Identification of Selected in vitro-Generated Phase-I Metabolites of the Steroidal Selective Androgen Receptor Modulator MK-0773 for Doping Control Purposes
暂无分享,去创建一个
M. Thevis | W. Schänzer | U. Karst | O. Krug | A. Thomas | Tina Wigger | Dirk Kuehne | Andreas Lagojda
[1] P. Jadhav,et al. 2-Chloro-4-[[(1R,2R)-2-hydroxy-2-methyl-cyclopentyl]amino]-3-methyl-benzonitrile: A Transdermal Selective Androgen Receptor Modulator (SARM) for Muscle Atrophy. , 2016, Journal of medicinal chemistry.
[2] B. Lee,et al. Comparative safety evaluation of selective androgen receptor modulators and anabolic androgenic steroids , 2015, Expert opinion on drug safety.
[3] M. Thevis,et al. Characterization of a non-approved selective androgen receptor modulator drug candidate sold via the Internet and identification of in vitro generated phase-I metabolites for human sports drug testing. , 2015, Rapid communications in mass spectrometry : RCM.
[4] T. Hitaka,et al. Synthesis and biological evaluation of novel selective androgen receptor modulators (SARMs). Part I. , 2015, Bioorganic & medicinal chemistry.
[5] M. Thevis,et al. In vitro Metabolism Studies on the Selective Androgen Receptor Modulator LG121071 and its Implementation into Human Doping Controls Using Liquid Chromatography-Mass Spectrometry , 2015, European journal of mass spectrometry.
[6] D. Powell,et al. 1-(2-Hydroxy-2-methyl-3-phenoxypropanoyl)indoline-4-carbonitrile derivatives as potent and tissue selective androgen receptor modulators. , 2014, Journal of medicinal chemistry.
[7] A. Dobs,et al. Enobosarm (GTx-024, S-22): a potential treatment for cachexia. , 2014, Future oncology.
[8] Frederick C W Wu,et al. Androgen effects on skeletal muscle: implications for the development and management of frailty , 2014, Asian journal of andrology.
[9] D. Papanicolaou,et al. A phase IIA randomized, placebo-controlled clinical trial to study the efficacy and safety of the selective androgen receptor modulator (SARM), MK-0773 in female participants with sarcopenia , 2013, The journal of nutrition, health & aging.
[10] Z. Sui,et al. Deciphering the selective androgen receptor modulators paradigm , 2013, Expert opinion on drug discovery.
[11] D. Herndon,et al. Burns: an update on current pharmacotherapy , 2012, Expert opinion on pharmacotherapy.
[12] T. Prangé,et al. Discovery of diarylhydantoins as new selective androgen receptor modulators. , 2012, Journal of medicinal chemistry.
[13] N. Triballeau,et al. Identification of a 4-(hydroxymethyl)diarylhydantoin as a selective androgen receptor modulator. , 2012, Journal of medicinal chemistry.
[14] F. Martin,et al. Hormone replacement therapy and physical function in healthy older men. Time to talk hormones? , 2012, Endocrine reviews.
[15] U. Karst,et al. Simulation of the oxidative metabolism of diclofenac by electrochemistry/(liquid chromatography/)mass spectrometry , 2012, Analytical and Bioanalytical Chemistry.
[16] M. Thevis,et al. Investigation of the in vitro metabolism of the emerging drug candidate S107 for doping-preventive purposes. , 2011, Journal of mass spectrometry : JMS.
[17] U. Karst,et al. Online electrochemistry/mass spectrometry in drug metabolism studies: principles and applications , 2010, Expert opinion on drug metabolism & toxicology.
[18] P. Hodor,et al. Discovery of the Selective Androgen Receptor Modulator MK-0773 Using a Rational Development Strategy Based on Differential Transcriptional Requirements for Androgenic Anabolism Versus Reproductive Physiology* , 2010, The Journal of Biological Chemistry.
[19] Ramesh Narayanan,et al. Nonsteroidal selective androgen receptor modulators (SARMs): dissociating the anabolic and androgenic activities of the androgen receptor for therapeutic benefit. , 2009, Journal of medicinal chemistry.
[20] U. Karst,et al. Metabolic studies of tetrazepam based on electrochemical simulation in comparison to in vivo and in vitro methods. , 2009, Journal of chromatography. A.
[21] M. Thevis,et al. Mass spectrometric identification and characterization of a new long-term metabolite of metandienone in human urine. , 2006, Rapid communications in mass spectrometry : RCM.
[22] Chowdhury,et al. Liquid chromatography/mass spectrometry methods for distinguishing N-oxides from hydroxylated compounds , 2000, Analytical chemistry.
[23] Duane D. Miller,et al. Discovery of nonsteroidal androgens. , 1998, Biochemical and biophysical research communications.
[24] A. Q. Maisel. The hormone quest , 1965 .