Combinatorial alanine-scanning.
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[1] G. P. Smith,et al. Filamentous fusion phage: novel expression vectors that display cloned antigens on the virion surface. , 1985, Science.
[2] J. Wells,et al. Comparison of a structural and a functional epitope. , 1993, Journal of molecular biology.
[3] M. Arkin,et al. Probing the importance of second sphere residues in an esterolytic antibody by phage display. , 1998, Journal of molecular biology.
[4] V. Petrenko,et al. Phage Display. , 1997, Chemical reviews.
[5] J. Kirsch,et al. Energetic analysis of an antigen/antibody interface: Alanine scanning mutagenesis and double mutant cycles on the hyhel‐10/lysozyme interaction , 1999, Protein science : a publication of the Protein Society.
[6] P. Schimmel,et al. An RNA binding site in a tRNA synthetase with a reduced set of amino acids. , 1994, Biochemistry.
[7] R. Myers,et al. A general method for saturation mutagenesis of cloned DNA fragments. , 1985, Science.
[8] J. Wells,et al. High-resolution epitope mapping of hGH-receptor interactions by alanine-scanning mutagenesis. , 1989, Science.
[9] B. Matthews,et al. Folding and function of a T4 lysozyme containing 10 consecutive alanines illustrate the redundancy of information in an amino acid sequence. , 1992, Proceedings of the National Academy of Sciences of the United States of America.
[10] James C. Hu,et al. Probing the roles of residues at the e and g positions of the GCN4 leucine zipper by combinatorial mutagenesis , 1993, Protein science : a publication of the Protein Society.
[11] T. Clackson,et al. A hot spot of binding energy in a hormone-receptor interface , 1995, Science.
[12] J. Wells,et al. Additivity of mutational effects in proteins. , 1990, Biochemistry.
[13] K Schulten,et al. VMD: visual molecular dynamics. , 1996, Journal of molecular graphics.
[14] B. Matthews,et al. Alanine scanning mutagenesis of the alpha-helix 115-123 of phage T4 lysozyme: effects on structure, stability and the binding of solvent. , 1995, Journal of molecular biology.
[15] T. Clackson,et al. Structural and functional analysis of the 1:1 growth hormone:receptor complex reveals the molecular basis for receptor affinity. , 1998, Journal of molecular biology.
[16] H. Lowman,et al. Total alanine-scanning mutagenesis of insulin-like growth factor I (IGF-I) identifies differential binding epitopes for IGFBP-1 and IGFBP-3. , 1999, Biochemistry.
[17] W. Lim,et al. Deciphering the message in protein sequences: tolerance to amino acid substitutions. , 1990, Science.
[18] C. Ampe,et al. A Phage Display Technique for a Fast, Sensitive, and Systematic Investigation of Protein–Protein Interactions , 1997, Journal of protein chemistry.
[19] Codon-based combinatorial alanine scanning site-directed mutagenesis: design, implementation, and polymerase chain reaction screening. , 1995, Analytical biochemistry.
[20] G. Weiss,et al. Rapid mapping of protein functional epitopes by combinatorial alanine scanning. , 2000, Proceedings of the National Academy of Sciences of the United States of America.
[21] S. Sidhu. Phage display in pharmaceutical biotechnology. , 2000, Current opinion in biotechnology.
[22] R. Hodges,et al. Synthetic study of the effect of tyrosine at position 120 of ribonuclease. , 2009, International journal of peptide and protein research.
[23] C. Gibbs,et al. Identification of electrostatic interactions that determine the phosphorylation site specificity of the cAMP-dependent protein kinase. , 1991, Biochemistry.
[24] R. Sauer,et al. Additivity of mutant effects assessed by binomial mutagenesis. , 1993, Proceedings of the National Academy of Sciences of the United States of America.
[25] E A Merritt,et al. Raster3D: photorealistic molecular graphics. , 1997, Methods in enzymology.
[26] J. Wells,et al. Systematic mutational analyses of protein-protein interfaces. , 1991, Methods in enzymology.
[27] Robert T. Sauer,et al. Protein stability effects of a complete set of alanine substitutions in Arc repressor , 1994, Nature Structural Biology.
[28] Analysis of receptor/ligand interactions using whole-molecule randomly-mutated ligand libraries. , 2000, Journal of immunological methods.
[29] D Altschuh,et al. Functional mapping of conserved residues located at the VL and VH domain interface of a Fab. , 1996, Journal of molecular biology.
[30] A. Fersht,et al. Hydrogen bonding and biological specificity analysed by protein engineering , 1985, Nature.
[31] Diversified sequences of peptide epitope for same-RNA recognition. , 1993, Proceedings of the National Academy of Sciences of the United States of America.
[32] R. Sauer,et al. Tolerance of Arc repressor to multiple-alanine substitutions. , 1999, Proceedings of the National Academy of Sciences of the United States of America.
[33] L. Presta,et al. Mapping the CD4 binding site for human immunodeficiency virus by alanine-scanning mutagenesis. , 1990, Proceedings of the National Academy of Sciences of the United States of America.
[34] I. Lasters,et al. Epitope mapping by negative selection of randomized antigen libraries displayed on filamentous phage. , 1997, Journal of molecular biology.
[35] G. Georgiou,et al. In vitro scanning saturation mutagenesis of all the specificity determining residues in an antibody binding site. , 1999, Protein engineering.
[36] Jeffrey Miller,et al. Genetic Studies of Lac Repressor: 4000 Single Amino Acid Substitutions and Analysis of the Resulting Phenotypes on the Basis of the Protein Structure , 1996, German Conference on Bioinformatics.