Induction of specific T-helper and cytolytic responses to epitopes displayed on a virus-like protein scaffold derived from the pyruvate dehydrogenase multienzyme complex.
暂无分享,去创建一个
D. Piatier‐Tonneau | J. Guardiola | R. Perham | M. Bäckström | R. Sartorius | P. De Berardinis | P. Barba | A. Caivano | G. Domingo | Rossella Sartorius
[1] A. Hill,et al. Enhanced CD8 T cell immunogenicity and protective efficacy in a mouse malaria model using a recombinant adenoviral vaccine in heterologous prime-boost immunisation regimes. , 2002, Vaccine.
[2] R. Ward,et al. Comparison of phage pIII, pVIII and GST as carrier proteins for peptide immunisation in Balb/c mice. , 2001, Immunology letters.
[3] J. Guardiola,et al. Design of cassette vectors permitting cloning of all types of human TCR variable α and β regions , 2001 .
[4] R. Perham,et al. Multiple display of peptides and proteins on a macromolecular scaffold derived from a multienzyme complex. , 2001, Journal of molecular biology.
[5] A. Hill,et al. Vaccines against intracellular infections requiring cellular immunity , 2000, Nature.
[6] J. Guardiola,et al. Phage display of peptide epitopes from HIV-1 elicits strong cytolytic responses , 2000, Nature Biotechnology.
[7] R. Perham,et al. Swinging arms and swinging domains in multifunctional enzymes: catalytic machines for multistep reactions. , 2000, Annual review of biochemistry.
[8] M. Plebanski,et al. Induction of CD8+ T cells using heterologous prime‐boost immunisation strategies , 1999, Immunological reviews.
[9] J. Guardiola,et al. Recognition of HIV-derived B and T cell epitopes displayed on filamentous phages. , 1999, Vaccine.
[10] W G Hol,et al. Principles of quasi-equivalence and Euclidean geometry govern the assembly of cubic and dodecahedral cores of pyruvate dehydrogenase complexes. , 1999, Proceedings of the National Academy of Sciences of the United States of America.
[11] R. Perham,et al. Expression of genes encoding the E2 and E3 components of the Bacillus stearothermophilus pyruvate dehydrogenase complex and the stoichiometry of subunit interaction in assembly in vitro. , 1998, European journal of biochemistry.
[12] A. Westphal,et al. The pyruvate dehydrogenase multi-enzyme complex from Gram-negative bacteria. , 1998, Biochimica et biophysica acta.
[13] Marion Becker,et al. Enhanced immunogenicity for CD8+ T cell induction and complete protective efficacy of malaria DNA vaccination by boosting with modified vaccinia virus Ankara , 1998, Nature Medicine.
[14] C. Bona,et al. Towards development of T-cell vaccines. , 1998, Immunology today.
[15] E. Domingo,et al. Cytotoxic T-lymphocyte responses to HIV-1 reverse transcriptase (review). , 1998, Viral immunology.
[16] A. Hill,et al. A protein particle vaccine containing multiple malaria epitopes , 1997, Nature Biotechnology.
[17] M. Allen,et al. The catalytic domain of dihydrolipoyl acetyltransferase from the pyruvate dehydrogenase multienzyme complex of Bacillus stearothermophilus , 1997, FEBS letters.
[18] F. Lemonnier,et al. HLA-A2.1–restricted Education and Cytolytic Activity of CD8+ T Lymphocytes from β2 Microglobulin (β2m) HLA-A2.1 Monochain Transgenic H-2Db β2m Double Knockout Mice , 1997, The Journal of experimental medicine.
[19] J. Guardiola,et al. Antigenicity of HIV‐derived T helper determinants in the context of carrier recombinant proteins: effect on T helper cell repertoire selection , 1996, European journal of immunology.
[20] J. Borg,et al. Human immunodeficiency virus‐1 reverse transcriptase immunodominant CD4+ T cell epitopes: A peptide‐based multiparametric assessment in the mouse , 1994, European journal of immunology.
[21] A. Kingsman,et al. Induction of HIV-specific cytotoxic T lymphocytes in vivo with hybrid HIV-1 V3:Ty-virus-like particles. , 1993, Journal of immunology.
[22] J. Ulmer,et al. Heterologous protection against influenza by injection of DNA encoding a viral protein. , 1993, Science.
[23] R. Perham. Domains, motifs, and linkers in 2-oxo acid dehydrogenase multienzyme complexes: a paradigm in the design of a multifunctional protein. , 1991, Biochemistry.
[24] A. Kingsman,et al. The expression of hybrid HIV:Ty virus-like particles in yeast , 1987, Nature.
[25] J. Finch,et al. Structure and symmetry of B. stearothermophilus pyruvate dehydrogenase multienzyme complex and implications for eucaryote evolution , 1979, Cell.