Hybrid-state free precession in nuclear magnetic resonance

The dynamics of large spin-1/2 ensembles are commonly described by the Bloch equation, which is characterized by the magnetization’s non-linear response to the driving magnetic field. Consequently, most magnetic field variations result in non-intuitive spin dynamics, which are sensitive to small calibration errors. Although simplistic field variations result in robust spin dynamics, they do not explore the richness of the system’s phase space. Here, we identify adiabaticity conditions that span a large experiment design space with tractable dynamics. All dynamics are trapped in a one-dimensional subspace, namely in the magnetization’s absolute value, which is in a transient state, while its direction adiabatically follows the steady state. In this hybrid state, the polar angle is the effective drive of the spin dynamics. As an example, we optimize this drive for robust and efficient quantification of spin relaxation times and utilize it for magnetic resonance imaging of the human brain.Nuclear magnetic resonance is a technique ubiquitous in a diverse range of scientific and clinical fields. However, it can be sensitive to small deviations in the driving magnetic fields, which can easily disrupt measurement accuracy. Here, the authors develop a hybrid-state free precession approach which demonstrates greater robustness against deviations in the magnetic fields and exhibits an improved signal-to-noise ratio.