Multiresolution localization and segmentation of the optical disc in fundus images using inpainted background and vessel information

In this paper we present a novel method for the automatic location and segmentation of the optical disk in fundus images. It is based on the decoupling of vessel and background information obtained with morphological segmentation and inpainting. A multiresolution optimization scheme finding elliptic contours optimally adapted to a brightness model is then applied on the inpainted brightness image, under the constraint that a reasonable amount of vasculature must be present inside the disc. An effective objective function and a multiresolution scheme allow a deterministic optimizer to converge on the OD contour with good accuracy, while the vessel-based constraint limits wrong contour detections in anomalous cases. Our initial experiments (30 DRIVE images, ground truth from two doctors) suggest that the method can provide accurate results both in term of optic disc location and contour segmentation accuracy.

[1]  J. Thiran,et al.  Identification of the optic disk boundary in retinal images using active contours , 1999 .

[2]  Xiaodong Wu,et al.  Segmentation of the optic nerve head combining pixel classification and graph search , 2007, SPIE Medical Imaging.

[3]  Asoke K. Nandi,et al.  Automated localisation of retinal optic disk using Hough transform , 2008, 2008 5th IEEE International Symposium on Biomedical Imaging: From Nano to Macro.

[4]  Juan Xu,et al.  Automated Optic Disk Boundary Detection by Modified Active Contour Model , 2007, IEEE Transactions on Biomedical Engineering.

[5]  Max A. Viergever,et al.  Ridge-based vessel segmentation in color images of the retina , 2004, IEEE Transactions on Medical Imaging.

[6]  Alin Achim,et al.  18th IEEE International Conference on Image Processing, ICIP 2011, Brussels, Belgium, September 11-14, 2011 , 2011, ICIP.

[7]  Aliaa A. A. Youssif,et al.  Optic Disc Detection From Normalized Digital Fundus Images by Means of a Vessels' Direction Matched Filter , 2008, IEEE Transactions on Medical Imaging.

[8]  Rangaraj M. Rangayyan,et al.  Detection of the Optic Nerve Head in Fundus Images of the Retina with Gabor Filters and Phase Portrait Analysis , 2010, Journal of Digital Imaging.

[9]  Guillermo Sapiro,et al.  Image inpainting , 2000, SIGGRAPH.

[10]  Bram van Ginneken,et al.  Fast detection of the optic disc and fovea in color fundus photographs , 2009, Medical Image Anal..

[11]  Emanuele Trucco,et al.  Robust optic disc location via combination of weak detectors , 2008, 2008 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society.

[12]  Patrick Pérez,et al.  Object removal by exemplar-based inpainting , 2003, 2003 IEEE Computer Society Conference on Computer Vision and Pattern Recognition, 2003. Proceedings..