Bone remodeling theory applied to the study of n unit-elements model.

The aim of this paper is to illustrate the application of mathematical tools for the analysis of non-linear dynamical systems to the study of global stability of one kind of bone remodeling scheme applied to n unit-elements model. The particular aspects analyzed here are the stationary states related to this theory and a condition of their stability. The non-linear equations governing the remodeling process are solved by finite-difference method and the well-known results on the heterogeneous spatial organizations have been retrieved and confirm the analytical study. This kind of remodeling theory is useful for investigating the effects of physiological parameters on the development, maintenance, and adaptation of bone under mechanical loading.

[1]  D P Fyhrie,et al.  Trabecular bone density and loading history: regulation of connective tissue biology by mechanical energy. , 1987, Journal of biomechanics.

[2]  Gilbert Strang,et al.  Introduction to applied mathematics , 1988 .

[3]  H. Grootenboer,et al.  The behavior of adaptive bone-remodeling simulation models. , 1992, Journal of biomechanics.

[4]  William L. Ditto,et al.  Removal, Suppression, and Control of Chaos by Nonlinear Design , 1995 .

[5]  M Viceconti,et al.  Global asymptotic stability of bone remodeling theories: a new approach based on non-linear dynamical systems analysis. , 1997, Journal of biomechanics.

[6]  J. Currey The effect of porosity and mineral content on the Young's modulus of elasticity of compact bone. , 1988, Journal of biomechanics.

[7]  S. Cowin,et al.  Candidates for the mechanosensory system in bone. , 1991, Journal of biomechanical engineering.

[8]  L. Taber Biomechanics of Growth, Remodeling, and Morphogenesis , 1995 .

[9]  J J Hamilton,et al.  An analytical and numerical study of the stability of bone remodelling theories: dependence on microstructural stimulus. , 1992, Journal of biomechanics.

[10]  S. Cowin,et al.  Bone remodeling I: theory of adaptive elasticity , 1976 .

[11]  H Weinans,et al.  A physiological approach to the simulation of bone remodeling as a self-organizational control process. , 1994, Journal of biomechanics.

[12]  D P Fyhrie,et al.  The adaptation of bone apparent density to applied load. , 1995, Journal of biomechanics.

[13]  S C Cowin,et al.  Bone stress adaptation models. , 1993, Journal of biomechanical engineering.

[14]  Mustapha Zidi Contribution à la modélisation du remodelage de Pos trabéculaire , 1998 .