Mitogen-activated Protein Kinase Kinase 2 Activation Is Essential for Progression through the G2/M Checkpoint Arrest in Cells Exposed to Ionizing Radiation*
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[1] J. Kato,et al. Silencing factors participate in DNA repair and recombination in Saccharomyces cerevisiae , 1997, Nature.
[2] Yuko Yamaguchi-Iwai,et al. Reduced X-Ray Resistance and Homologous Recombination Frequencies in a RAD54−/− Mutant of the Chicken DT40 Cell Line , 1997, Cell.
[3] M. Lovett,et al. A single ataxia telangiectasia gene with a product similar to PI-3 kinase. , 1995, Science.
[4] R. Davis,et al. The role of c-Jun N-terminal kinase (JNK) in apoptosis induced by ultraviolet C and gamma radiation. Duration of JNK activation may determine cell death and proliferation. , 1996, The Journal of biological chemistry.
[5] D. Beach,et al. Reversible tyrosine phosphorylation of cdc2: Dephosphorylation accompanies activation during entry into mitosis , 1989, Cell.
[6] D. Riches,et al. Tumor necrosis factor alpha rapidly activates the mitogen-activated protein kinase (MAPK) cascade in a MAPK kinase kinase-dependent, c-Raf-1-independent fashion in mouse macrophages. , 1995, Proceedings of the National Academy of Sciences of the United States of America.
[7] M. Karin,et al. Mitogen-activated protein kinase cascades and regulation of gene expression. , 1996, Current opinion in immunology.
[8] A. Ashworth,et al. Tumorigenesis and a DNA repair defect in mice with a truncating Brca2 mutation , 1997, Nature Genetics.
[9] C. Marshall,et al. Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells , 1994, Cell.
[10] D. Hallahan,et al. Protein kinase C mediates x-ray inducibility of nuclear signal transducers EGR1 and JUN. , 1991, Proceedings of the National Academy of Sciences of the United States of America.
[11] R. Weichselbaum,et al. Defective induction of stress-activated protein kinase activity in ataxia-telangiectasia cells exposed to ionizing radiation. , 1995, Cancer research.
[12] R. Weichselbaum,et al. Role for c-Abl tyrosine kinase in growth arrest response to DNA damage , 1996, Nature.
[13] R. Fleischmann,et al. DNA-PKcs: a T-cell tumour suppressor encoded at the mouse scid locus , 1997, Nature Genetics.
[14] D. Hallahan,et al. c-jun and Egr-1 Participate in DNA Synthesis and Cell Survival in Response to Ionizing Radiation Exposure (*) , 1995, The Journal of Biological Chemistry.
[15] G. V. Vande Woude,et al. Synergy between the Mos/mitogen-activated protein kinase pathway and loss of p53 function in transformation and chromosome instability , 1997, Molecular and cellular biology.
[16] Y. Shiloh,et al. Interaction between ATM protein and c-Abl in response to DNA damage , 1997, Nature.
[17] E. Nishida,et al. Activation mechanism and function of the MAP kinase cascade , 1995, Molecular reproduction and development.
[18] R. Jaussi,et al. Effects of ionizing radiation and caffeine treatment on cyclin dependent kinase complexes in V79 hamster cells. , 1994, Cellular signalling.
[19] N. Ahn,et al. Mitogen-activated protein kinase activation is not necessary for, but antagonizes, 3T3-L1 adipocytic differentiation , 1997, Molecular and cellular biology.
[20] D. Morgan,et al. Role of inhibitory CDC2 phosphorylation in radiation-induced G2 arrest in human cells , 1996, The Journal of cell biology.
[21] R. Muschel,et al. Potential molecular targets for manipulating the radiation response. , 1997, International journal of radiation oncology, biology, physics.
[22] N. Ahn,et al. Megakaryocytic differentiation induced by constitutive activation of mitogen-activated protein kinase kinase , 1997, Molecular and cellular biology.
[23] E. Krebs,et al. The MAPK signaling cascade , 1995, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[24] G. Eichele,et al. Embryonic lethality and radiation hypersensitivity mediated by Rad51 in mice lacking Brca2 , 1997, Nature.
