β-Cell Secretory Products Activate α-Cell ATP-Dependent Potassium Channels to Inhibit Glucagon Release
暂无分享,去创建一个
[1] Xiaosong Ma,et al. ATP-Sensitive K+ Channel–Dependent Regulation of Glucagon Release and Electrical Activity by Glucose in Wild-Type and SUR1−/− Mouse α-Cells , 2004 .
[2] R. Dérand,et al. Zinc is both an intracellular and extracellular regulator of KATP channel function , 2004, The Journal of physiology.
[3] P. Rorsman,et al. Glucose inhibition of glucagon secretion from rat alpha-cells is mediated by GABA released from neighboring beta-cells. , 2004, Diabetes.
[4] S. Theander,et al. Glucose sensitivity and metabolism-secretion coupling studied during two-year continuous culture in INS-1E insulinoma cells. , 2004, Endocrinology.
[5] T. Kigoshi,et al. Receptor gene expression of glucagon-like peptide-1, but not glucose-dependent insulinotropic polypeptide, in rat nodose ganglion cells , 2004, Autonomic Neuroscience.
[6] E. Samols,et al. In situ binding of islet hormones in the isolated perfused rat pancreas: evidence for local high concentrations of islet hormones via the islet-acinar axis , 1995, Diabetologia.
[7] R. Unger,et al. Glucagon physiology and pathophysiology in the light of new advances , 1985, Diabetologia.
[8] P. Rorsman,et al. Glucose Inhibition of Glucagon Secretion From Rat-Cells Is Mediated by GABA Released From Neighboring-Cells , 2004 .
[9] D. Coy,et al. Intra-islet somatostatin regulates glucagon release via type 2 somatostatin receptors in rats. , 2003, Diabetes.
[10] Bei B. Zhang,et al. Glucagon and regulation of glucose metabolism. , 2003, American journal of physiology. Endocrinology and metabolism.
[11] C. Wollheim,et al. Islet β-cell secretion determines glucagon release from neighbouring α-cells , 2003, Nature Cell Biology.
[12] R. Pederson,et al. Effect of glucagon-like peptide 1 (7-36 amide) on insulin-mediated glucose uptake in patients with type 1 diabetes. , 2003, Diabetes care.
[13] J. Holst. Implementation of GLP-1 based therapy of type 2 diabetes mellitus using DPP-IV inhibitors. , 2003, Advances in experimental medicine and biology.
[14] J. Kere,et al. Physical exercise-induced hyperinsulinemic hypoglycemia is an autosomal-dominant trait characterized by abnormal pyruvate-induced insulin release. , 2003, Diabetes.
[15] D. D’Alessio,et al. Impaired beta-cell function, incretin effect, and glucagon suppression in patients with type 1 diabetes who have normal fasting glucose. , 2002, Diabetes.
[16] P. Cryer,et al. Intraislet hyperinsulinemia prevents the glucagon response to hypoglycemia despite an intact autonomic response. , 2002, Diabetes.
[17] W. Qian,et al. Detection and imaging of zinc secretion from pancreatic beta-cells using a new fluorescent zinc indicator. , 2002, Journal of the American Chemical Society.
[18] J. Walsh,et al. Immunoneutralization of Somatostatin, Insulin, and Glucagon Causes Alterations in Islet Cell Secretion in the Isolated Perfused Human Pancreas , 2001, Pancreas.
[19] L. Satin,et al. Insulin activates ATP-sensitive K(+) channels in pancreatic beta-cells through a phosphatidylinositol 3-kinase-dependent pathway. , 2001, Diabetes.
[20] R. Burcelin,et al. Evidence that extrapancreatic GLUT2-dependent glucose sensors control glucagon secretion. , 2001, Diabetes.
[21] Jochen Roeper,et al. ATP-sensitive K+ channels in the hypothalamus are essential for the maintenance of glucose homeostasis , 2001, Nature Neuroscience.
[22] M. Stoltenberg,et al. Autometallography allows ultrastructural monitoring of zinc in the endocrine pancreas , 2001, Histochemistry and Cell Biology.
[23] Y. Dunant,et al. Zinc‐induced changes in ionic currents of clonal rat pancreatic β‐cells: activation of ATP‐sensitive K+ channels , 2000, The Journal of physiology.
[24] V. Routh,et al. Insulin activates ATP-sensitive K+ channels in hypothalamic neurons of lean, but not obese rats , 2000, Nature Neuroscience.
[25] C. Wollheim,et al. Mitochondrial glutamate acts as a messenger in glucose-induced insulin exocytosis , 1999, Nature.
[26] P. Rorsman,et al. Characterisation of sulphonylurea and ATP-regulated K+ channels in rat pancreatic A-cells , 1999, Pflügers Archiv.
