A low-voltage low-power multi-channel neural interface IC using level-shifted feedback technology

A low-voltage low-power 16-channel neural interface front-end IC for in-vivo neural recording applications is presented in this paper. A current reuse telescope amplifier is used to achieve better noise efficiency factor (NEF). Power efficiency factor (PEF) is further improved by reducing supply voltage with the proposed level-shifted feedback (LSFB) technique. The neural interface is fabricated in a 65 nm CMOS process. It operates under 0.6V supply voltage consuming 1.07 μW/channel. An input referred noise of 5.18 μV is measured, leading to a NEF of 2.94 and a PEF of 5.19 over 10 kHz bandwidth.