Extrapyramidal inhibition of the urinary bladder.

Abstract Inhibition of spontaneous (‘reflex’, ‘micturition’) contractions of the urinary bladder by electrical stimulation of anterior brain stem structures functionally related to the extrapyramidal system has been described. Areas in and around the nucleus ruber, the substantia nigra and adjacent tegmental fields and the subthalamus were found to be even more effective in this respect than the pallidum and the anterior and central portions of the nucleus ventralis lateralis of the thalamus. The possible relationship of this inhibitory system to the finding of bladder dysfunction in patients with extrapyramidal disease is suggested.

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