radiological quantification in rheumatoid arthritis for enhancing the efficacy and accelerating The "X-Ray RheumaCoach" software: a novel tool

Ann Rheum Dis2003;62:579–582Background: Precise diagnosis and follow up treatment ofrheumatoid arthritis (RA) requires objective quantification,which is still lacking. For this purpose, radiological analy-ses are considered to be the most appropriate method.Objective: To develop computer assisted quantificationsoftware that is particularly applicable to joint scoring inrheumatic disorders.Methods: 3914 radiographs from hands and feet of 190patients with RA were collected, expertly examined,analysed, and statistically evaluated. Radiographs werequantified using the conventional Larsen score and the“X-Ray RheumaCoach” (XRRC) software. The XRRC is aJava stand alone application which can support andaccelerate, but not fully automate, the scoring procedure inRA. The scorer can apply both the Larsen and theRatingen-Rau scores.Results: Compared with conventional scoring procedures,the XRRC software accelerated quantification time by∼25%. The program, which is now available on the inter-net free of charge, ran stably and proved to be a consist-ently valuable tool.Conclusions: Compared with conventional scoring meth-ods, the XRRC software offers several advantages: (a)structured data analysis and input that minimises varianceby standardisation; (b) faster and more precise calculationof sum scores and indices; (c) permanent data storing andfast access to the software’s database; (d) the possibility ofcross calculation to other scores; (e) “user friendly”technology and a dedicated help program; (f) fast accessand data transfer through the internet if desired; and (g)reliable documentation of results in a specially designedprintout.