Epigenetic modifications and human disease

[1]  Dirk Schübeler,et al.  Tackling the epigenome: challenges and opportunities for collaboration , 2010, Nature Biotechnology.

[2]  A. Meissner Epigenetic modifications in pluripotent and differentiated cells , 2010, Nature Biotechnology.

[3]  M. Esteller,et al.  Disrupted microRNA expression caused by Mecp2 loss in a mouse model of Rett syndrome , 2010, Epigenetics.

[4]  T. Mikkelsen,et al.  The NIH Roadmap Epigenomics Mapping Consortium , 2010, Nature Biotechnology.

[5]  J. Dekker,et al.  Genomics tools for the unraveling of chromosome architecture , 2010, Nature Biotechnology.

[6]  Peter A. Jones,et al.  Epigenetic Modifications as Therapeutic Targets , 2010, Nature Biotechnology.

[7]  Yi Zhang,et al.  Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification , 2010, Nature.

[8]  R. Voll,et al.  Apoptosis-induced histone H3 methylation is targeted by autoantibodies in systemic lupus erythematosus , 2010, Annals of the rheumatic diseases.

[9]  Irving L. Weissman,et al.  A comprehensive methylome map of lineage commitment from hematopoietic progenitors , 2010, Nature.

[10]  N. Reich,et al.  The Inherent Processivity of the Human de Novo Methyltransferase 3A (DNMT3A) Is Enhanced by DNMT3L* , 2010, The Journal of Biological Chemistry.

[11]  A. Khalil,et al.  Nucleosome occupancy landscape and dynamics at mouse recombination hotspots , 2010, EMBO reports.

[12]  C. Allis,et al.  Covalent histone modifications — miswritten, misinterpreted and mis-erased in human cancers , 2010, Nature Reviews Cancer.

[13]  Manolis Kellis,et al.  Discovery and characterization of chromatin states for systematic annotation of the human genome , 2010, Nature Biotechnology.

[14]  Yuanjia Tang,et al.  MicroRNA-21 and MicroRNA-148a Contribute to DNA Hypomethylation in Lupus CD4+ T Cells by Directly and Indirectly Targeting DNA Methyltransferase 1 , 2010, The Journal of Immunology.

[15]  Jan Vrbsky,et al.  siRNA–Mediated Methylation of Arabidopsis Telomeres , 2010, PLoS genetics.

[16]  M. Pellegrini,et al.  Relationship between nucleosome positioning and DNA methylation , 2010, Nature.

[17]  E. Ashley,et al.  Chromatin regulation by Brg1 underlies heart muscle development and disease , 2010, Nature.

[18]  Luigi Ferrucci,et al.  Abundant Quantitative Trait Loci Exist for DNA Methylation and Gene Expression in Human Brain , 2010, PLoS genetics.

[19]  N. Tommerup,et al.  A Functional Link between the Histone Demethylase PHF8 and the Transcription Factor ZNF711 in X-Linked Mental Retardation , 2010, Molecular cell.

[20]  Robert S. Illingworth,et al.  CpG islands influence chromatin structure via the CpG-binding protein Cfp1 , 2010, Nature.

[21]  A. Wutz,et al.  X inactivation and disease. , 2010, Seminars in cell & developmental biology.

[22]  Charles W. Melnyk,et al.  siRNAs and DNA methylation: seedy epigenetics. , 2010, Trends in plant science.

[23]  Howard Y. Chang,et al.  Long noncoding RNA HOTAIR reprograms chromatin state to promote cancer metastasis , 2010, Nature.

[24]  Chia-Lin Wei,et al.  Dynamic changes in the human methylome during differentiation. , 2010, Genome research.

[25]  B. Blencowe,et al.  Regulation of Alternative Splicing by Histone Modifications , 2010, Science.

[26]  P. Laird Principles and challenges of genome-wide DNA methylation analysis , 2010, Nature Reviews Genetics.

