Targeted degradation of CD147 proteins in melanoma.
暂无分享,去创建一个
Zhe Zhou | Qianbin Li | Gaoyun Hu | Xiang Chen | Y. Wang | Ling Tang | C. Peng | Xu Zhang | Shuo Hu | Zhuo Chen | Jing Long | Yayun Li | Qi Chang
[1] Philip P. Chamberlain,et al. Development of targeted protein degradation therapeutics , 2019, Nature Chemical Biology.
[2] M. Mori,et al. Signal Transducer and Activator of Transcription Protein 3 (STAT3): an Update on its Direct Inhibitors as Promising Anticancer Agents. , 2019, Current medicinal chemistry.
[3] Bin Yang,et al. Proteolysis targeting chimeras (PROTACs) in 'beyond rule-of-five' chemical space: Recent progress and future challenges. , 2019, Bioorganic & medicinal chemistry letters.
[4] A. Vaisi-Raygani,et al. CD147 as an apoptosis regulator in spermatogenesis: deciphering its association with matrix metalloproteinases’ pathway , 2019, Molecular Biology Reports.
[5] David M. Wilson,et al. Development of a Novel B-Cell Lymphoma 6 (BCL6) PROTAC To Provide Insight into Small Molecule Targeting of BCL6. , 2018, ACS chemical biology.
[6] Xiaowei Xu,et al. Downregulation of CD147 induces malignant melanoma cell apoptosis via the regulation of IGFBP2 expression , 2018, International journal of oncology.
[7] Liwu Fu,et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs , 2018, EBioMedicine.
[8] Carola Berking,et al. Melanoma , 2018, The Lancet.
[9] Jing Wang,et al. The Advantages of Targeted Protein Degradation Over Inhibition: An RTK Case Study. , 2017, Cell chemical biology.
[10] Youli Xiao,et al. Chemical proteomics reveal CD147 as a functional target of pseudolaric acid B in human cancer cells. , 2017, Chemical communications.
[11] Xiang Chen,et al. Targeting CD147 is a Novel Strategy for Antitumor Therapy. , 2017, Current pharmaceutical design.
[12] C. Crews,et al. Targeted protein degradation by PROTACs☆ , 2017, Pharmacology & therapeutics.
[13] C. Crews,et al. Waste disposal—An attractive strategy for cancer therapy , 2017, Science.
[14] M. Naito,et al. In Vivo Knockdown of Pathogenic Proteins via Specific and Nongenetic Inhibitor of Apoptosis Protein (IAP)-dependent Protein Erasers (SNIPERs)* , 2017, The Journal of Biological Chemistry.
[15] B. Bastian,et al. From melanocytes to melanomas , 2016, Nature Reviews Cancer.
[16] V. Holubekova,et al. Determination of malignant potential of cervical intraepithelial neoplasia , 2016, Tumor Biology.
[17] Eunhwa Ko,et al. Modular PROTAC Design for the Degradation of Oncogenic BCR-ABL. , 2016, Angewandte Chemie.
[18] T. Muramatsu. Basigin (CD147), a multifunctional transmembrane glycoprotein with various binding partners , 2015, Journal of biochemistry.
[19] C. Crews,et al. Hijacking the E3 Ubiquitin Ligase Cereblon to Efficiently Target BRD4. , 2015, Chemistry & biology.
[20] X. Chen,et al. CD147 interacts with NDUFS6 in regulating mitochondrial complex I activity and the mitochondrial apoptotic pathway in human malignant melanoma cells. , 2014, Current molecular medicine.
[21] Bin Wang,et al. A chimeric antibody targeting CD147 inhibits hepatocellular carcinoma cell motility via FAK-PI3K-Akt-Girdin signaling pathway , 2014, Clinical & Experimental Metastasis.
[22] Yang Zhang,et al. A regulatory loop involving miR-22, Sp1, and c-Myc modulates CD147 expression in breast cancer invasion and metastasis. , 2014, Cancer research.
[23] T. Lawrence,et al. HAb18G/CD147 Promotes pSTAT3-Mediated Pancreatic Cancer Development via CD44s , 2013, Clinical Cancer Research.
[24] Wen-bin Tang,et al. A novel interaction between calcium-modulating cyclophilin ligand and Basigin regulates calcium signaling and matrix metalloproteinase activities in human melanoma cells. , 2013, Cancer letters.
[25] H. Xie,et al. Propranolol induces apoptosis of human umbilical vein endothelial cells through downregulation of CD147 , 2012, The British journal of dermatology.
[26] S. Qiu,et al. Interaction of pseudolaric acid B with the colchicine site of tubulin. , 2012, Biochemical pharmacology.
[27] Hannes Stockinger,et al. Cancer-related issues of CD147. , 2010, Cancer genomics & proteomics.
[28] T. Kanekura,et al. CD147/basigin promotes progression of malignant melanoma and other cancers. , 2010, Journal of dermatological science.
[29] Xiang Chen,et al. A CD147-targeting siRNA inhibits the proliferation, invasiveness, and VEGF production of human malignant melanoma cells by down-regulating glycolysis. , 2009, Cancer letters.
[30] Jing Lin,et al. A small interfering CD147-targeting RNA inhibited the proliferation, invasiveness, and metastatic activity of malignant melanoma. , 2006, Cancer research.
[31] Jian Ding,et al. Pseudolarix Acid B, a New Tubulin-Binding Agent, Inhibits Angiogenesis by Interacting with a Novel Binding Site on Tubulin , 2006, Molecular Pharmacology.
[32] L. Chow,et al. Pseudolaric Acid B, a Novel Microtubule-Destabilizing Agent That Circumvents Multidrug Resistance Phenotype and Exhibits Antitumor Activity In vivo , 2005, Clinical Cancer Research.
[33] Yi Tang,et al. Extracellular matrix metalloproteinase inducer stimulates tumor angiogenesis by elevating vascular endothelial cell growth factor and matrix metalloproteinases. , 2005, Cancer research.
[34] T. Hoang‐Xuan,et al. EMMPRIN/CD147, an MMP modulator in cancer, development and tissue repair. , 2005, Biochimie.
[35] T. Kanekura,et al. Basigin (cd147) is expressed on melanoma cells and induces tumor cell invasion by stimulating production of matrix metalloproteinases by fibroblasts , 2002, International journal of cancer.
[36] Z. Werb,et al. New functions for the matrix metalloproteinases in cancer progression , 2002, Nature Reviews Cancer.
[37] I. Stamenkovic. Matrix metalloproteinases in tumor invasion and metastasis. , 2000, Seminars in cancer biology.
[38] Y. Okada,et al. Glioma cell extracellular matrix metalloproteinase inducer (EMMPRIN) (CD147) stimulates production of membrane-type matrix metalloproteinases and activated gelatinase A in co-cultures with brain-derived fibroblasts. , 2000, Cancer letters.
[39] J. Regezi,et al. Expression of EMMPRIN by oral squamous cell carcinoma , 2000 .
[40] M. Polette,et al. Expression of the Extracellular Matrix Metalloproteinase Inducer (EMMPRIN) and the Matrix Metalloproteinase-2 in Bronchopulmonary and Breast Lesions , 1999, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.