Robust vessel detection and segmentation in ultrasound images by a data-driven approach

This paper presents a learning based vessel detection and segmentation method in real-patient ultrasound (US) liver images. We aim at detecting multiple shaped vessels robustly and automatically, including vessels with weak and ambiguous boundaries. Firstly, vessel candidate regions are detected by a data-driven approach. Multi-channel vessel enhancement maps with complement performances are generated and aggregated under a Conditional Random Field (CRF) framework. Vessel candidates are obtained by thresholding the saliency map. Secondly, regional features are extracted and the probability of each region being a vessel is modeled by random forest regression. Finally, a fast levelset method is developed to refine vessel boundaries. Experiments have been carried out on an US liver dataset with 98 patients. The dataset contains both normal and abnormal liver images. The proposed method in this paper is compared with a traditional Hessian based method, and the average precision is promoted by 56 percents and 7.8 percents for vessel detection and classification, respectively. This improvement shows that our method is more robust to noise, therefore has a better performance than the Hessian based method for the detection of vessels with weak and ambiguous boundaries.

[1]  C. Stewart Retinal Vessel Extraction Using Multiscale Matched Filters, Confidence and Edge Me , 2006 .

[2]  Jiri Matas,et al.  Robust wide-baseline stereo from maximally stable extremal regions , 2004, Image Vis. Comput..

[3]  Noboru Niki,et al.  3D imaging of blood vessels using X-ray rotational angiographic system , 1993, 1993 IEEE Conference Record Nuclear Science Symposium and Medical Imaging Conference.

[4]  Mona Kathryn Garvin,et al.  Automated Segmentation of 3-D Spectral OCT Retinal Blood Vessels by Neural Canal Opening False Positive Suppression , 2010, MICCAI.

[5]  Anil K. Jain,et al.  Fingerprint Image Enhancement: Algorithm and Performance Evaluation , 1998, IEEE Trans. Pattern Anal. Mach. Intell..

[6]  Aliaa A. A. Youssif,et al.  Optic Disc Detection From Normalized Digital Fundus Images by Means of a Vessels' Direction Matched Filter , 2008, IEEE Transactions on Medical Imaging.

[7]  Francis K. H. Quek,et al.  A review of vessel extraction techniques and algorithms , 2004, CSUR.

[8]  Mona Kathryn Garvin,et al.  Automated multimodality concurrent classification for segmenting vessels in 3D spectral OCT and color fundus images , 2011, Medical Imaging.

[9]  Yuzhen Niu,et al.  Saliency Aggregation: A Data-Driven Approach , 2013, 2013 IEEE Conference on Computer Vision and Pattern Recognition.

[10]  Evangelos Dermatas,et al.  Multi-scale retinal vessel segmentation using line tracking , 2010, Comput. Medical Imaging Graph..

[11]  Tony F. Chan,et al.  Active contours without edges , 2001, IEEE Trans. Image Process..

[12]  Matti Pietikäinen,et al.  A comparative study of texture measures with classification based on featured distributions , 1996, Pattern Recognit..

[13]  Andy Liaw,et al.  Classification and Regression by randomForest , 2007 .

[14]  J. Alison Noble,et al.  Integration of Local and Global Features for Anatomical Object Detection in Ultrasound , 2012, MICCAI.

[15]  Max W. K. Law,et al.  Three Dimensional Curvilinear Structure Detection Using Optimally Oriented Flux , 2008, ECCV.

[16]  Vincent Lepetit,et al.  Accurate and Efficient Linear Structure Segmentation by Leveraging Ad Hoc Features with Learned Filters , 2012, MICCAI.

[17]  Max W. K. Law,et al.  Efficient Implementation for Spherical Flux Computation and Its Application to Vascular Segmentation , 2009, IEEE Transactions on Image Processing.

[18]  W. Clem Karl,et al.  Real-time tracking using level sets , 2005, 2005 IEEE Computer Society Conference on Computer Vision and Pattern Recognition (CVPR'05).

[19]  Alauddin Bhuiyan,et al.  An adaptive region growing segmentation for blood vessel detection from retinal images , 2007, VISAPP.

[20]  Alejandro F. Frangi,et al.  Muliscale Vessel Enhancement Filtering , 1998, MICCAI.

[21]  Dorin Comaniciu,et al.  A learning based hierarchical model for vessel segmentation , 2008, 2008 5th IEEE International Symposium on Biomedical Imaging: From Nano to Macro.