[27]  Julia A. Lasserre,et al.  Histone modification levels are predictive for gene expression , 2010, Proceedings of the National Academy of Sciences.

[28]  Fatima Al-Shahrour,et al.  Changes in the pattern of DNA methylation associate with twin discordance in systemic lupus erythematosus. , 2010, Genome research.

[29]  T. Down,et al.  Differential DNA Methylation Correlates with Differential Expression of Angiogenic Factors in Human Heart Failure , 2010, PloS one.

[30]  G. Crabtree,et al.  Chromatin remodelling during development , 2010, Nature.

[31]  Miguel Alaminos,et al.  Epigenetic inactivation of the Sotos overgrowth syndrome gene histone methyltransferase NSD1 in human neuroblastoma and glioma , 2009, Proceedings of the National Academy of Sciences.

[32]  Martin J. Aryee,et al.  Differential methylation of tissue- and cancer-specific CpG island shores distinguishes human induced pluripotent stem cells, embryonic stem cells and fibroblasts , 2009, Nature Genetics.

[33]  F. Holsboer,et al.  Dynamic DNA methylation programs persistent adverse effects of early-life stress , 2009, Nature Neuroscience.

[34]  E. Ballestar,et al.  Impaired recruitment of the histone methyltransferase DOT1L contributes to the incomplete reactivation of tumor suppressor genes upon DNA demethylation , 2009, Oncogene.

[35]  Lee E. Edsall,et al.  Human DNA methylomes at base resolution show widespread epigenomic differences , 2009, Nature.

[36]  Gurpreet W. Tang,et al.  Systematic sequencing of renal carcinoma reveals inactivation of histone modifying genes , 2009, Nature.

[37]  Peter A. Jones,et al.  Rethinking how DNA methylation patterns are maintained , 2009, Nature Reviews Genetics.

[38]  Manel Esteller,et al.  Epigenetic mechanisms in neurological diseases: genes, syndromes, and therapies , 2009, The Lancet Neurology.

[39]  A. Sharrocks Faculty Opinions recommendation of JAK2 phosphorylates histone H3Y41 and excludes HP1alpha from chromatin. , 2009 .

[40]  J. Hewitt Faculty Opinions recommendation of Specific loss of histone H3 lysine 9 trimethylation and HP1gamma/cohesin binding at D4Z4 repeats is associated with facioscapulohumeral dystrophy (FSHD). , 2009 .

[41]  Andrew J. Bannister,et al.  JAK2 phosphorylates histone H3Y41 and excludes HP1α from chromatin , 2009, Nature.

[42]  T. Hothorn,et al.  Histone macroH2A isoforms predict the risk of lung cancer recurrence , 2009, Oncogene.

[43]  R. Feil,et al.  Chromatin mechanisms in genomic imprinting , 2009, Mammalian Genome.

[44]  K. Dewar,et al.  Allele-specific chromatin remodeling in the ZPBP2/GSDMB/ORMDL3 locus associated with the risk of asthma and autoimmune disease. , 2009, American journal of human genetics.

[45]  T. Rauch,et al.  Insulin Gene Expression Is Regulated by DNA Methylation , 2009, PloS one.

[46]  B. Cairns The logic of chromatin architecture and remodelling at promoters , 2009, Nature.

[47]  Dustin E. Schones,et al.  Genome-wide Mapping of HATs and HDACs Reveals Distinct Functions in Active and Inactive Genes , 2009, Cell.

[48]  S. Goodman,et al.  Sensitive digital quantification of DNA methylation in clinical samples , 2009, Nature Biotechnology.

[49]  M. Turunen,et al.  Epigenetics and atherosclerosis. , 2009, Biochimica et biophysica acta.

[50]  Madelaine Gogol,et al.  Global Analysis of H3K4 Methylation Defines MLL Family Member Targets and Points to a Role for MLL1-Mediated H3K4 Methylation in the Regulation of Transcriptional Initiation by RNA Polymerase II , 2009, Molecular and Cellular Biology.

