Blocking NMDA receptor signaling does not decrease hormonal counterregulation to hypoglycemia in humans

[1]  Chris G. Parsons,et al.  Memantine: a NMDA receptor antagonist that improves memory by restoration of homeostasis in the glutamatergic system - too little activation is bad, too much is even worse , 2007, Neuropharmacology.

[2]  B. Pleger,et al.  The NMDA antagonist memantine affects training induced motor cortex plasticity – a study using transcranial magnetic stimulation [ISRCTN65784760] , 2005, BMC Neuroscience.

[3]  S. Lipton The molecular basis of memantine action in Alzheimer's disease and other neurologic disorders: low-affinity, uncompetitive antagonism. , 2005, Current Alzheimer research.

[4]  G. Makara,et al.  Glutamate agonists activate the hypothalamic–pituitary–adrenal axis through hypothalamic paraventricular nucleus but not through vasopressinerg neurons , 2005, Brain Research.

[5]  J. Woods,et al.  Self-administration of fentanyl, cocaine and ketamine: effects on the pituitary–adrenal axis in rhesus monkeys , 2004, Psychopharmacology.

[6]  A. Peters,et al.  The selfish brain: competition for energy resources , 2004, Neuroscience & Biobehavioral Reviews.

[7]  S. Amiel,et al.  Counterregulation to hypoglycaemia: physiology. , 2004, Annales d'endocrinologie.

[8]  H. Suh,et al.  Route-dependent effects of the non-NMDA receptor antagonist CNQX on plasma corticosterone levels in mice , 2003, Progress in Neuro-Psychopharmacology and Biological Psychiatry.

[9]  H. Dinse,et al.  Pharmacological Modulation of Perceptual Learning and Associated Cortical Reorganization , 2003, Science.

[10]  M. Bradbury,et al.  Metabotropic glutamate receptor 5 antagonist-induced stimulation of hypothalamic–pituitary–adrenal axis activity: interaction with serotonergic systems , 2003, Neuropharmacology.

[11]  N. Abumrad,et al.  Contribution of excitatory amino acids to hypoglycemic counter-regulation , 2001, Brain Research.

[12]  V. Yuferov,et al.  Effects of memantine alone and with acute 'binge' cocaine on hypothalamic-pituitary-adrenal activity in the rat. , 1998, European journal of pharmacology.

[13]  B. Ahrén,et al.  Autonomic mediation of glucagon secretion during hypoglycemia: implications for impaired alpha-cell responses in type 1 diabetes. , 1998, Diabetes.

[14]  D. Jezova,et al.  Effect of central administration of the non-NMDA receptor antagonist DNQX on ACTH and corticosterone release before and during immobilization stress. , 1997, Methods and findings in experimental and clinical pharmacology.

[15]  I. Daum,et al.  The NMDA antagonist memantine impairs classical eyeblink conditioning in humans , 1997, Neuroscience Letters.

[16]  D. Jezova,et al.  Endogenous excitatory amino acids are involved in stress-induced adrenocorticotropin and catecholamine release. , 1995, Neuroendocrinology.

[17]  J. Kornhuber,et al.  Cerebrospinal fluid and serum concentrations of the N-methyl-d-aspartate (NMDA) receptor antagonist memantine in man , 1995, Neuroscience Letters.

[18]  R. Porter,et al.  Regional Variations in the Pharmacology of NMDA Receptor Channel Blockers: Implications for Therapeutic Potential , 1995, Journal of neurochemistry.

[19]  J. Krystal,et al.  Subanesthetic effects of the noncompetitive NMDA antagonist, ketamine, in humans. Psychotomimetic, perceptual, cognitive, and neuroendocrine responses. , 1994, Archives of general psychiatry.

[20]  J. N. Hayward,et al.  Glutamate receptors in the rat hypothalamus and pituitary. , 1994, Endocrinology.

[21]  N. Abumrad,et al.  Differential control of glucoregulatory hormone response and glucose metabolism by NMDA and kainate , 1994, Brain Research.

[22]  P. Cryer,et al.  Induction of Hypoglycemia Unawareness by Asymptomatic Nocturnal Hypoglycemia , 1993, Diabetes.

[23]  I. Deary,et al.  Partitioning the symptoms of hypoglycaemia using multi-sample confirmatory factor analysis , 1993, Diabetologia.

[24]  J. Bockaert,et al.  Glutamate stimulates glucagon secretion via an excitatory amino acid receptor of the AMPA subtype in rat pancreas. , 1993, European journal of pharmacology.

[25]  D. Cox,et al.  Perceived Symptoms in the Recognition of Hypoglycemia , 1993, Diabetes Care.

[26]  G. Hempelmann,et al.  [Studies using S-(+)-ketamine on probands. Endocrine and circulatory reactions, recovery and dream experiences]. , 1992, Der Anaesthesist.

[27]  T. Rao,et al.  N-methyl-D-aspartate treatment increases circulating adrenocorticotropin and luteinizing hormone in the rat. , 1991, Endocrinology.

[28]  M. Ferin,et al.  Unexpected inhibitory action of N-methyl-D,L-aspartate or luteinizing hormone release in adult ovariectomized rhesus monkeys: a role of the hypothalamic-adrenal axis. , 1990, Endocrinology.

[29]  P. Wood,et al.  Sigma receptors modulate the hypothalamic-pituitary-adrenal (HPA) axis centrally: evidence for a functional interaction with NMDA receptors, in vivo , 1990, Neuropharmacology.

[30]  T. Plant,et al.  N-methyl-D,L-aspartate elicits hypothalamic gonadotropin-releasing hormone release in prepubertal male rhesus monkeys (Macaca mulatta). , 1987, Endocrinology.

[31]  S. Butcher,et al.  Extracellular Overflow of Neuroactive Amino Acids During Severe Insulin‐Induced Hypoglycemia: In Vivo Dialysis of the Rat Hippocampus , 1986, Journal of neurochemistry.

[32]  J. Robinson,et al.  Influence of handling and sedation on plasma cortisol in rhesus monkeys (Macaca mulatta). , 1976, The Journal of endocrinology.

[33]  C. Shackleton,et al.  Studies on plasma corticosteroids in the rhesus monkey (Macaca mulatta). , 1975, The Journal of endocrinology.

[34]  M. Riepe,et al.  Memantine in Moderate-to-severe Alzheimer's Disease , 2006 .

[35]  D. Brann Glutamate: a major excitatory transmitter in neuroendocrine regulation. , 1995, Neuroendocrinology.

[36]  S. Nakanishi,et al.  MOLECULAR DIVERSITY OF THE GLUTAMATE RECEPTORS , 1992, Clinical neuropharmacology.

[37]  J. Gerich,et al.  Hypoglycemia unawareness. , 1991, Endocrine reviews.

[38]  M. Dallman,et al.  Paraventricular stimulation with glutamate elicits bradycardia and pituitary responses. , 1989, The American journal of physiology.