RNA polymerase-directed transcripts are processed in yeast and link 3' end formation to mRNA nuclear export. , 2002, RNA.

[14]  S. Squazzo,et al.  The Paf1 complex physically and functionally associates with transcription elongation factors in vivo , 2002, The EMBO journal.

[15]  A. Furger,et al.  Integrating mRNA Processing with Transcription , 2002, Cell.

[16]  P. Bork,et al.  Functional organization of the yeast proteome by systematic analysis of protein complexes , 2002, Nature.

[17]  Gary D Bader,et al.  Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry , 2002, Nature.

[18]  J. Greenblatt,et al.  Opposing effects of Ctk1 kinase and Fcp1 phosphatase at Ser 2 of the RNA polymerase II C-terminal domain. , 2001, Genes & development.

[19]  D. Lindstrom,et al.  Genetic interactions of Spt4-Spt5 and TFIIS with the RNA polymerase II CTD and CTD modifying enzymes in Saccharomyces cerevisiae. , 2001, Genetics.

[20]  B. Séraphin,et al.  The tandem affinity purification (TAP) method: a general procedure of protein complex purification. , 2001, Methods.

[21]  G. Hartzog,et al.  Phosphorylation of the RNA Polymerase II Carboxy-Terminal Domain by the Bur1 Cyclin-Dependent Kinase , 2001, Molecular and Cellular Biology.

[22]  R. Young,et al.  Negative regulation of Gcn4 and Msn2 transcription factors by Srb10 cyclin-dependent kinase. , 2001, Genes & development.

[23]  G. Jona,et al.  Involvement of yeast carboxy-terminal domain kinase I (CTDK-I) in transcription elongation in vivo. , 2001, Gene.

[24]  Krzysztof Sliwa,et al.  Functions of WW domains in the nucleus , 2001, FEBS letters.

[25]  L. Poon,et al.  Messenger RNAs that are not synthesized by RNA polymerase II can be 3′ end cleaved and polyadenylated , 2000, EMBO reports.

[26]  E. Cho,et al.  Different phosphorylated forms of RNA polymerase II and associated mRNA processing factors during transcription. , 2000, Genes & development.

[27]  D. Bentley,et al.  Dynamic association of capping enzymes with transcribing RNA polymerase II. , 2000, Genes & development.

[28]  Aaron J. Shatkin,et al.  The ends of the affair: Capping and polyadenylation , 2000, Nature Structural Biology.

[29]  K. Yamamoto,et al.  The glucocorticoid receptor inhibits NFkappaB by interfering with serine-2 phosphorylation of the RNA polymerase II carboxy-terminal domain. , 2000, Genes & development.

[30]  D. Reinberg,et al.  TFIIH is negatively regulated by cdk8-containing mediator complexes , 2000, Nature.

[31]  N. Proudfoot,et al.  Balancing transcriptional interference and initiation on the GAL7 promoter of Saccharomyces cerevisiae. , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[32]  J. Manley,et al.  RNA polymerase II and the integration of nuclear events. , 2000, Genes & development.

[33]  D. Price.  P-TEFb, a Cyclin-Dependent Kinase Controlling Elongation by RNA Polymerase II , 2000, Molecular and Cellular Biology.

[34]  C. Moore,et al.  Kin28, the TFIIH-Associated Carboxy-Terminal Domain Kinase, Facilitates the Recruitment of mRNA Processing Machinery to RNA Polymerase II , 2000, Molecular and Cellular Biology.

[35]  B. Séraphin,et al.  A generic protein purification method for protein complex characterization and proteome exploration , 1999, Nature Biotechnology.

[36]  J. Greenblatt,et al.  GAL4 is regulated by the RNA polymerase II holoenzyme-associated cyclin-dependent protein kinase SRB10/CDK8. , 1999, Molecular cell.