[25] K. Guan,et al. Three genes of the MAP kinase cascade, mek-2, mpk-1/sur-1 and let-60 ras, are required for meiotic cell cycle progression in Caenorhabditis elegans. , 1995, Development.
[26] L. Zon,et al. Activation of stress-activated protein kinase by MEKK1 phosphorylation of its activator SEK1 , 1994, Nature.
[27] B. Halliwell,et al. Oxygen free radicals and iron in relation to biology and medicine: some problems and concepts. , 1986, Archives of biochemistry and biophysics.
[28] Marty W. Mayo,et al. TNF- and Cancer Therapy-Induced Apoptosis: Potentiation by Inhibition of NF-κB , 1996, Science.
[29] P. Dent,et al. Association of Grb2 with Sos and Ras with Raf-1 upon gamma irradiation of breast cancer cells , 1997, Oncogene.
[30] K. Pumiglia,et al. Cell cycle arrest mediated by the MEK/mitogen-activated protein kinase pathway. , 1997, Proceedings of the National Academy of Sciences of the United States of America.
[31] K. Guan,et al. The mitogen activated protein kinase signal transduction pathway: from the cell surface to the nucleus. , 1994, Cellular signalling.
[32] P. Dent,et al. Identification and characterization of a new mammalian mitogen-activated protein kinase kinase, MKK2 , 1993, Molecular and cellular biology.
[33] C. N. Coleman,et al. X-irradiation, phorbol esters, and H2O2 stimulate mitogen-activated protein kinase activity in NIH-3T3 cells through the formation of reactive oxygen intermediates. , 1994, Cancer research.
[34] M. Sklar. The ras oncogenes increase the intrinsic resistance of NIH 3T3 cells to ionizing radiation. , 1988, Science.
[35] D. Hallahan,et al. Ionizing radiation regulates expression of the c-jun protooncogene. , 1990, Proceedings of the National Academy of Sciences of the United States of America.
[36] J. Woodgett,et al. Mammalian Mitogen-activated Protein Kinase Pathways Are Regulated through Formation of Specific Kinase-Activator Complexes* , 1996, The Journal of Biological Chemistry.
[37] B. Halliwell,et al. Oxygen toxicity, oxygen radicals, transition metals and disease. , 1984, The Biochemical journal.
[38] M. Cobb,et al. MAP kinase becomes stably activated at metaphase and is associated with microtubule-organizing centers during meiotic maturation of mouse oocytes. , 1993, Developmental biology.
[39] D. W. Abbott,et al. Double-strand break repair deficiency and radiation sensitivity in BRCA2 mutant cancer cells. , 1998, Journal of the National Cancer Institute.
[40] C. Crews,et al. Extracellular signals and reversible protein phosphorylation: What to Mek of it all , 1993, Cell.
[41] Philip R. Cohen,et al. PD 098059 Is a Specific Inhibitor of the Activation of Mitogen-activated Protein Kinase Kinase in Vitro and in Vivo(*) , 1995, The Journal of Biological Chemistry.
[42] G L Johnson,et al. Differential activation of ERK and JNK mitogen-activated protein kinases by Raf-1 and MEKK. , 1994, Science.
[43] N. Ahn,et al. Transformation of mammalian cells by constitutively active MAP kinase kinase. , 1994, Science.
[44] S. Inoue,et al. Functional interaction between DNA-PK and c-Abl in response to DNA damage , 1997, Nature.
[45] D. Baltimore,et al. Ataxia telangiectasia mutant protein activates c-Abl tyrosine kinase in response to ionizing radiation , 1997, Nature.
[46] Francis Collins,et al. Atm-Deficient Mice: A Paradigm of Ataxia Telangiectasia , 1996, Cell.
[47] A. Sharrocks,et al. Integration of MAP kinase signal transduction pathways at the serum response element. , 1995, Science.
[48] M. Brenneman,et al. Repair of site-specific double-strand breaks in a mammalian chromosome by homologous and illegitimate recombination , 1997, Molecular and cellular biology.
