On the benefit of bivalency in peptide ligand/pin1 interactions.
暂无分享,去创建一个
Sebastian Daum | C. Schiene‐Fischer | Sebastian Daum | D. Wildemann | Christian Lücke | Cordelia Schiene-Fischer | Dirk Wildemann | C. Lücke
[1] L. Mayr,et al. Structural Analysis of the Mitotic Regulator hPin1 in Solution , 2003, Journal of Biological Chemistry.
[2] S. Esnault,et al. The peptidyl-prolyl isomerase Pin1 regulates the stability of granulocyte-macrophage colony-stimulating factor mRNA in activated eosinophils , 2005, Nature Immunology.
[3] K. Lu,et al. Pinning down phosphorylated tau and tauopathies. , 2005, Biochimica et biophysica acta.
[4] D. Litchfield,et al. Interactions between Protein Kinase CK2 and Pin1 , 2002, The Journal of Biological Chemistry.
[5] A. J. Kirby,et al. Effective Molarities for Intramolecular Reactions , 1980 .
[6] P. Schimmel,et al. Conformational energy and configurational statistics of poly-L-proline. , 1967, Proceedings of the National Academy of Sciences of the United States of America.
[7] T. Gemmill,et al. Vanishingly Low Levels of Ess1 Prolyl-isomerase Activity Are Sufficient for Growth in Saccharomyces cerevisiae* , 2005, Journal of Biological Chemistry.
[8] P. Carlier,et al. Development of bivalent acetylcholinesterase inhibitors as potential therapeutic drugs for Alzheimer's disease. , 2004, Current pharmaceutical design.
[9] R. Huber,et al. Bivalency as a principle for proteasome inhibition. , 1999, Proceedings of the National Academy of Sciences of the United States of America.
[10] George M Whitesides,et al. Polyvalent Interactions in Biological Systems: Implications for Design and Use of Multivalent Ligands and Inhibitors. , 1998, Angewandte Chemie.
[11] K. Lu,et al. Phosphorylation-dependent prolyl isomerization: a novel cell cycle regulatory mechanism. , 2000, Progress in cell cycle research.
[12] Bailing Xu,et al. Conformationally locked isostere of phosphoSer-cis-Pro inhibits Pin1 23-fold better than phosphoSer-trans-Pro isostere. , 2004, Journal of the American Chemical Society.
[13] U. Reimer,et al. Role of phosphorylation in determining the backbone dynamics of the serine/threonine-proline motif and Pin1 substrate recognition. , 1998, Biochemistry.
[14] Tianhua Niu,et al. Pin1 is overexpressed in breast cancer and cooperates with Ras signaling in increasing the transcriptional activity of c‐Jun towards cyclin D1 , 2001, The EMBO journal.
[15] W. Atkins,et al. Novel class of bivalent glutathione S-transferase inhibitors. , 2003, Biochemistry.
[16] K. Lu. Pinning down cell signaling, cancer and Alzheimer's disease. , 2004, Trends in biochemical sciences.
[17] Tony Hunter,et al. Structural basis for phosphoserine-proline recognition by group IV WW domains , 2000, Nature Structural Biology.
[18] K. Sharp,et al. Protein folding and association: Insights from the interfacial and thermodynamic properties of hydrocarbons , 1991, Proteins.
[19] E. Hulme,et al. Receptor-ligand interactions : a practical approach , 1992 .
[20] W. Eaton,et al. Polyproline and the "spectroscopic ruler" revisited with single-molecule fluorescence. , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[21] R. Ranganathan,et al. Structural and Functional Analysis of the Mitotic Rotamase Pin1 Suggests Substrate Recognition Is Phosphorylation Dependent , 1997, Cell.
[22] P. Davies,et al. The prolyl isomerase Pin1 restores the function of Alzheimer-associated phosphorylated tau protein , 1999, Nature.
[23] M. Kirschner,et al. Pin1 acts catalytically to promote a conformational change in Cdc25. , 2001, Molecular cell.
[24] Robert A Copeland,et al. Evaluation of enzyme inhibitors in drug discovery. A guide for medicinal chemists and pharmacologists. , 2005, Methods of biochemical analysis.
[25] G Fischer,et al. Pin1-dependent prolyl isomerization regulates dephosphorylation of Cdc25C and tau proteins. , 2000, Molecular cell.
[26] T. Hunter,et al. A human peptidyl–prolyl isomerase essential for regulation of mitosis , 1996, Nature.
[27] A. Ryo,et al. Regulation of NF-kappaB signaling by Pin1-dependent prolyl isomerization and ubiquitin-mediated proteolysis of p65/RelA. , 2003, Molecular cell.
