Calibration-Free Gait Assessment by Foot-Worn Inertial Sensors

Walking is a central activity of daily life, and there is an increasing demand for objective measurement-based gait assessment. In contrast to stationary systems, wearable inertial measurement units (IMUs) have the potential to enable non-restrictive and accurate gait assessment in daily life. We propose a set of algorithms that uses the measurements of two foot-worn IMUs to determine major spatiotemporal gait parameters that are essential for clinical gait assessment: durations of five gait phases for each side as well as stride length, walking speed, and cadence. Compared to many existing methods, the proposed algorithms neither require magnetometers nor a precise mounting of the sensor or dedicated calibration movements. They are therefore suitable for unsupervised use by non-experts in indoor as well as outdoor environments. While previously proposed methods are rarely validated in pathological gait, we evaluate the accuracy of the proposed algorithms on a very broad dataset consisting of 215 trials and three different subject groups walking on a treadmill: healthy subjects (n = 39), walking at three different speeds, as well as orthopedic (n = 62) and neurological (n = 36) patients, walking at a self-selected speed. The results show a very strong correlation of all gait parameters (Pearson's r between 0.83 and 0.99, p < 0.01) between the IMU system and the reference system. The mean absolute difference (MAD) is 1.4 % for the gait phase durations, 1.7 cm for the stride length, 0.04 km/h for the walking speed, and 0.7 steps/min for the cadence. We show that the proposed methods achieve high accuracy not only for a large range of walking speeds but also in pathological gait as it occurs in orthopedic and neurological diseases. In contrast to all previous research, we present calibration-free methods for the estimation of gait phases and spatiotemporal parameters and validate them in a large number of patients with different pathologies. The proposed methods lay the foundation for ubiquitous unsupervised gait assessment in daily-life environments.

[1]  Stephanie A. Bridenbaugh,et al.  Laboratory Review: The Role of Gait Analysis in Seniors’ Mobility and Fall Prevention , 2010, Gerontology.

[2]  Sahar Hassani,et al.  Human gait and Clinical Movement Analysis , 2015 .

[3]  Aurelio Cappozzo,et al.  Joint kinematics estimate using wearable inertial and magnetic sensing modules. , 2008, Gait & posture.

[4]  Kamiar Aminian,et al.  3D gait assessment in young and elderly subjects using foot-worn inertial sensors. , 2010, Journal of biomechanics.

[5]  Hermann Schwameder,et al.  Repeatability of spatiotemporal, plantar pressure and force parameters during treadmill walking and running. , 2018, Gait & posture.

[6]  Jeffrey M. Hausdorff,et al.  Estimation of step-by-step spatio-temporal parameters of normal and impaired gait using shank-mounted magneto-inertial sensors: application to elderly, hemiparetic, parkinsonian and choreic gait , 2014, Journal of NeuroEngineering and Rehabilitation.

[7]  A. Achiron,et al.  Quantifying Gait Impairment Using an Instrumented Treadmill in People with Multiple Sclerosis , 2013, ISRN neurology.

[8]  Thomas Seel,et al.  Experimental Evaluation of a Novel Inertial Sensor Based Realtime Gait Phase De-tection Algorithm , 2015 .

[9]  L. Ferrucci,et al.  Trajectories of gait speed predict mortality in well-functioning older adults: the Health, Aging and Body Composition study. , 2013, The journals of gerontology. Series A, Biological sciences and medical sciences.

[10]  Young Soo Suh,et al.  Inertial Sensor-Based Two Feet Motion Tracking for Gait Analysis , 2013, Sensors.

[11]  Michael Lorenz,et al.  Towards Inertial Sensor Based Mobile Gait Analysis: Event-Detection and Spatio-Temporal Parameters , 2018, Sensors.

[12]  Xavier Crevoisier,et al.  Quantitative estimation of foot-flat and stance phase of gait using foot-worn inertial sensors. , 2013, Gait & posture.

[13]  A. Achiron,et al.  Gait analysis in multiple sclerosis: characterization of temporal-spatial parameters using GAITRite functional ambulation system. , 2009, Gait & posture.

[14]  J. Kuipers Quaternions and Rotation Sequences , 1998 .

[15]  J. Allum,et al.  Gait event detection using linear accelerometers or angular velocity transducers in able-bodied and spinal-cord injured individuals. , 2006, Gait & posture.

[16]  Edward D. Lemaire,et al.  Temporal-spatial gait parameter models of very slow walking. , 2018, Gait & posture.

