A Novel CDC42 Variant with Impaired Thymopoiesis, IL-7R Signaling, PAK1 Binding, and TCR Repertoire Diversity.

[1]  J. Casanova,et al.  HPV-Related Skin Phenotypes in Patients with Inborn Errors of Immunity , 2022, Pathogens.

[2]  M. Tartaglia,et al.  Mutations at the C-terminus of CDC42 cause distinct hematopoietic and autoinflammatory disorders. , 2022, The Journal of allergy and clinical immunology.

[3]  Christopher C. Griffith,et al.  Functional HPV-specific PD-1+ stem-like CD8 T cells in head and neck cancer , 2021, Nature.

[4]  D. Hougaard,et al.  Implementation of SCID Screening in Denmark , 2021, International journal of neonatal screening.

[5]  L. Notarangelo,et al.  Poor T-cell receptor β repertoire diversity early posttransplant for severe combined immunodeficiency predicts failure of immune reconstitution , 2021, The Journal of allergy and clinical immunology.

[6]  C. Giaquinto,et al.  Plasticity of the Immune System in Children Following Treatment Interruption in HIV-1 Infection , 2021, Frontiers in Immunology.

[7]  J. Delon,et al.  RHO GTPases: from new partners to complex immune syndromes , 2021, Nature Reviews Immunology.

[8]  J. Dudakov,et al.  Dynamics of thymus function and T cell receptor repertoire breadth in health and disease , 2021, Seminars in immunopathology.

[9]  R. Mendoza-Londono,et al.  Progressive decline of T and B cell numbers and function in a patient with CDC42 deficiency , 2021, Immunologic Research.

[10]  T. Mogensen,et al.  STK4 Deficiency Impairs Innate Immunity and Interferon Production Through Negative Regulation of TBK1-IRF3 Signaling , 2020, Journal of Clinical Immunology.

[11]  Y. Lau,et al.  Establishing Simultaneous T Cell Receptor Excision Circles (TREC) and K-Deleting Recombination Excision Circles (KREC) Quantification Assays and Laboratory Reference Intervals in Healthy Individuals of Different Age Groups in Hong Kong , 2020, Frontiers in Immunology.

[12]  R. Płoski,et al.  A Novel CDC42 Mutation in an 11-Year Old Child Manifesting as Syndromic Immunodeficiency, Autoinflammation, Hemophagocytic Lymphohistiocytosis, and Malignancy: A Case Report , 2020, Frontiers in Immunology.

[13]  Stephanie Dallaire,et al.  Development of a Multiplex Real-Time PCR Assay for the Newborn Screening of SCID, SMA, and XLA , 2019, International journal of neonatal screening.

[14]  P. Palma,et al.  Novel Compound Heterozygous Mutations in IL-7 Receptor α Gene in a 15-Month-Old Girl Presenting With Thrombocytopenia, Normal T Cell Count and Maternal Engraftment , 2019, Front. Immunol..

[15]  Ivan K. Chinn,et al.  A novel disorder involving dyshematopoiesis, inflammation, and HLH due to aberrant CDC42 function , 2019, The Journal of experimental medicine.

[16]  Peter Schmid,et al.  Spatial heterogeneity of the T cell receptor repertoire reflects the mutational landscape in lung cancer , 2019, Nature Medicine.

[17]  J. Bartram,et al.  Clinical benefit of a high‐throughput sequencing approach for minimal residual disease in acute lymphoblastic leukemia , 2019, Pediatric blood & cancer.

[18]  K. Young,et al.  Epstein-Barr Virus-Positive Natural Killer/T-Cell Lymphoma , 2019, Front. Oncol..

[19]  Jun Jiang,et al.  TCR Repertoire as a Novel Indicator for Immune Monitoring and Prognosis Assessment of Patients With Cervical Cancer , 2018, Frontiers in immunology.

[20]  R. Callard,et al.  Clinical T Cell Receptor Repertoire Deep Sequencing and Analysis: An Application to Monitor Immune Reconstitution Following Cord Blood Transplantation , 2018, Front. Immunol..

[21]  Douglas P. Larsen,et al.  Functional Dysregulation of CDC42 Causes Diverse Developmental Phenotypes. , 2018, American journal of human genetics.

[22]  P. Bradley,et al.  Quantifiable predictive features define epitope-specific T cell receptor repertoires , 2017, Nature.

[23]  Alessandro Sette,et al.  Identifying specificity groups in the T cell receptor repertoire , 2017, Nature.

[24]  Mikaël Salson,et al.  Vidjil: A Web Platform for Analysis of High-Throughput Repertoire Sequencing , 2016, PloS one.

[25]  H. Grimes,et al.  Coordination of IL-7 receptor and T-cell receptor signaling by cell-division cycle 42 in T-cell homeostasis , 2010, Proceedings of the National Academy of Sciences.

[26]  M. Bentahir,et al.  Rho GTPase Cdc42 is essential for human T-cell development , 2010, Haematologica.

[27]  M. Mescher,et al.  Antigen Controls IL-7Rα Expression Levels on CD8 T Cells during Full Activation or Tolerance Induction1 , 2008, The Journal of Immunology.

[28]  A. Singer,et al.  IL-7 Receptor Signals Inhibit Expression of Transcription Factors TCF-1, LEF-1, and RORγt , 2004, The Journal of experimental medicine.

[29]  E. Wherry,et al.  Selective expression of the interleukin 7 receptor identifies effector CD8 T cells that give rise to long-lived memory cells , 2003, Nature Immunology.

[30]  J. Sprent,et al.  Interleukin (IL)-15 and IL-7 Jointly Regulate Homeostatic Proliferation of Memory Phenotype CD8+ Cells but Are Not Required for Memory Phenotype CD4+ Cells , 2002, The Journal of experimental medicine.

[31]  T. Moore,et al.  Inhibition of gamma delta T cell development and early thymocyte maturation in IL-7 -/- mice. , 1996, Journal of immunology.