[28] T. Warkentin. Bivalent direct thrombin inhibitors: hirudin and bivalirudin. , 2004, Best practice & research. Clinical haematology.
[29] Miquel Pons,et al. Peptide Binding Induces Large Scale Changes in Inter-domain Mobility in Human Pin1* , 2003, Journal of Biological Chemistry.
[30] M. Bowman,et al. Structural basis for high-affinity peptide inhibition of human Pin1. , 2007, ACS chemical biology.
[31] Xiao Zhen Zhou,et al. Nanomolar inhibitors of the peptidyl prolyl cis/trans isomerase Pin1 from combinatorial peptide libraries. , 2006, Journal of medicinal chemistry.
[32] L. Buée,et al. Regulation of Pin1 peptidyl‐prolyl cis/trans isomerase activity by its WW binding module on a multi‐phosphorylated peptide of Tau protein , 2005, FEBS letters.
[33] Xiao Zhen Zhou,et al. Function of WW domains as phosphoserine- or phosphothreonine-binding modules. , 1999, Science.
[34] A. Means,et al. The mitotic peptidyl‐prolyl isomerase, Pin1, interacts with Cdc25 and Plx1 , 1998, The EMBO journal.
[35] Dale F. Mierke,et al. Receptor–Ligand Interactions , 2004 .
[36] A. Traish,et al. The multifunctional nuclear protein p54nrb is multiphosphorylated in mitosis and interacts with the mitotic regulator Pin1. , 2005, Journal of molecular biology.
[37] D. Lawrence,et al. Molecular Rulers: An Assessment of Distance and Spatial Relationships of Src Tyrosine Kinase SH2 and Active Site Regions* , 2001, The Journal of Biological Chemistry.
[38] Xiao Zhen Zhou,et al. Pin1 modulates the structure and function of human RNA polymerase II. , 2003, Genes & development.
[39] M. Billeter,et al. MOLMOL: a program for display and analysis of macromolecular structures. , 1996, Journal of molecular graphics.
[40] Tony Hunter,et al. Role of the prolyl isomerase Pin1 in protecting against age-dependent neurodegeneration , 2003, Nature.
[41] Masafumi Nakamura,et al. Pin1 regulates turnover and subcellular localization of β-catenin by inhibiting its interaction with APC , 2001, Nature Cell Biology.
[42] Eric Oldfield,et al. 1H, 13C and 15N chemical shift referencing in biomolecular NMR , 1995, Journal of biomolecular NMR.
[43] Priti Garg,et al. Modeling breast cancer in vivo and ex vivo reveals an essential role of Pin1 in tumorigenesis , 2004, The EMBO journal.
[44] J. Manley,et al. Pinning Down Transcription: Regulation of RNA Polymerase II Activity During the Cell Cycle , 2004, Cell cycle.
[45] C. Schiene‐Fischer,et al. Thermodynamics of phosphopeptide binding to the human peptidyl prolyl cis/trans isomerase Pin1. , 2006, Biochemistry.
[46] Ming Zhou,et al. Regulation of Raf-1 by direct feedback phosphorylation. , 2005, Molecular cell.
[47] T. Hsu,et al. Drosophila Pin1 prolyl isomerase Dodo is a MAP kinase signal responder during oogenesis , 2001, Nature Cell Biology.
[48] K. Fiebig,et al. Letter to the Editor: 1H, 13C and 15N backbone resonance assignment of the peptidyl-prolyl cis-trans isomerase Pin1 , 2002, Journal of Biomolecular NMR.
[49] R. Boelens,et al. Altered flexibility in the substrate-binding site of related native and engineered high-alkaline Bacillus subtilisins. , 1999, Journal of molecular biology.
[50] W. Jencks,et al. On the attribution and additivity of binding energies. , 1981, Proceedings of the National Academy of Sciences of the United States of America.
[51] L. Buée,et al. 1H NMR Study on the Binding of Pin1 Trp-Trp Domain with Phosphothreonine Peptides* , 2001, The Journal of Biological Chemistry.
[52] Y. Cheng,et al. Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction. , 1973, Biochemical pharmacology.
[53] D. Osguthorpe,et al. Structure and energetics of ligand binding to proteins: Escherichia coli dihydrofolate reductase‐trimethoprim, a drug‐receptor system , 1988, Proteins.
[54] S. Murray,et al. The prolyl isomerase Pin1 is a regulator of p53 in genotoxic response , 2002, Nature.
[55] M. Schutkowski,et al. A protease-free assay for peptidyl prolyl cis/trans isomerases using standard peptide substrates. , 1997, Analytical biochemistry.
[56] A. Means,et al. Requirement of the prolyl isomerase Pin1 for the replication checkpoint. , 2000, Science.