[17]  Thomas Seel,et al.  Automatic anatomical calibration for IMU-based elbow angle measurement in disturbed magnetic fields , 2017 .

[18]  Bernd Markert,et al.  A systematic review of gait analysis methods based on inertial sensors and adaptive algorithms. , 2017, Gait & posture.

[19]  Jay Dicharry,et al.  A three-dimensional kinematic and kinetic comparison of overground and treadmill walking in healthy elderly subjects. , 2010, Clinical biomechanics.

[20]  J. Hidler,et al.  Biomechanics of overground vs. treadmill walking in healthy individuals. , 2008, Journal of applied physiology.

[21]  S. Studenski,et al.  Gait speed and survival in older adults. , 2011, JAMA.

[22]  T. W. Ridler,et al.  Picture thresholding using an iterative selection method. , 1978 .

[23]  R. Baker Gait analysis methods in rehabilitation , 2006, Journal of NeuroEngineering and Rehabilitation.

[24]  B. Zörner,et al.  Familiarization with treadmill walking: How much is enough? , 2019, Scientific Reports.

[25]  Markus Valtin,et al.  Mobil4Park: development of a sensor-stimulator network for the therapy of freezing of gait in Parkinson patients , 2020, Current Directions in Biomedical Engineering.

[26]  Andrea Mannini,et al.  Gait phase detection and discrimination between walking-jogging activities using hidden Markov models applied to foot motion data from a gyroscope. , 2012, Gait & posture.

[27]  Scott C Wearing,et al.  Agreement between temporal and spatial gait parameters from an instrumented walkway and treadmill system at matched walking speed. , 2013, Gait & posture.

[28]  Angelo M. Sabatini,et al.  Assessment of walking features from foot inertial sensing , 2005, IEEE Transactions on Biomedical Engineering.

[29]  Y H Chan,et al.  Biostatistics 104: correlational analysis. , 2003, Singapore medical journal.

[30]  Jeffrey M. Hausdorff,et al.  Estimation of spatio-temporal parameters of gait from magneto-inertial measurement units: multicenter validation among Parkinson, mildly cognitively impaired and healthy older adults , 2018, BioMedical Engineering OnLine.

[31]  D. Giavarina Understanding Bland Altman analysis , 2015, Biochemia medica.

[32]  Kathy Martin Measuring Walking: A Handbook of Clinical Gait Analysis , 2014 .

[33]  Julius Hannink,et al.  Sensor-Based Gait Parameter Extraction With Deep Convolutional Neural Networks , 2016, IEEE Journal of Biomedical and Health Informatics.

[34]  Steven Y Cen,et al.  Meaningful Gait Speed Improvement During the First 60 Days Poststroke: Minimal Clinically Important Difference , 2010, Physical Therapy.

[35]  Nina Lefeber,et al.  Validity and Reproducibility of Inertial Physilog Sensors for Spatiotemporal Gait Analysis in Patients With Stroke , 2019, IEEE Transactions on Neural Systems and Rehabilitation Engineering.

[36]  Giancarlo Ferrigno,et al.  A Novel Adaptive, Real-Time Algorithm to Detect Gait Events From Wearable Sensors , 2015, IEEE Transactions on Neural Systems and Rehabilitation Engineering.

[37]  Justin C. Brown,et al.  Walking Cadence and Mortality Among Community-Dwelling Older Adults , 2014, Journal of general internal medicine.

[38]  Thomas Seel,et al.  IMU-Based Joint Angle Measurement for Gait Analysis , 2014, Sensors.

[39]  Richard W. Bohannon Minimal clinically important difference for change in comfortable gait speed of adults with pathology: a systematic review , 2014 .

[40]  K. Kragholm,et al.  Validity of the GAITRite Walkway Compared to Functional Balance Tests for Fall Risk Assessment in Geriatric Outpatients , 2020, Geriatrics.

[41]  Martina Minnerop,et al.  Accuracy and repeatability of two methods of gait analysis - GaitRite™ und Mobility Lab™ - in subjects with cerebellar ataxia. , 2016, Gait & posture.

[42]  Chris J. Hass,et al.  Quantitative Normative Gait Data in a Large Cohort of Ambulatory Persons with Parkinson’s Disease , 2012, PloS one.

[43]  Angelo M. Sabatini,et al.  Online Decoding of Hidden Markov Models for Gait Event Detection Using Foot-Mounted Gyroscopes , 2014, IEEE Journal of Biomedical and Health Informatics.

[44]  Corina Nüesch,et al.  Validity and reliability of a portable gait analysis system for measuring spatiotemporal gait characteristics: comparison to an instrumented treadmill , 2016, Journal of NeuroEngineering and Rehabilitation.

