Autism spectrum disorder (ASD) and its perioperative management

Autism spectrum disorder (ASD) is now diagnosed in more than 1 in 100 children, so it is not surprising that anesthetists are increasingly providing care for children with this diagnosis. The diagnostic classification for ASD has recently changed and our understanding of the causes and management of ASD are also changing rapidly. This review provides a timely update to increase understanding and awareness of the problems that children with ASD experience, and to minimize perioperative problems. Current literature on premedication and the increasing use of alpha‐2 agonists such as clonidine and dexmedetomidine as well as the use of old favorites midazolam and ketamine is reviewed. Some simple strategies that will improve care and decrease anxiety, like social stories, the use of tablet computers, other comfort items or games for distraction, and using favorite drinks to disguise the bitter taste of medications, are described. Remember, the parents are their child's expert and will know what agitates and settles them. Talking to them prior to the day of the procedure is ideal. The importance of staff training and having a clinical practice guideline available at every institution cannot be overstated.

[1]  M. Blitz,et al.  Management of the uncooperative child. , 2010, Oral and maxillofacial surgery clinics of North America.

[2]  B. Peretz,et al.  The use of restraint in the treatment of paediatric dental patients: old and new insights. , 2002, International journal of paediatric dentistry.

[3]  Heather Cody Hazlett,et al.  Moderate sedation for MRI in young children with autism , 2005, Pediatric Radiology.

[4]  P. Bolton,et al.  Epilepsy in autism: features and correlates , 2011, British Journal of Psychiatry.

[5]  A. Cromhout Ketamine: its use in the emergency department. , 2003, Emergency medicine.

[6]  Kim Van Naarden Braun,et al.  Trends in the Prevalence of Autism Spectrum Disorder, Cerebral Palsy, Hearing Loss, Intellectual Disability, and Vision Impairment, Metropolitan Atlanta, 1991–2010 , 2015, PloS one.

[7]  D. Skuse Asperger's Syndrome: A Guide for Parents and Professionals , 1998 .

[8]  Judith Alison Short,et al.  Anaesthesia for children with special needs, including autistic spectrum disorder , 2013 .

[9]  K. Bachenberg Oral ketamine for the management of combative autistic adult. , 1998, Anesthesiology.

[10]  John J. Connolly,et al.  The Genetics of Autism Spectrum Disorders , 2011 .

[11]  B. Petty,et al.  Perioperative medication management. , 2003, The Medical clinics of North America.

[12]  J. Baio,et al.  Prevalence of Autism Spectrum Disorders: Autism and Developmental Disabilities Monitoring Network, United States, 2006. Morbidity and Mortality Weekly Report. Surveillance Summaries. Volume 58, Number SS-10. , 2009 .

[13]  Erik T Parner,et al.  Patterns of Contact with Hospital for Children with an Autism Spectrum Disorder: A Danish Register-Based Study , 2011, Journal of Autism and Developmental Disorders.

[14]  T Loucas,et al.  IQ in children with autism spectrum disorders: data from the Special Needs and Autism Project (SNAP) , 2010, Psychological Medicine.

[15]  R. Delorme,et al.  Psychiatric and psychosocial problems in adults with normal-intelligence autism spectrum disorders , 2009, BMC psychiatry.

[16]  M. Lumley,et al.  Anger Management , 2020, Encyclopedia of Behavioral Medicine.

[17]  Pat Mirenda,et al.  Developmental trajectories of symptom severity and adaptive functioning in an inception cohort of preschool children with autism spectrum disorder. , 2015, JAMA psychiatry.

[18]  Juane Heflin,et al.  Students with Autism Spectrum Disorders : Effective Instructional Practices , 2007 .

[19]  Johnny L. Matson,et al.  Review of gender differences in core symptomatology in autism spectrum disorders , 2011 .

[20]  J. Drake,et al.  Evaluation of a Coping Kit of Items to Support Children with Developmental Disorders in the Hospital Setting , 2012 .

[21]  X. Ming,et al.  Use of clonidine in children with autism spectrum disorders , 2008, Brain and Development.