[51]  A. Shilatifard,et al.  Histone H2BK123 monoubiquitination is the critical determinant for H3K4 and H3K79 trimethylation by COMPASS and Dot1 , 2009, The Journal of cell biology.

[52]  G. Crabtree,et al.  MicroRNA-mediated switching of chromatin-remodelling complexes in neural development , 2009, Nature.

[53]  Peter A. Jones,et al.  Selective Anchoring of DNA Methyltransferases 3A and 3B to Nucleosomes Containing Methylated DNA , 2009, Molecular and Cellular Biology.

[54]  J. Rinn,et al.  Many human large intergenic noncoding RNAs associate with chromatin-modifying complexes and affect gene expression , 2009, Proceedings of the National Academy of Sciences.

[55]  Rune R. Frants,et al.  Specific Loss of Histone H3 Lysine 9 Trimethylation and HP1γ/Cohesin Binding at D4Z4 Repeats Is Associated with Facioscapulohumeral Dystrophy (FSHD) , 2009, PLoS genetics.

[56]  C. Bloomfield,et al.  MicroRNA-29b induces global DNA hypomethylation and tumor suppressor gene reexpression in acute myeloid leukemia by targeting directly DNMT3A and 3B and indirectly DNMT1. , 2009, Blood.

[57]  Howard Y. Chang,et al.  Genome-wide views of chromatin structure. , 2009, Annual review of biochemistry.

[58]  B. Cairns,et al.  The biology of chromatin remodeling complexes. , 2009, Annual review of biochemistry.

[59]  E. Heard,et al.  X inactivation and the complexities of silencing a sex chromosome. , 2009, Current opinion in cell biology.

[60]  N. Heintz,et al.  The Nuclear DNA Base 5-Hydroxymethylcytosine Is Present in Purkinje Neurons and the Brain , 2009, Science.

[61]  David R. Liu,et al.  Conversion of 5-Methylcytosine to 5-Hydroxymethylcytosine in Mammalian DNA by MLL Partner TET1 , 2009, Science.

[62]  R. Gay,et al.  Epigenetic control in rheumatoid arthritis synovial fibroblasts , 2009, Nature Reviews Rheumatology.

[63]  Israel Steinfeld,et al.  Developmental programming of CpG island methylation profiles in the human genome , 2009, Nature Structural &Molecular Biology.

[64]  J. Lieberman,et al.  miR-24–mediated downregulation of H2AX suppresses DNA repair in terminally differentiated blood cells , 2009, Nature Structural &Molecular Biology.

[65]  E. Androphy,et al.  The SWI/SNF chromatin remodeling subunit BRG1 is a critical regulator of p53 necessary for proliferation of malignant cells , 2009, Oncogene.

[66]  Andrew J. Bannister,et al.  Phosphorylation of Histone H3 Thr-45 Is Linked to Apoptosis*♦ , 2009, The Journal of Biological Chemistry.

[67]  D. Reisman,et al.  The SWI/SNF complex and cancer , 2009, Oncogene.

[68]  R. Place,et al.  miR-449a targets HDAC-1 and induces growth arrest in prostate cancer , 2009, Oncogene.

[69]  P. Laird,et al.  Locking in on the human methylome , 2009, Nature Biotechnology.

[70]  J. Mattick The Genetic Signatures of Noncoding RNAs , 2009, PLoS genetics.

[71]  S. Jacobsen,et al.  Regulation of DNMT1 stability through SET7-mediated lysine methylation in mammalian cells , 2009, Proceedings of the National Academy of Sciences.

[72]  K. Usdin,et al.  Chromatin Remodeling in the Noncoding Repeat Expansion Diseases* , 2009, Journal of Biological Chemistry.

[73]  Carla Oliveira,et al.  A TARBP2 mutation in human cancer impairs microRNA processing and DICER1 function , 2009, Nature Genetics.

[74]  Robert L Moritz,et al.  PRMT5-mediated methylation of histone H4R3 recruits DNMT3A, coupling histone and DNA methylation in gene silencing , 2009, Nature Structural &Molecular Biology.

