论文信息 - Discovery of (R,E)-N-(7-Chloro-1-(1-[4-(dimethylamino)but-2-enoyl]azepan-3-yl)-1H-benzo[d]imidazol-2-yl)-2-methylisonicotinamide (EGF816), a Novel, Potent, and WT Sparing Covalent Inhibitor of Oncogenic (L858R, ex19del) and Resistant (T790M) EGFR Mutants for the Treatment of EGFR Mutant Non-Small-Ce - 字舞流文

Discovery of (R,E)-N-(7-Chloro-1-(1-[4-(dimethylamino)but-2-enoyl]azepan-3-yl)-1H-benzo[d]imidazol-2-yl)-2-methylisonicotinamide (EGF816), a Novel, Potent, and WT Sparing Covalent Inhibitor of Oncogenic (L858R, ex19del) and Resistant (T790M) EGFR Mutants for the Treatment of EGFR Mutant Non-Small-Ce

Chun Xing Li | S. Bender | G. Spraggon | S. Kasibhatla | M. Didonato | D. Mason | R. Epple | B. Bursulaya | J. Isbell | T. Marsilje | J. Juarez | Yong Jia | Jie Li | P. Michellys | Y. Long | R. Fong | Gérald Lelais | Kevin Johnson | T. Groessl | Jaganmohan R. Anumolu | Perry Gordon | M. Manuia | Sangamesh E Badiger | Matthew H. Mcneill | Wenshuo Lu | Bei Chen | Jose C. Juarez | Mari Manuia