[37]  Hiroshi Handa,et al.  NELF, a Multisubunit Complex Containing RD, Cooperates with DSIF to Repress RNA Polymerase II Elongation , 1999, Cell.

[38]  C. Ho,et al.  Distinct roles for CTD Ser-2 and Ser-5 phosphorylation in the recruitment and allosteric activation of mammalian mRNA capping enzyme. , 1999, Molecular cell.

[39]  M. Swanson,et al.  Control of cleavage site selection during mRNA 3′ end formation by a yeast hnRNP , 1998, The EMBO journal.

[40]  J. Manley,et al.  Levels of polyadenylation factor CstF-64 control IgM heavy chain mRNA accumulation and other events associated with B cell differentiation. , 1998, Molecular cell.

[41]  Michael R. Green,et al.  Dissecting the Regulatory Circuitry of a Eukaryotic Genome , 1998, Cell.

[42]  E. Cho,et al.  Allosteric interactions between capping enzyme subunits and the RNA polymerase II carboxy-terminal domain. , 1998, Genes & development.

[43]  C. Dieckmann,et al.  Regulation of poly(A) site choice of several yeast mRNAs. , 1998, Nucleic acids research.

[44]  J. Manley,et al.  RNA polymerase II is an essential mRNA polyadenylation factor , 1998, Nature.

[45]  R. Young,et al.  Temporal regulation of RNA polymerase II by Srb10 and Kin28 cyclin-dependent kinases. , 1998, Molecular cell.

[46]  E. Mandart,et al.  Effects of mutations in the Saccharomyces cerevisiae RNA14 gene on the abundance and polyadenylation of its transcripts , 1998, Molecular and General Genetics MGG.

[47]  K. Yano,et al.  DSIF, a novel transcription elongation factor that regulates RNA polymerase II processivity, is composed of human Spt4 and Spt5 homologs. , 1998, Genes & development.

[48]  E. Cho,et al.  mRNA capping enzyme is recruited to the transcription complex by phosphorylation of the RNA polymerase II carboxy-terminal domain. , 1997, Genes & development.

[49]  D. Reinberg,et al.  Mammalian capping enzyme complements mutant Saccharomyces cerevisiae lacking mRNA guanylyltransferase and selectively binds the elongating form of RNA polymerase II. , 1997, Proceedings of the National Academy of Sciences of the United States of America.

[50]  Marco M. Kessler,et al.  Hrp1, a sequence-specific RNA-binding protein that shuttles between the nucleus and the cytoplasm, is required for mRNA 3'-end formation in yeast. , 1997, Genes & development.

[51]  G. Edwalds-Gilbert,et al.  Alternative poly(A) site selection in complex transcription units: means to an end? , 1997, Nucleic acids research.

[52]  M. Wickens,et al.  The C-terminal domain of RNA polymerase II couples mRNA processing to transcription , 1997, Nature.

[53]  R. Conaway,et al.  The RNA polymerase II general elongation factors. , 1996, Trends in biochemical sciences.

[54]  R. Parker,et al.  Effects of mutations in the Saccharomyces cerevisiae RNA14, RNA15, and PAP1 genes on polyadenylation in vivo , 1995, Molecular and cellular biology.

[55]  J. Corden,et al.  Construction and analysis of yeast RNA polymerase II CTD deletion and substitution mutations. , 1995, Genetics.

[56]  J. M. Lee,et al.  CTD kinase large subunit is encoded by CTK1, a gene required for normal growth of Saccharomyces cerevisiae. , 1991, Gene expression.

[57]  J. Corden.  Tails of RNA polymerase II. , 1990, Trends in biochemical sciences.

[58]  J. Greenblatt,et al.  Opposing effects of Ctk 1 kinase and Fcp 1 phosphatase at Ser 2 of the RNA polymerase II C-terminal domain , 2001 .

[59]  D. Bushnell,et al.  The Med proteins of yeast and their function through the RNA polymerase II carboxy-terminal domain. , 1998, Genes & development.