Association between thiopurine medication exposure and Alzheimer's disease among a cohort of patients with inflammatory bowel disease
暂无分享,去创建一个
[1] M. Buffelli,et al. Rac1 activation links tau hyperphosphorylation and Aβ dysmetabolism in Alzheimer’s disease , 2018, Acta neuropathologica communications.
[2] Fan Hu,et al. Distinctive roles of Rac1 and Rab29 in LRRK2 mediated membrane trafficking and neurite outgrowth , 2018, Journal of biomedical research.
[3] F. LaFerla,et al. Synaptic Impairment in Alzheimer’s Disease: A Dysregulated Symphony , 2017, Trends in Neurosciences.
[4] C. Mulder,et al. Rac1 as a Potential Pharmacodynamic Biomarker for Thiopurine Therapy in Inflammatory Bowel Disease , 2016, Therapeutic drug monitoring.
[5] D. Nicholson,et al. Evidence for Alzheimer’s disease-linked synapse loss and compensation in mouse and human hippocampal CA1 pyramidal neurons , 2015, Brain Structure and Function.
[6] V. de Waard,et al. 6-Mercaptopurine Reduces Macrophage Activation and Gut Epithelium Proliferation Through Inhibition of GTPase Rac1 , 2014, Inflammatory bowel diseases.
[7] V. de Waard,et al. Inhibition of GTPase Rac1 in Endothelium by 6-Mercaptopurine Results in Immunosuppression in Nonimmune Cells: New Target for an Old Drug , 2014, The Journal of Immunology.
[8] J. Zugaza,et al. 1–42 β-Amyloid peptide requires PDK1/nPKC/Rac 1 pathway to induce neuronal death , 2013, Translational Psychiatry.
[9] B. Hyman,et al. Neuropathological alterations in Alzheimer disease. , 2011, Cold Spring Harbor perspectives in medicine.
[10] Odelia Y. N. Bongmba,et al. Modulation of dendritic spines and synaptic function by Rac1: A possible link to Fragile X syndrome pathology , 2011, Brain Research.
[11] S. Lewin,et al. Pharmacy adherence measures to assess adherence to antiretroviral therapy: review of the literature and implications for treatment monitoring. , 2011, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.
[12] T. Kihara,et al. Rac1 inhibition negatively regulates transcriptional activity of the amyloid precursor protein gene , 2009, Journal of neuroscience research.
[13] M. Moskowitz,et al. Rac1 Is a Critical Mediator of Endothelium-Derived Neurotrophic Activity , 2009, Science Signaling.
[14] S. Hadano,et al. The Rab5 Activator ALS2/alsin Acts as a Novel Rac1 Effector through Rac1-activated Endocytosis* , 2007, Journal of Biological Chemistry.
[15] F. Schmitt,et al. Synaptic alterations in CA1 in mild Alzheimer disease and mild cognitive impairment , 2007, Neurology.
[16] L. Mucke,et al. A network dysfunction perspective on neurodegenerative diseases , 2006, Nature.
[17] M. Neurath,et al. Azathioprine Suppresses Ezrin-Radixin-Moesin-Dependent T Cell-APC Conjugation through Inhibition of Vav Guanosine Exchange Activity on Rac Proteins , 2006, The Journal of Immunology.
[18] R. Maccioni,et al. Modulation of the JNK and p38 pathways by cdk5 protein kinase in a transgenic mouse model of Alzheimer's disease , 2003, Neuroreport.
[19] D. Bennett,et al. Subicular dendritic arborization in Alzheimer's disease correlates with neurofibrillary tangle density. , 2003, The American journal of pathology.
[20] B. Horazdovsky,et al. Biochemical characterization of Alsin, a Rab5 and Rac1 guanine nucleotide exchange factor. , 2005, Methods in enzymology.