[22]  H. Meltzer,et al.  Epidemiology of autism spectrum disorders in adults in the community in England. , 2011, Archives of general psychiatry.

[23]  D. Skuse,et al.  Sex Differences in Autism Spectrum Disorder: Evidence from a Large Sample of Children and Adolescents , 2011, Journal of Autism and Developmental Disorders.

[24]  J. H. Van Der Walt,et al.  An audit of perioperative management of autistic children , 2001, Paediatric anaesthesia.

[25]  C. Loo,et al.  Behaviour guidance in dental treatment of patients with autism spectrum disorder. , 2009, International journal of paediatric dentistry.

[26]  A. Brereton,et al.  Autism: Fifty years on from Kanner , 1994, Journal of paediatrics and child health.

[27]  P. Szatmari The causes of autism spectrum disorders , 2003, BMJ : British Medical Journal.

[28]  N. Rinehart,et al.  A Clinical and Neurobehavioural Review of High-Functioning Autism and Asperger's Disorder , 2002, The Australian and New Zealand journal of psychiatry.

[29]  A. Petros Oral ketamine. Its use for mentally retarded adults requiring day care dental treatment. , 1991, Anaesthesia.

[30]  J. Berkenbosch,et al.  Preliminary experience with oral dexmedetomidine for procedural and anesthetic premedication , 2005, Paediatric anaesthesia.

[31]  C. Gillberg,et al.  Autism phenotype versus registered diagnosis in Swedish children: prevalence trends over 10 years in general population samples , 2015, BMJ : British Medical Journal.

[32]  UDAY C. MEHTA,et al.  EEG Sedation for Children with Autism , 2004, Journal of developmental and behavioral pediatrics : JDBP.

[33]  S. Courtman,et al.  Children with learning disabilities , 2008, Paediatric anaesthesia.

[34]  M. Prior,et al.  Autism in context 1: Classification, counting and causes , 2014, Journal of paediatrics and child health.

[35]  K. Williams,et al.  The prevalence of autism in Australia. Can it be established from existing data? , 2008, Journal of paediatrics and child health.

[36]  L Rainey,et al.  The Anaesthetic Management of Autistic Children , 1998, Anaesthesia and intensive care.

[37]  Irene Vaz,et al.  Visual symbols in healthcare settings for children with learning disabilities and autism spectrum disorder. , 2013, British journal of nursing.

[38]  J. Tobias,et al.  Dexmedetomidine for sedation during electroencephalographic analysis in children with autism, pervasive developmental disorders, and seizure disorders. , 2008, Journal of clinical anesthesia.

[39]  J. Berkenbosch,et al.  Dexmedetomidine for procedural sedation in children with autism and other behavior disorders. , 2009, Pediatric neurology.

[40]  G. Baird,et al.  Psychiatric disorders in children with autism spectrum disorders: prevalence, comorbidity, and associated factors in a population-derived sample. , 2008, Journal of the American Academy of Child and Adolescent Psychiatry.

[41]  G. Baird,et al.  Management of autism in children and young people: summary of NICE and SCIE guidance , 2013, BMJ.

[42]  J. Slaets,et al.  Psychotropic drugs and the perioperative period: a proposal for a guideline in elective surgery. , 2006, Psychosomatics.

[43]  Y. S. Kim,et al.  Global Prevalence of Autism and Other Pervasive Developmental Disorders , 2012, Autism research : official journal of the International Society for Autism Research.

[44]  P. Filipek,et al.  Intervention for autistic spectrum disorders , 2006, NeuroRX.

[45]  T. Martin,et al.  Combination of oral ketamine and midazolam as a premedication for a severely autistic and combative patient , 2009, Journal of Anesthesia.

[46]  Elaine Christiansen,et al.  Induction of anesthesia in a combative child; management and issues , 2005, Paediatric anaesthesia.

[47]  Norah L. Johnson,et al.  Evaluation of a coping kit for children with challenging behaviors in a pediatric hospital. , 2012, Pediatric nursing.

[48]  Christopher M. Whinney Perioperative medication management: General principles and practical applications , 2009, Cleveland Clinic Journal of Medicine.