CLINICO HEMATOLOGICAL PROFILE OF ACUTE MEGAKARYOBLASTIC LEUKEMIA: REPORT OF FIVE CASES

Acute Megkaryoblastic Leukemia (AMKL) is a rare entity accounting for 1-2% of all Acute myeloblastic Leukemia (AML) (1). It is known as a distinct entity since a very long time but still difficult to diagnose correctly due to lack of distinct clinical features and morphological criteria. Here we present the clinical, morphological, cytochemical features of five cases of AMKL. Certain morphological features such as presence of abnormal platelet count, giant platelets and cytoplasmic blebbing in blasts were found to be important pointers towards the diagnosis.