Activities of total, cytoplasmic, and mitochondrial superoxide dismutase enzymes in sera and pleural fluids from patients with lung cancer

In this study, total cytoplasmic (Cu, Zn‐SOD) and mitochondrial (Mn‐SOD) superoxide dismutase activities were measured in sera and pleural fluids from patients with squamous cell carcinoma of the lung. The results were compared with those of control subjects and those of patients with tuberculosis and chronic heart failure. Serum activities were found higher in all patient groups compared to control group. Highest values were however in tuberculosis group. In the correlation analysis, meaningful intra‐ and inter‐correlations were established between enzyme activities in the samples.

[1]  İ. Durak,et al.  Serum adenosine deaminase and total superoxide dismutase activities before and after surgical removal of cancerous laryngeal tissue , 1994, The Journal of Laryngology & Otology.

[2]  J. Prolla,et al.  Pleural Fluid Adenosine Deaminase and Lymphocyte Proportion: Clinical Usefulness In the Diagnosis of Tuberculosis , 1994, Cytopathology : official journal of the British Society for Clinical Cytology.

[3]  S. Büyükberber,et al.  Mn- and Cu,Zn-superoxide dismutase activities during acute myocardial infarction. , 1993, Clinical chemistry.

[4]  İ. Durak,et al.  A methodological approach to superoxide dismutase (SOD) activity assay based on inhibition of nitroblue tetrazolium (NBT) reduction. , 1993, Clinica chimica acta; international journal of clinical chemistry.

[5]  J. Kwee,et al.  Lowered superoxide dismutase in highly metastatic B16 melanoma cells. , 1991, Cancer letters.

[6]  D. Goeddel,et al.  Induction of manganous superoxide dismutase by tumor necrosis factor: possible protective mechanism , 1988, Science.

[7]  Y. Sun,et al.  A simple method for clinical assay of superoxide dismutase. , 1988, Clinical chemistry.

[8]  F. Paoletti,et al.  A sensitive spectrophotometric method for the determination of superoxide dismutase activity in tissue extracts. , 1986, Analytical biochemistry.

[9]  L. Schacter,et al.  Red cell superoxide dismutase and sickle cell anemia symptom severity , 1985, American journal of hematology.

[10]  T. Kamada,et al.  Chemiluminescence and superoxide dismutase in the plasma in patients with alcoholic and non-alcoholic liver injuries. , 1985, Alcohol.

[11]  A. Berry,et al.  Blood levels of superoxide dismutase and glutathione peroxidase in Duchenne muscular dystrophy. , 1980, Clinica chimica acta; international journal of clinical chemistry.

[12]  I. Fridovich,et al.  Superoxide dismutase. An enzymic function for erythrocuprein (hemocuprein). , 1969, The Journal of biological chemistry.

[13]  N. Taniguchi,et al.  High levels of Mn-superoxide dismutase in serum of patients with neuroblastoma and in human neuroblastoma cell lines. , 1992, Free radical biology & medicine.

[14]  Lan-kai-wei.  The clinical and laboratory studies of superoxide dismutase activity in the human whole blood with early gastric cancer. , 1991 .