Distal sequences, but not ori-beta/OBR-1, are essential for initiation of DNA replication in the Chinese hamster DHFR origin.

[1]  G. Wahl,et al.  Genetic dissection of a mammalian replicator in the human beta-globin locus. , 1998, Science.

[2]  M. DePamphilis,et al.  Identification of Primary Initiation Sites for DNA Replication in the Hamster Dihydrofolate Reductase Gene Initiation Zone , 1998, Molecular and Cellular Biology.

[3]  P. Dijkwel,et al.  Lagging-Strand, Early-Labelling, and Two-Dimensional Gel Assays Suggest Multiple Potential Initiation Sites in the Chinese Hamster Dihydrofolate Reductase Origin , 1998, Molecular and Cellular Biology.

[4]  Elaine R. Mardis,et al.  In Genome analysis: A laboratory manual , 1997 .

[5]  M. Giacca,et al.  High-resolution mapping of the origin of DNA replication in the hamster dihydrofolate reductase gene domain by competitive PCR , 1996, Molecular and cellular biology.

[6]  J. Hamlin,et al.  Composite patterns in neutral/neutral two-dimensional gels demonstrate inefficient replication origin usage , 1996, Molecular and cellular biology.

[7]  P. Dijkwel,et al.  Characterizing replication intermediates in the amplified CHO dihydrofolate reductase domain by two novel gel electrophoretic techniques , 1996, Molecular and cellular biology.

[8]  M. Méchali,et al.  Transition in Specification of Embryonic Metazoan DNA Replication Origins , 1995, Science.

[9]  A. Carothers,et al.  Non-random deletions at the dihydrofolate reductase locus of Chinese hamster ovary cells induced by alpha-particles simulating radon. , 1995, Carcinogenesis.

[10]  P. Dijkwel,et al.  The Chinese hamster dihydrofolate reductase origin consists of multiple potential nascent-strand start sites , 1995, Molecular and cellular biology.

[11]  P. Dijkwel,et al.  On the nature of replication origins in higher eukaryotes. , 1995, Current opinion in genetics & development.

[12]  P. Dijkwel,et al.  Replication initiation sites are distributed widely in the amplified CHO dihydrofolate reductase domain. , 1994, Nucleic acids research.

[13]  T. Shinomiya,et al.  Mapping an initiation region of DNA replication at a single-copy chromosomal locus in Drosophila melanogaster cells by two-dimensional gel methods and PCR-mediated nascent-strand analysis: multiple replication origins in a broad zone , 1994, Molecular and cellular biology.

[14]  J. Huberman,et al.  Three ARS elements contribute to the ura4 replication origin region in the fission yeast, Schizosaccharomyces pombe. , 1994, The EMBO journal.

[15]  L. Zentilin,et al.  Fine mapping of a replication origin of human DNA. , 1994, Proceedings of the National Academy of Sciences of the United States of America.

[16]  S. Haase,et al.  Transcription inhibits the replication of autonomously replicating plasmids in human cells , 1994, Molecular and cellular biology.

[17]  W. Burhans,et al.  DNA replication origins in animal cells: a question of context? , 1994, Science.

[18]  W. L. Fangman,et al.  Initiation at closely spaced replication origins in a yeast chromosome. , 1993, Science.

[19]  H. Cedar,et al.  Replication structure of the human & beta;-globin gene domain , 1993, Nature.

[20]  R. D. Little,et al.  Initiation and termination of DNA replication in human rRNA genes , 1993, Molecular and cellular biology.

[21]  T. Shinomiya,et al.  DNA replication of histone gene repeats in Drosophila melanogaster tissue culture cells: multiple initiation sites and replication pause sites , 1993, Molecular and cellular biology.

[22]  C. Price.  Fluorescence in situ hybridization. , 1993, Blood reviews.

[23]  H. Smith,et al.  Replication initiates at a confined region during DNA amplification in Sciara DNA puff II/9A. , 1993, Genes & development.

[24]  M. DePamphilis.  Eukaryotic DNA replication: anatomy of an origin. , 1993, Annual review of biochemistry.

