Canine dilated cardiomyopathy: a retrospective study of signalment, presentation and clinical findings in 369 cases.

OBJECTIVE To review the clinical and diagnostic findings and survival of dilated cardiomyopathy from a large population of dogs in England. METHODS A retrospective study of the case records of dogs with dilated cardiomyopathy collected between January 1993 and May 2006. RESULTS There were 369 dogs with dilated cardiomyopathy of which all were pure-bred dogs except for four. The most commonly affected breeds were dobermanns and boxers. Over 95 per cent of dogs weighed more than 15 kg and 73 per cent were male. The median duration of signs before referral was three weeks with 65 per cent presenting in stage 3 heart failure. The most common signs were breathlessness (67 per cent) and coughing (64 per cent). The majority of dogs (89 per cent) had an arrhythmia at presentation and 74 per cent of dogs had radiographic signs of pulmonary oedema or pleural effusion. The median survival time was 19 weeks. CLINICAL SIGNIFICANCE Dilated cardiomyopathy occurs primarily in medium to large breed pure-bred dogs, and males are more frequently affected than females. The duration of clinical signs before referral is often short and the survival times are poor. Greater awareness of affected breeds, clinical signs and diagnostic findings may help in early recognition of this disease which often has a short clinical phase.

[1]  Jens Häggström,et al.  Allometric scaling of M-mode cardiac measurements in normal adult dogs. , 2004, Journal of veterinary internal medicine.

[2]  A. Vollmar Use of echocardiography in the diagnosis of dilated cardiomyopathy in Irish wolfhounds. , 1999, Journal of the American Animal Hospital Association.

[3]  J. Boon Manual of Veterinary Echocardiography , 1998 .

[4]  R. S. Wyburn,et al.  A cardiomyopathy in the English Cocker Spaniel: a clinico-pathological investigation , 1982 .

[5]  J. Woodfield Controlled clinical evaluation of enalapril in dogs with heart failure: results of the Cooperative Veterinary Enalapril Study Group. The COVE Study Group. , 1995, Journal of veterinary internal medicine.

[6]  L. Freeman,et al.  Idiopathic dilated cardiomyopathy in Dalmatians: nine cases (1990-1995). , 1996, Journal of the American Veterinary Medical Association.

[7]  Matthew W. Miller,et al.  Clinical, echocardiographic, and electrocardiographic abnormalities in Boxers with cardiomyopathy and left ventricular systolic dysfunction: 48 cases (1985-2003). , 2005, Journal of the American Veterinary Medical Association.

[8]  A. Boswood,et al.  The effect of heart disease, heart failure and diuresis on selected laboratory and electrocardiographic parameters in dogs. , 2006, Journal of veterinary cardiology : the official journal of the European Society of Veterinary Cardiology.

[9]  Calvert Ca,et al.  Congestive cardiomyopathy in Doberman pinscher dogs. , 1982 .

[10]  J. Brown,et al.  Signalment, survival, and prognostic factors in Doberman pinschers with end-stage cardiomyopathy. , 1997, Journal of veterinary internal medicine.

[11]  A. Tidholm Survival in dogs with dilated cardiomyopathy and congestive heart failure treated with digoxin, furosemide and propranolol: A retrospective study of 62 dogs. , 2006, Journal of veterinary cardiology : the official journal of the European Society of Veterinary Cardiology.

[12]  P. Henthorn,et al.  Dilated Cardiomyopathy in Juvenile Portuguese Water Dogs , 2002, Journal of veterinary internal medicine.

[13]  C. Sylvén,et al.  Survival and prognostic factors in 189 dogs with dilated cardiomyopathy. , 1997, Journal of the American Animal Hospital Association.

[14]  M. Salman,et al.  Idiopathic dilated cardiomyopathy in dogs: survival and prognostic indicators. , 1995, Journal of veterinary internal medicine.

[15]  M. O'Sullivan,et al.  Dilated cardiomyopathy: an update. , 2004, The Veterinary clinics of North America. Small animal practice.

[16]  Alessandro Mannelli,et al.  Prognostic indicators for dogs with dilated cardiomyopathy. , 2006, Journal of veterinary internal medicine.

[17]  J W Buchanan,et al.  Vertebral scale system to measure canine heart size in radiographs. , 1995, Journal of the American Veterinary Medical Association.

[18]  R. Thomas Congestive cardiac failure in young Cocker Spaniels (a form of cardiomyopathy?): details of eight cases , 1987 .

[19]  A. Petrič,et al.  Dilated cardiomyopathy in Doberman Pinschers: Survival, Causes of Death and a Pedigree Review in a Related Line. , 2002, Journal of veterinary cardiology : the official journal of the European Society of Veterinary Cardiology.

[20]  M. Cobb,et al.  Observations on the development of congestive heart failure in Irish wolfhounds with dilated cardiomyopathy. , 1999, The Journal of small animal practice.

[21]  N. Fowler,et al.  Primary Myocardial Disease , 1961, Diseases of the chest.

[22]  N. Wright,et al.  Clinical features of dilated cardiomyopathy in Great Danes and results of a pedigree analysis: 17 cases (1990-2000). , 2001, Journal of the American Veterinary Medical Association.