[49] M. Dorée,et al. MAPK inactivation is required for the G2 to M‐phase transition of the first mitotic cell cycle , 1997, The EMBO journal.
[50] R. Weichselbaum,et al. Activation of the pp90rsk and mitogen-activated serine/threonine protein kinases by ionizing radiation. , 1994, Proceedings of the National Academy of Sciences of the United States of America.
[51] A. Ashworth,et al. Identification of the sites in MAP kinase kinase‐1 phosphorylated by p74raf‐1. , 1994, The EMBO journal.
[52] R. Muschel,et al. Effects of ionizing radiation on cell cycle progression , 1995, Radiation and environmental biophysics.
[53] Roeder Gs. Meiotic chromosomes: it takes two to tango , 1997 .
[54] A. Bridges,et al. A synthetic inhibitor of the mitogen-activated protein kinase cascade. , 1995, Proceedings of the National Academy of Sciences of the United States of America.
[55] Jiahuai Han,et al. Independent human MAP-kinase signal transduction pathways defined by MEK and MKK isoforms , 1995, Science.
[56] J. Avruch,et al. Sounding the Alarm: Protein Kinase Cascades Activated by Stress and Inflammation* , 1996, The Journal of Biological Chemistry.
[57] M. Connelly,et al. DNA-dependent protein kinase catalytic subunit: A relative of phosphatidylinositol 3-kinase and the ataxia telangiectasia gene product , 1995, Cell.
[58] K. Guan,et al. Cloning and characterization of two distinct human extracellular signal-regulated kinase activator kinases, MEK1 and MEK2. , 1993, The Journal of biological chemistry.
[59] A. Picard,et al. Mitogen-activated protein kinase activation down-regulates a mechanism that inactivates cyclin B-cdc2 kinase in G2-arrested oocytes. , 1997, Molecular biology of the cell.
[60] S. Jackson,et al. DNA damage detection by DNA dependent protein kinase and related enzymes. , 1996, Cancer surveys.
[61] N. Ahn,et al. Constitutively active mitogen-activated protein kinase kinase 1 (MAPKK1) and MAPKK2 mediate similar transcriptional and morphological responses. , 1996, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.
[62] M. Lieber,et al. Interaction of DNA‐dependent protein kinase with DNA and with Ku: biochemical and atomic‐force microscopy studies , 1997, The EMBO journal.
[63] D. Hallahan,et al. Radiation signaling mediated by Jun activation following dissociation from a cell type-specific repressor. , 1993, The Journal of biological chemistry.
[64] B. Ponder,et al. Involvement of Brca2 in DNA repair. , 1998, Molecular cell.
[65] D. Hallahan,et al. Ionizing radiation activates transcription of the EGR1 gene via CArG elements. , 1992, Proceedings of the National Academy of Sciences of the United States of America.
[66] T. Whiteside,et al. Activation of Raf by ionizing radiation , 1996, Nature.
[67] B. Ponder,et al. Thymic lymphomas in mice with a truncating mutation in Brca2. , 1998, Cancer research.
[68] E. Krebs,et al. Overexpression of mitogen-activated protein kinase kinase (MAPKK) and its mutants in NIH 3T3 cells. Evidence that MAPKK involvement in cellular proliferation is regulated by phosphorylation of serine residues in its kinase subdomains VII and VIII. , 1994, The Journal of biological chemistry.
[69] D. W. Abbott,et al. Finkel-Biskis-Reilly Mouse Osteosarcoma Virus v-fosInhibits the Cellular Response to Ionizing Radiation in a Myristoylation-dependent Manner* , 1997, The Journal of Biological Chemistry.
[70] Derek W. Abbott,et al. Finkel-Biskis-Reilly Osteosarcoma Virus v-Fos Inhibits Adipogenesis and Both the Activity and Expression of CCAAT/Enhancer Binding Protein α, a Key Regulator of Adipocyte Differentiation* , 1997, The Journal of Biological Chemistry.
[71] A. Ashworth,et al. Assay and expression of mitogen-activated protein kinase, MAP kinase kinase, and Raf. , 1995, Methods in enzymology.