HIV-1 protease specificity of peptide cleavage is sufficient for processing of gag and pol polyproteins.

[1]  L. Skeggs,et al.  KINETICS OF THE REACTION OF RENIN WITH NINE SYNTHETIC PEPTIDE SUBSTRATES , 1968, The Journal of experimental medicine.

[2]  J. Powers,et al.  Subsite specificity of porcine pepsin. , 1977, Advances in experimental medicine and biology.

[3]  L. Hood,et al.  Direct microsequence analysis of polypeptides using an improved sequenator, a nonprotein carrier (polybrene), and high pressure liquid chromatography. , 1978, Biochemistry.

[4]  R. Eisenman,et al.  In vitro cleavage of avian retrovirus gag proteins by viral protease p15. , 1979, Virology.

[5]  R. Sauer,et al.  Amino acid sequence of p15 from avian myeloblastosis virus complex. , 1981, Biochemistry.

[6]  S. Goff,et al.  A deletion mutation in the 5' part of the pol gene of Moloney murine leukemia virus blocks proteolytic processing of the gag and pol polyproteins , 1985, Journal of virology.

[7]  T. Copeland,et al.  Characterization of gp41 as the transmembrane protein coded by the HTLV-III/LAV envelope gene. , 1985, Science.

[8]  Olivier Danos,et al.  Nucleotide sequence of the AIDS virus, LAV , 1985, Cell.

[9]  Mark L. Pearson,et al.  Complete nucleotide sequence of the AIDS virus, HTLV-III , 1985, Nature.

[10]  K. Steimer,et al.  Nucleotide sequence and expression of an AIDS-associated retrovirus (ARV-2). , 1985, Science.

[11]  I. Katoh,et al.  Bovine leukemia virus protease: purification, chemical analysis, and in vitro processing of gag precursor polyproteins , 1986, Journal of virology.

[12]  J. Coligan,et al.  Structural characterization of reverse transcriptase and endonuclease polypeptides of the acquired immunodeficiency syndrome retrovirus , 1986, Journal of virology.

[13]  William R. Taylor,et al.  A structural model for the retroviral proteases , 1987, Nature.

[14]  M. Emerman,et al.  Genome organization and transactivation of the human immunodeficiency virus type 2 , 1987, Nature.

[15]  W R Taylor,et al.  Sequence specificity of retroviral proteases. , 1987, Nature.

[16]  T. Yasunaga,et al.  Inhibition of retroviral protease activity by an aspartyl proteinase inhibitor , 1987, Nature.

[17]  T. Copeland,et al.  Immunological and chemical analysis of P6, the carboxyl-terminal fragment of HIV P15. , 1987, AIDS research and human retroviruses.