[75]  J. Hansen,et al.  Recent advances in MeCP2 structure and function. , 2009, Biochemistry and cell biology = Biochimie et biologie cellulaire.

[76]  P. Visscher,et al.  DNA methylation profiles in monozygotic and dizygotic twins , 2009, Nature Genetics.

[77]  P. Zamore,et al.  Small silencing RNAs: an expanding universe , 2009, Nature Reviews Genetics.

[78]  D. Moazed Small RNAs in transcriptional gene silencing and genome defence , 2009, Nature.

[79]  Bradley E. Bernstein,et al.  Pluripotent Chromatin State , 2009, Science.

[80]  P. Muñoz,et al.  Chromatin dynamics coupled to DNA repair , 2009, Epigenetics.

[81]  Helena Santos-Rosa,et al.  Histone H3 tail clipping regulates gene expression , 2008, Nature Structural &Molecular Biology.

[82]  S. Varambally,et al.  Genomic Loss of microRNA-101 Leads to Overexpression of Histone Methyltransferase EZH2 in Cancer , 2008, Science.

[83]  M. Esteller Epigenetics in evolution and disease , 2008, The Lancet.

[84]  P. Riederer,et al.  Different methylation of the TNF-alpha promoter in cortex and substantia nigra: Implications for selective neuronal vulnerability , 2008, Neurobiology of Disease.

[85]  Andrew Min,et al.  Lymphocytes From Patients With Type 1 Diabetes Display a Distinct Profile of Chromatin Histone H3 Lysine 9 Dimethylation , 2008, Diabetes.

[86]  E. Ballestar,et al.  Epigenetic connections between autoimmune disorders and haematological malignancies. , 2008, Trends in immunology.

[87]  W. Dai,et al.  Phosphorylation of H3S10 Blocks the Access of H3K9 by Specific Antibodies and Histone Methyltransferase , 2008, Journal of Biological Chemistry.

[88]  M. Esteller,et al.  Mecp2-Null Mice Provide New Neuronal Targets for Rett Syndrome , 2008, PloS one.

[89]  S. Henikoff,et al.  Histone H2A.Z and DNA methylation are mutually antagonistic chromatin marks , 2008, Nature.

[90]  Xiaobo Xia,et al.  H3K79 methylation profiles define murine and human MLL-AF4 leukemias. , 2008, Cancer cell.

[91]  H. Kimura,et al.  G9a/GLP complexes independently mediate H3K9 and DNA methylation to silence transcription , 2008, The EMBO journal.

[92]  S. Ropero,et al.  A microRNA DNA methylation signature for human cancer metastasis , 2008, Proceedings of the National Academy of Sciences.

[93]  E. Li,et al.  The Histone H3K79 Methyltransferase Dot1L Is Essential for Mammalian Development and Heterochromatin Structure , 2008, PLoS genetics.

[94]  M. Esteller,et al.  Chromatin remodeling factor CHD5 is silenced by promoter CpG island hypermethylation in human cancer , 2008, Epigenetics.

[95]  Peter A. Jones,et al.  DNA methylation analysis by digital bisulfite genomic sequencing and digital MethyLight , 2008, Nucleic acids research.

[96]  T. Mikkelsen,et al.  Genome-scale DNA methylation maps of pluripotent and differentiated cells , 2008, Nature.

[97]  Michael Q. Zhang,et al.  Combinatorial patterns of histone acetylations and methylations in the human genome , 2008, Nature Genetics.

[98]  R. Durbin,et al.  A Bayesian deconvolution strategy for immunoprecipitation-based DNA methylome analysis , 2008, Nature Biotechnology.

[99]  James D. Brenton,et al.  Somatically acquired hypomethylation of IGF2 in breast and colorectal cancer , 2008, Human molecular genetics.

[100]  Stephen T. C. Wong,et al.  MeCP2, a Key Contributor to Neurological Disease, Activates and Represses Transcription , 2008, Science.