[45]  S. Studenski,et al.  Physical Performance Measures in the Clinical Setting , 2003, Journal of the American Geriatrics Society.

[46]  Julius Hannink,et al.  Mobile Stride Length Estimation With Deep Convolutional Neural Networks , 2016, IEEE Journal of Biomedical and Health Informatics.

[47]  J. N. van der Geest,et al.  Unraveling the Association Between Gait and Mortality—One Step at a Time , 2019, The journals of gerontology. Series A, Biological sciences and medical sciences.

[48]  Andrea Mannini,et al.  Fourier-based integration of quasi-periodic gait accelerations for drift-free displacement estimation using inertial sensors , 2015, BioMedical Engineering OnLine.

[49]  Kamiar Aminian,et al.  Heel and Toe Clearance Estimation for Gait Analysis Using Wireless Inertial Sensors , 2012, IEEE Transactions on Biomedical Engineering.

[50]  Tae-ho Kim,et al.  The effects of balance and gait function on quality of life of stroke patients. , 2019, NeuroRehabilitation.

[51]  R. Lipton,et al.  Quantitative gait markers and incident fall risk in older adults. , 2009, The journals of gerontology. Series A, Biological sciences and medical sciences.

[52]  E. Amaro,et al.  Factors associated with lower gait speed among the elderly living in a developing country: a cross-sectional population-based study , 2015, BMC Geriatrics.

[53]  Teresa Blanco,et al.  Gait Analysis in a Box: A System Based on Magnetometer-Free IMUs or Clusters of Optical Markers with Automatic Event Detection , 2020, Sensors.

[54]  Kamiar Aminian,et al.  On-Shoe Wearable Sensors for Gait and Turning Assessment of Patients With Parkinson's Disease , 2013, IEEE Transactions on Biomedical Engineering.

[55]  Chandramouli Krishnan,et al.  Validity and repeatability of inertial measurement units for measuring gait parameters. , 2017, Gait & posture.

[56]  B. E. Maki,et al.  Gait Changes in Older Adults: Predictors of Falls or Indicators of Fear? , 1997, Journal of the American Geriatrics Society.

[57]  S. Õunpuu,et al.  Clinical efficacy of instrumented gait analysis: Systematic review 2020 update. , 2020, Gait & posture.

[58]  M. Inzitari,et al.  Gait speed at usual pace as a predictor of adverse outcomes in community-dwelling older people an International Academy on Nutrition and Aging (IANA) Task Force , 2009, The journal of nutrition, health & aging.

[59]  F. V. D. van der Helm,et al.  Magnetic distortion in motion labs, implications for validating inertial magnetic sensors. , 2009, Gait & posture.

[60]  Guang-Zhong Yang,et al.  Towards Pervasive Gait Analysis for Medicine with Wearable Sensors: A Systematic Review for Clinicians and Medical Researchers. , 2016, IEEE journal of biomedical and health informatics.

[61]  Angelo M. Sabatini,et al.  Hidden Markov model-based strategy for gait segmentation using inertial sensors: Application to elderly, hemiparetic patients and Huntington's disease patients , 2015, 2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC).

[62]  D Kotiadis,et al.  Inertial Gait Phase Detection for control of a drop foot stimulator Inertial sensing for gait phase detection. , 2010, Medical engineering & physics.

[63]  Qingguo Li,et al.  Inertial Sensor-Based Methods in Walking Speed Estimation: A Systematic Review , 2012, Sensors.

[64]  Georg Rose,et al.  Feasibility of a Sensor-Based Gait Event Detection Algorithm for Triggering Functional Electrical Stimulation during Robot-Assisted Gait Training , 2019, Sensors.

[65]  R. Craik,et al.  Determining meaningful changes in gait speed after hip fracture. , 2006, Physical therapy.

[66]  Björn Eskofier,et al.  Inertial Sensor-Based Stride Parameter Calculation From Gait Sequences in Geriatric Patients , 2015, IEEE Transactions on Biomedical Engineering.

[67]  Thomas Seel,et al.  Automatic pairing of inertial sensors to lower limb segments – a plug-and-play approach , 2016 .

[68]  Roman Kusche,et al.  A Portable In-Ear Pulse Wave Measurement System , 2020 .

[69]  S. Studenski,et al.  Gait characteristics associated with walking speed decline in older adults: results from the Baltimore Longitudinal Study of Aging. , 2015, Archives of gerontology and geriatrics.