[27] R. Rizza,et al. Impact of lack of suppression of glucagon on glucose tolerance in humans , 1999 .
[28] D Brown,et al. Onset of Bursting in Oxytocin Cells in Suckled Rats , 1997, The Journal of physiology.
[29] P. Rorsman,et al. Adrenaline Stimulates Glucagon Secretion in Pancreatic A-Cells by Increasing the Ca2+ Current and the Number of Granules Close to the L-Type Ca2+ Channels , 1997, The Journal of general physiology.
[30] M. Prentki,et al. Metabolic Fate of Glucose in Purified Islet Cells , 1997, The Journal of Biological Chemistry.
[31] P. Rorsman,et al. Glucagon-Like Peptide I and Glucose-Dependent Insulinotropic Polypeptide Stimulate Ca2+-Induced Secretion in Rat α-Cells by a Protein Kinase A–Mediated Mechanism , 1997, Diabetes.
[32] P. Smith,et al. Electrogenic arginine transport mediates stimulus‐secretion coupling in mouse pancreatic beta‐cells. , 1997, The Journal of physiology.
[33] O. Madsen,et al. The glucose sensor protein glucokinase is expressed in glucagon-producing alpha-cells. , 1996, Proceedings of the National Academy of Sciences of the United States of America.
[34] D. Pipeleers,et al. Expression and Functional Activity of Glucagon, Glucagon-Like Peptide I, and Glucose-Dependent Insulinotropic Peptide Receptors in Rat Pancreatic Islet Cells , 1996, Diabetes.
[35] D. Pipeleers,et al. Differences in Glucose Transporter Gene Expression between Rat Pancreatic α- and β-Cells Are Correlated to Differences in Glucose Transport but Not in Glucose Utilization (*) , 1995, The Journal of Biological Chemistry.
[36] M. J. MacDonald,et al. Low lactate dehydrogenase and high mitochondrial glycerol phosphate dehydrogenase in pancreatic beta-cells. Potential role in nutrient sensing. , 1994, The Journal of biological chemistry.
[37] M. Namba,et al. Glucagonostatic and Insulinotropic Action of Glucagonlike Peptide I-(7–36)-Amide , 1989, Diabetes.
[38] S. Ohashi,et al. Comparison of the effects of glucagon-like peptide-1-(1-37) and -(7-37) and glucagon on islet hormone release from isolated perfused canine and rat pancreases. , 1989, Endocrinology.
[39] V. Marks,et al. The order of islet microvascular cellular perfusion is B----A----D in the perfused rat pancreas. , 1988, The Journal of clinical investigation.
[40] P. Rorsman,et al. Inhibition of ATP-regulated K+ channels precedes depolarization-induced increase in cytoplasmic free Ca2+ concentration in pancreatic beta-cells. , 1987, The Journal of biological chemistry.
[41] E. Samols,et al. Retrograde perfusion as a model for testing the relative effects of glucose versus insulin on the A cell. , 1986, The Journal of clinical investigation.
[42] D. Pipeleers,et al. A new in vitro model for the study of pancreatic A and B cells. , 1985, Endocrinology.
[43] E. Hooghe-Peters,et al. Interplay of nutrients and hormones in the regulation of insulin release. , 1985, Endocrinology.
[44] D. Pipeleers,et al. Interplay of nutrients and hormones in the regulation of glucagon release. , 1985, Endocrinology.
[45] L. Orci,et al. Insulin within islets is a physiologic glucagon release inhibitor. , 1984, The Journal of clinical investigation.
[46] G. Grodsky,et al. Relationship Between Insulin Release and 65Zinc Efflux from Rat Pancreatic Islets Maintained in Tissue Culture , 1984, Diabetes.
[47] H. Taniguchi,et al. Modulation of somatostatin release by endogenous glucagon and insulin: physiological relationship between A, B and D cells in rat pancreatic islets. , 1982, Endocrinologia japonica.
[48] M. Lorenzi,et al. Stimulatory effects of tolbutamide infusion on plasma glucagon in insulin-dependent diabetic subjects. , 1982, The Journal of clinical endocrinology and metabolism.
[49] P. Lacy,et al. Zinc-Induced Inhibition of Insulin Secretion from Isolated Rat Islets of Langerhans , 1981, Diabetes.
[50] G. Grodsky,et al. Pancreatic action of the sulfonylureas. , 1977, Federation proceedings.
[51] G. Weir,et al. Glucagon Secretion from the Perfused Pancreas of Streptozotocin-treated Rats , 1976, Diabetes.
[52] R. Unger,et al. The effect of insulin on the alpha-cell response to hyperglycemia in long-standing alloxan diabetes. , 1974, The Journal of clinical investigation.