[101]  M. Esteller,et al.  Proteins that bind methylated DNA and human cancer: reading the wrong words , 2008, British Journal of Cancer.

[102]  Tasuku Nomura,et al.  MeCP2-dependent repression of an imprinted miR-184 released by depolarization. , 2008, Human molecular genetics.

[103]  M. Sanchez-Cespedes,et al.  Involvement of the chromatin-remodeling factor BRG1/SMARCA4 in human cancer , 2008, Epigenetics.

[104]  Dustin E. Schones,et al.  Dynamic Regulation of Nucleosome Positioning in the Human Genome , 2008, Cell.

[105]  Qian Tao,et al.  DNA methyltransferase 3B (DNMT3B) mutations in ICF syndrome lead to altered epigenetic modifications and aberrant expression of genes regulating development, neurogenesis and immune function. , 2008, Human molecular genetics.

[106]  D. Trabzuni,et al.  The Friedreich ataxia GAA repeat expansion mutation induces comparable epigenetic changes in human and transgenic mouse brain and heart tissues. , 2007, Human molecular genetics.

[107]  Peter A. Jones,et al.  Role of nucleosomal occupancy in the epigenetic silencing of the MLH1 CpG island. , 2007, Cancer cell.

[108]  S. Gay,et al.  Epigenetics in inflammatory rheumatic diseases. , 2007, Arthritis and rheumatism.

[109]  Hideaki Kato,et al.  Alterations of DNA methylation and histone modifications contribute to gene silencing in hepatocellular carcinomas , 2007, Hepatology research : the official journal of the Japan Society of Hepatology.

[110]  A. Shilatifard,et al.  Covalent modifications of histones during development and disease pathogenesis , 2007, Nature Structural &Molecular Biology.

[111]  Yang Shi,et al.  Histone lysine demethylases: emerging roles in development, physiology and disease , 2007, Nature Reviews Genetics.

[112]  Yingming Zhao,et al.  JMJD6 Is a Histone Arginine Demethylase , 2007, Science.

[113]  N. Sonenberg,et al.  UHRF1 Plays a Role in Maintaining DNA Methylation in Mammalian Cells , 2007, Science.

[114]  D. Reinberg,et al.  NAD+-dependent deacetylation of H4 lysine 16 by class III HDACs , 2007, Oncogene.

[115]  C. Allis,et al.  DNMT3L connects unmethylated lysine 4 of histone H3 to de novo methylation of DNA , 2007, Nature.

[116]  T. Mikkelsen,et al.  Genome-wide maps of chromatin state in pluripotent and lineage-committed cells , 2007, Nature.

[117]  Howard Y. Chang,et al.  Functional Demarcation of Active and Silent Chromatin Domains in Human HOX Loci by Noncoding RNAs , 2007, Cell.

[118]  S. Muller,et al.  Apoptosis-induced acetylation of histones is pathogenic in systemic lupus erythematosus. , 2007, Arthritis and rheumatism.

[119]  M. Esteller Epigenetic gene silencing in cancer: the DNA hypermethylome. , 2007, Human molecular genetics.

[120]  C. Caldas,et al.  Cancer genetics of epigenetic genes. , 2007, Human molecular genetics.

[121]  M. Fraga,et al.  The Polycomb group protein EZH2 directly controls DNA methylation , 2007, Nature.

[122]  M. Esteller Cancer epigenomics: DNA methylomes and histone-modification maps , 2007, Nature Reviews Genetics.

[123]  M. Fraga,et al.  Epigenetic disruption of ribosomal RNA genes and nucleolar architecture in DNA methyltransferase 1 (Dnmt1) deficient cells , 2007, Nucleic acids research.

[124]  Robert A. Martienssen,et al.  Noncoding RNAs and Gene Silencing , 2007, Cell.

[125]  A. Chess,et al.  Gene Body-Specific Methylation on the Active X Chromosome , 2007, Science.

[126]  T. Kouzarides Chromatin Modifications and Their Function , 2007, Cell.

