Quercetin exerts cardiovascular protective effects in LPS-induced dysfunction in vivo by regulating inflammatory cytokine expression, NF-κB phosphorylation, and caspase activity

[1]  R. Hotchkiss,et al.  Persistent Lymphopenia After Diagnosis of Sepsis Predicts Mortality , 2014, Shock.

[2]  M. Schetinger,et al.  Neuroprotective role of quercetin in locomotor activities and cholinergic neurotransmission in rats experimentally demyelinated with ethidium bromide. , 2014, Life sciences.

[3]  Xuebin Qu,et al.  Quercetin improves hypoxia-ischemia induced cognitive deficits via promoting remyelination in neonatal rat , 2014, Brain Research.

[4]  S. Deem,et al.  Characterization of Cardiac Dysfunction in Sepsis: An Ongoing Challenge , 2014, Shock.

[5]  G. Vitalpur.  Innate Immune Function and Mortality in Critically Ill Children With Influenza: A Multicenter Study , 2013, Pediatrics.

[6]  C. Sprung,et al.  Surviving Sepsis Campaign: International Guidelines for Management of Severe Sepsis and Septic Shock 2012 , 2013, Critical care medicine.

[7]  Hong Ma,et al.  Sufentanil postconditioning protects the myocardium from ischemia-reperfusion via PI3K/Akt-GSK-3β pathway. , 2012, The Journal of surgical research.

[8]  R. Hotchkiss,et al.  Immunosuppression in Patients Who Die of Sepsis and Multiple Organ Failure , 2012 .

[9]  Ying Song,et al.  Protective roles of quercetin in acute myocardial ischemia and reperfusion injury in rats , 2012, Molecular Biology Reports.

[10]  Dashi Qi,et al.  Quercetin Attenuates Cell Apoptosis in Focal Cerebral Ischemia Rat Brain Via Activation of BDNF–TrkB–PI3K/Akt Signaling Pathway , 2012, Neurochemical Research.

[11]  A. Breier,et al.  Acute treatment with polyphenol quercetin improves postischemic recovery of isolated perfused rat hearts after global ischemia. , 2010, Canadian journal of physiology and pharmacology.

[12]  Xiaohong Wang,et al.  Overexpression of Hsp20 prevents endotoxin-induced myocardial dysfunction and apoptosis via inhibition of NF-kappaB activation. , 2009, Journal of molecular and cellular cardiology.

[13]  N. Groce,et al.  Surviving sepsis in low-income and middle-income countries: new directions for care and research. , 2009, The Lancet. Infectious diseases.

[14]  G. Wang,et al.  Effects of quercetin on gene and protein expression of NOX and NOS after myocardial ischemia and reperfusion in rabbit. , 2009, Cardiovascular therapeutics.

[15]  P. Kolattukudy,et al.  Protection against lipopolysaccharide-induced myocardial dysfunction in mice by cardiac-specific expression of soluble Fas. , 2007, Journal of molecular and cellular cardiology.

[16]  M. Singer,et al.  Mechanisms of sepsis-induced cardiac dysfunction , 2007, Critical care medicine.

[17]  Dong-Mei Wu,et al.  Quercetin reverses d-galactose induced neurotoxicity in mouse brain , 2006, Behavioural Brain Research.

[18]  R. Favory,et al.  Ventricular Myocyte Caspases Are Directly Responsible for Endotoxin-Induced Cardiac Dysfunction , 2005, Circulation.

[19]  Brown Ma,et al.  NF-kappaB action in sepsis: the innate immune system and the heart. , 2004 .

[20]  Mitchell M. Levy,et al.  Surviving Sepsis Campaign guidelines for management of severe sepsis and septic shock , 2004, Critical care medicine.

[21]  J. Chiche,et al.  Brain natriuretic peptide: A marker of myocardial dysfunction and prognosis during severe sepsis , 2004, Critical care medicine.

[22]  I. Iglesias,et al.  Quercetin, a flavonoid antioxidant, prevents and protects against ethanol-induced oxidative stress in mouse liver. , 2003, Biological & pharmaceutical bulletin.

[23]  J. Parrillo,et al.  Myocardial dysfunction in septic shock: Part II. Role of cytokines and nitric oxide. , 2001, Journal of cardiothoracic and vascular anesthesia.

[24]  G. Clermont,et al.  Epidemiology of severe sepsis in the United States: Analysis of incidence, outcome, and associated costs of care , 2001, Critical care medicine.

[25]  D. Mann,et al.  In vivo expression of proinflammatory mediators in the adult heart after endotoxin administration: the role of toll-like receptor-4. , 2001, The Journal of infectious diseases.

[26]  J. Hogg,et al.  Myocardial morphometric changes related to decreased contractility after endotoxin. , 1996, The American journal of physiology.

[27]  Anand Kumar,et al.  Tumor necrosis factor alpha and interleukin 1beta are responsible for in vitro myocardial cell depression induced by human septic shock serum , 1996, The Journal of experimental medicine.

[28]  T. Scholz,et al.  Myocardial energy metabolism and morphology in a canine model of sepsis. , 1994, The American journal of physiology.

[29]  R. Bone,et al.  Plasma Cytokine and Endotoxin Levels Correlate with Survival in Patients with the Sepsis Syndrome , 1993, Annals of Internal Medicine.

[30]  F. Ognibene,et al.  Septic shock in humans. Advances in the understanding of pathogenesis, cardiovascular dysfunction, and therapy. , 1990, Annals of internal medicine.

[31]  W. Sibbald,et al.  Histologic and ultrastructural changes in nonpulmonary organs during early hyperdynamic sepsis. , 1990, Surgery.

[32]  W. Buurman,et al.  Plasma tumor necrosis factor and mortality in critically ill septic patients. , 1989, Critical care medicine.

[33]  L. Greenfield,et al.  Pathophysiologic responses of the subhuman primate in experimental septic shock. , 1975, Laboratory investigation; a journal of technical methods and pathology.

[34]  Tao YangBin,et al.  Anti-apoptotic and Anti-oxidative Roles of Quercetin After Traumatic Brain Injury , 2014 .

[35]  R. Fudin,et al.  Loss of microvascular negative charges accompanied by interstitial edema in septic rats' heart. , 1992, Circulatory shock.