Overexpressing TGF-β1 in mesenchymal stem cells attenuates organ dysfunction during CLP-induced septic mice by reducing macrophage-driven inflammation

[1]  Shenmin Zhang,et al.  MSC-secreted TGF-β regulates lipopolysaccharide-stimulated macrophage M2-like polarization via the Akt/FoxO1 pathway , 2019, Stem Cell Research & Therapy.

[2]  T. Velkov,et al.  Chloroquine ameliorates carbon tetrachloride-induced acute liver injury in mice via the concomitant inhibition of inflammation and induction of apoptosis , 2018, Cell Death & Disease.

[3]  Yadan Li,et al.  Mesenchymal stem cells attenuate sepsis-induced liver injury via inhibiting M1 polarization of Kupffer cells , 2018, Molecular and Cellular Biochemistry.

[4]  D. Dwivedi,et al.  Body temperature and mouse scoring systems as surrogate markers of death in cecal ligation and puncture sepsis , 2018, Intensive Care Medicine Experimental.

[5]  J. Chao,et al.  circRNA Mediates Silica-Induced Macrophage Activation Via HECTD1/ZC3H12A-Dependent Ubiquitination , 2018, Theranostics.

[6]  E. K. Cunningham,et al.  Mesenchymal Stromal Cells Modulate Macrophages in Clinically Relevant Lung Injury Models by Extracellular Vesicle Mitochondrial Transfer , 2017, American journal of respiratory and critical care medicine.

[7]  Khiany Mathias,et al.  Dimethyl Fumarate Modulates Oxidative Stress and Inflammation in Organs After Sepsis in Rats , 2017, Inflammation.

[8]  N. Matsuda,et al.  Recent advances in the pathophysiology and molecular basis of sepsis‐associated organ dysfunction: Novel therapeutic implications and challenges , 2017, Pharmacology & therapeutics.

[9]  C. Nito,et al.  Mesenchymal Stem Cells Overexpressing Interleukin-10 Promote Neuroprotection in Experimental Acute Ischemic Stroke , 2017, Molecular therapy. Methods & clinical development.

[10]  N. Shapiro,et al.  Number of organ dysfunctions predicts mortality in emergency department patients with suspected infection: a multicenter validation study , 2017, European journal of emergency medicine : official journal of the European Society for Emergency Medicine.

[11]  Zekai Halici,et al.  Sepsis and Septic Shock: Current Treatment Strategies and New Approaches. , 2017, The Eurasian journal of medicine.

[12]  M. Matthay,et al.  Mesenchymal Stem (Stromal) Cells: Biology and Preclinical Evidence for Therapeutic Potential for Organ Dysfunction following Trauma or Sepsis , 2016 .

[13]  H. Qiu,et al.  E-Prostanoid 2 Receptor Overexpression Promotes Mesenchymal Stem Cell Attenuated Lung Injury. , 2016, Human gene therapy.

[14]  Kyung-Ah Cho,et al.  Mesenchymal Stem Cells Modulate the Functional Properties of Microglia via TGF‐β Secretion , 2016, Stem cells translational medicine.

[15]  M. Matthay,et al.  Mitochondrial Transfer via Tunneling Nanotubes is an Important Mechanism by Which Mesenchymal Stem Cells Enhance Macrophage Phagocytosis in the In Vitro and In Vivo Models of ARDS , 2016, Stem cells.

[16]  T. van der Poll.  Future of sepsis therapies , 2016, Critical Care.

[17]  R. Bellomo,et al.  The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3). , 2016, JAMA.

[18]  Yi Yang,et al.  Mesenchymal Stem Cells Overexpressing Angiotensin-Converting Enzyme 2 Rescue Lipopolysaccharide-Induced Lung Injury , 2015, Cell transplantation.

[19]  S. Radakovic,et al.  Cytokine profile in severe gram-positive and gram-negative abdominal sepsis , 2015, Scientific Reports.

[20]  N. Zhang,et al.  CXCR4 Receptor Overexpression in Mesenchymal Stem Cells Facilitates Treatment of Acute Lung Injury in Rats* , 2014, The Journal of Biological Chemistry.

[21]  S. Goerdt,et al.  Macrophage activation and polarization: nomenclature and experimental guidelines. , 2014, Immunity.

[22]  Yong-ming Yao,et al.  Macrophage Polarization in Inflammatory Diseases , 2014, International journal of biological sciences.

[23]  Y. Shu,et al.  Proper Heat Shock Pretreatment Reduces Acute Liver Injury Induced by Carbon Tetrachloride and Accelerates Liver Repair in Mice , 2013, Journal of toxicologic pathology.

[24]  D. McKay,et al.  Bone marrow-derived alternatively activated macrophages reduce colitis without promoting fibrosis: participation of IL-10. , 2013, American journal of physiology. Gastrointestinal and liver physiology.

[25]  N. Heisterkamp,et al.  TGFβ signaling plays a critical role in promoting alternative macrophage activation , 2012, BMC Immunology.

[26]  Armand Keating,et al.  Mesenchymal stromal cells: new directions. , 2012, Cell stem cell.

[27]  Arthur S Slutsky,et al.  Mesenchymal stem cells reduce inflammation while enhancing bacterial clearance and improving survival in sepsis. , 2010, American journal of respiratory and critical care medicine.

[28]  E. Giamarellos‐Bourboulis,et al.  Clarithromycin is an effective immunomodulator in experimental pyelonephritis caused by pan-resistant Klebsiella pneumoniae. , 2006, The Journal of antimicrobial chemotherapy.

[29]  E. Bissonnette,et al.  Adoptive transfer of alveolar macrophages abrogates bronchial hyperresponsiveness. , 2004, American journal of respiratory cell and molecular biology.

[30]  R. Bone,et al.  Immunologic Dissonance: A Continuing Evolution in Our Understanding of the Systemic Inflammatory Response Syndrome (SIRS) and the Multiple Organ Dysfunction Syndrome (MODS) , 1996, Annals of Internal Medicine.

[31]  R. Bone,et al.  Gram-negative sepsis. Background, clinical features, and intervention. , 1991, Chest.

[32]  H. Xia,et al.  microRNA-155 attenuates profibrotic effects of transforming growth factor-beta on human lung fibroblasts. , 2019, Journal of biological regulators and homeostatic agents.

[33]  Changqing Zhu,et al.  Interleukin-10-Overexpressing Mesenchymal Stromal Cells Induce a Series of Regulatory Effects in the Inflammatory System and Promote the Survival of Endotoxin-Induced Acute Lung Injury in Mice Model. , 2018, DNA and cell biology.

[34]  M. Pittenger,et al.  Unraveling the Mesenchymal Stromal Cells' Paracrine Immunomodulatory Effects. , 2016, Transfusion medicine reviews.

[35]  Krisztián Németh,et al.  Bone marrow stromal cells attenuate sepsis via prostaglandin E2–dependent reprogramming of host macrophages to increase their interleukin-10 production , 2009, Nature Medicine.

[36]  S. Gordon.  Alternative activation of macrophages , 2003, Nature Reviews Immunology.

[37]  Hilde van der Togt,et al.  Publisher's Note , 2003, J. Netw. Comput. Appl..

[38]  A. Ellrodt,et al.  Sepsis and septic shock. , 1986, Emergency medicine clinics of North America.