[127]  Bing Li,et al.  The Role of Chromatin during Transcription , 2007, Cell.

[128]  M. Fraga,et al.  Genetic unmasking of an epigenetically silenced microRNA in human cancer cells. , 2007, Cancer research.

[129]  K. Sandhu,et al.  Circular chromosome conformation capture (4C) uncovers extensive networks of epigenetically regulated intra- and interchromosomal interactions , 2006, Nature Genetics.

[130]  G. Haegeman,et al.  Keeping up NF-kappaB appearances: epigenetic control of immunity or inflammation-triggered epigenetics. , 2006, Biochemical pharmacology.

[131]  S. Perlman,et al.  Histone deacetylase inhibitors reverse gene silencing in Friedreich's ataxia , 2006, Nature chemical biology.

[132]  J. Dekker,et al.  The active FMR1 promoter is associated with a large domain of altered chromatin conformation with embedded local histone modifications , 2006, Proceedings of the National Academy of Sciences.

[133]  Thomas A. Milne,et al.  A PHD finger of NURF couples histone H3 lysine 4 trimethylation with chromatin remodelling , 2006, Nature.

[134]  Peter A. Jones,et al.  Specific activation of microRNA-127 with downregulation of the proto-oncogene BCL6 by chromatin-modifying drugs in human cancer cells. , 2006, Cancer cell.

[135]  L. Aaltonen,et al.  A truncating mutation of HDAC2 in human cancers confers resistance to histone deacetylase inhibition , 2006, Nature Genetics.

[136]  Clare Stirzaker,et al.  Epigenetic remodeling in colorectal cancer results in coordinate gene suppression across an entire chromosome band , 2006, Nature Genetics.

[137]  James A. Cuff,et al.  A Bivalent Chromatin Structure Marks Key Developmental Genes in Embryonic Stem Cells , 2006, Cell.

[138]  Xiaoyu Zhang,et al.  Methylation of tRNAAsp by the DNA Methyltransferase Homolog Dnmt2 , 2006, Science.

[139]  Tanja Waldmann,et al.  HP1 Binds Specifically to Lys26-methylated Histone H1.4, whereas Simultaneous Ser27 Phosphorylation Blocks HP1 Binding* , 2005, Journal of Biological Chemistry.

[140]  A. Shilatifard,et al.  Recruitment of MLL by HMG-domain protein iBRAF promotes neural differentiation , 2005, Nature Cell Biology.

[141]  A. Riggs,et al.  Physical and functional interactions between the human DNMT3L protein and members of the de novo methyltransferase family , 2005, Journal of cellular biochemistry.

[142]  K. Robertson DNA methylation and human disease , 2005, Nature Reviews Genetics.

[143]  Wolf Reik,et al.  Co-evolution of X-chromosome inactivation and imprinting in mammals , 2005, Nature Reviews Genetics.

[144]  A. Hartmann,et al.  Elevated nuclear maspin expression is associated with microsatellite instability and high tumour grade in colorectal cancer , 2005, The Journal of pathology.

[145]  M. Fraga,et al.  Loss of acetylation at Lys16 and trimethylation at Lys20 of histone H4 is a common hallmark of human cancer , 2005, Nature Genetics.

[146]  A. El-Osta,et al.  Brahma links the SWI/SNF chromatin-remodeling complex with MeCP2-dependent transcriptional silencing , 2005, Nature Genetics.

[147]  P. Cin,et al.  Uterine Leiomyomata with t(10;17) Disrupt the Histone Acetyltransferase MORF , 2004, Cancer Research.

[148]  Yusuke Nakamura,et al.  SMYD3 encodes a histone methyltransferase involved in the proliferation of cancer cells , 2004, Nature Cell Biology.

[149]  M. Hendrix,et al.  Aberrant methylation of the maspin promoter is an early event in human breast cancer. , 2004, Neoplasia.

[150]  E. Kandel,et al.  Chromatin Acetylation, Memory, and LTP Are Impaired in CBP+/− Mice A Model for the Cognitive Deficit in Rubinstein-Taybi Syndrome and Its Amelioration , 2004, Neuron.

[151]  Ping Zhu,et al.  Induction of HDAC2 expression upon loss of APC in colorectal tumorigenesis. , 2004, Cancer cell.

[152]  Stuart H. Orkin,et al.  The SWI/SNF complex — chromatin and cancer , 2004, Nature Reviews Cancer.

[153]  R. Jaenisch,et al.  Induction of Tumors in Mice by Genomic Hypomethylation , 2003, Science.

[154]  Tony Kouzarides,et al.  The Methyl-CpG-binding Protein MeCP2 Links DNA Methylation to Histone Methylation* , 2003, The Journal of Biological Chemistry.

[155]  Elisabeth Dawson,et al.  Mutation analysis of EP300 in colon, breast and ovarian carcinomas , 2002, International journal of cancer.

[156]  M. Esteller CpG island hypermethylation and tumor suppressor genes: a booming present, a brighter future , 2002, Oncogene.

[157]  Hong Duan,et al.  Role for DNA methylation in the control of cell type–specific maspin expression , 2002, Nature Genetics.

[158]  S. Minucci,et al.  Methyltransferase Recruitment and DNA Hypermethylation of Target Promoters by an Oncogenic Transcription Factor , 2002, Science.

[159]  T. Bestor,et al.  Dnmt3L and the Establishment of Maternal Genomic Imprints , 2001, Science.

[160]  R. Jaenisch,et al.  Nuclear Cloning and Epigenetic Reprogramming of the Genome , 2001, Science.

[161]  G. Kammer,et al.  Trichostatin A reverses skewed expression of CD154, interleukin-10, and interferon-γ gene and protein expression in lupus T cells , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[162]  M. J. Barratt,et al.  Phosphoacetylation of histone H3 on c‐fos‐ and c‐jun‐associated nucleosomes upon gene activation , 2000, The EMBO journal.

[163]  K. Ajiro Histone H2B Phosphorylation in Mammalian Apoptotic Cells , 2000, The Journal of Biological Chemistry.

[164]  H. Ng,et al.  Human DNA-(cytosine-5) methyltransferase-PCNA complex as a target for p21WAF1. , 1997, Science.

[165]  A. Feinberg,et al.  Hypomethylation of DNA from benign and malignant human colon neoplasms. , 1985, Science.

[166]  C. Waddington An Introduction to Modern Genetics , 1939 .

[167]  Peter A. Jones,et al.  Epigenetics in cancer. , 2010, Carcinogenesis.

[168]  E. Li,et al.  The lysine demethylase LSD1 (KDM1) is required for maintenance of global DNA methylation , 2009, Nature Genetics.

[169]  S. Sebert,et al.  Nutritional programming of the metabolic syndrome , 2009, Nature Reviews Endocrinology.

[170]  S. Henikoff,et al.  Genome-wide analysis of Arabidopsis thaliana DNA methylation uncovers an interdependence between methylation and transcription , 2007, Nature Genetics.

[171]  P. Molloy,et al.  DNA hypomethylation and human diseases. , 2007, Biochimica et biophysica acta.

[172]  Jan-Fang Cheng,et al.  Loss of silent-chromatin looping and impaired imprinting of DLX5 in Rett syndrome , 2005, Nature Genetics.

[173]  James A. Birchler,et al.  RNAi-mediated pathways in the nucleus , 2005, Nature Reviews Genetics.

[174]  T. Spector,et al.  From The Cover : Epigenetic differences arise during the lifetime of monozygotic twins , 2005 .

[175]  A. De Sario,et al.  Clinical and molecular overview of inherited disorders resulting from epigenomic dysregulation , 2022 .

[176]  William A. Cunningham,et al.  Personality and Social Psychology Bulletin Self-categorization with a Novel Mixed-race Group Moderates Automatic Social and Racial Biases , 2022 .