[25]  P. Dijkwel,et al.  The plant amino acid mimosine may inhibit initiation at origins of replication in Chinese hamster cells , 1992, Molecular and cellular biology.

[26]  P. Dijkwel,et al.  Initiation of DNA replication in the dihydrofolate reductase locus is confined to the early S period in CHO cells synchronized with the plant amino acid mimosine , 1992, Molecular and cellular biology.

[27]  J. Hamlin,et al.  Activation of a mammalian origin of replication by chromosomal rearrangement , 1992, Molecular and cellular biology.

[28]  J M Gale,et al.  Localization and DNA sequence of a replication origin in the rhodopsin gene locus of Chinese hamster cells. , 1992, Journal of molecular biology.

[29]  P. Dijkwel,et al.  Mapping of replication initiation sites in mammalian genomes by two-dimensional gel analysis: stabilization and enrichment of replication intermediates by isolation on the nuclear matrix , 1991, Molecular and cellular biology.

[30]  P. Krysan,et al.  Autonomous DNA replication in human cells is affected by the size and the source of the DNA , 1991, Molecular and cellular biology.

[31]  P. Krysan,et al.  Replication initiates at multiple locations on an autonomously replicating plasmid in human cells , 1991, Molecular and cellular biology.

[32]  L. Vassilev,et al.  Identification of an origin of bidirectional DNA replication in mammalian chromosomes , 1990, Cell.

[33]  M. DePamphilis,et al.  Mapping an origin of DNA replication at a single-copy locus in exponentially proliferating mammalian cells , 1990, Molecular and cellular biology.

[34]  P. Dijkwel,et al.  Replication initiates in a broad zone in the amplified CHO dihydrofolate reductase domain , 1990, Cell.

[35]  J. Hamlin,et al.  Multiple origins of replication in the dihydrofolate reductase amplicons of a methotrexate-resistant chinese hamster cell line , 1990, Molecular and cellular biology.

[36]  A. Spradling,et al.  Multiple replication origins are used during Drosophila chorion gene amplification , 1990, The Journal of cell biology.

[37]  F. Kafatos,et al.  Amplification-control element ACE-3 is important but not essential for autosomal chorion gene amplification. , 1989, Proceedings of the National Academy of Sciences of the United States of America.

[38]  H. Cedar,et al.  Mapping replication units in animal cells , 1989, Cell.

[39]  S. Haase,et al.  Isolation of human sequences that replicate autonomously in human cells , 1989, Molecular and cellular biology.

[40]  F. Kafatos,et al.  Amplification enhancers and replication origins in the autosomal chorion gene cluster of Drosophila. , 1989, EMBO Journal.

[41]  J. Hamlin,et al.  Replication in the amplified dihydrofolate reductase domain in CHO cells may initiate at two distinct sites, one of which is a repetitive sequence element , 1989, Molecular and cellular biology.

[42]  J. Hamlin,et al.  High-resolution mapping of replication fork movement through the amplified dihydrofolate reductase domain in CHO cells by in-gel renaturation analysis , 1989, Molecular and cellular biology.

[43]  P. Dijkwel,et al.  Matrix attachment regions are positioned near replication initiation sites, genes, and an interamplicon junction in the amplified dihydrofolate reductase domain of Chinese hamster ovary cells , 1988, Molecular and cellular biology.

[44]  N. Henderson,et al.  Site-specific DNA recombination in mammalian cells by the Cre recombinase of bacteriophage P1. , 1988, Proceedings of the National Academy of Sciences of the United States of America.

[45]  R. W. Davis,et al.  Transcription interferes with elements important for chromosome maintenance in Saccharomyces cerevisiae , 1988, Molecular and cellular biology.

[46]  J. Huberman,et al.  Two-dimensional gel electrophoretic method for mapping DNA replicons , 1988, Molecular and cellular biology.

[47]  J. Blow,et al.  Chromosome replication in cell-free systems from Xenopus eggs. , 1987, Philosophical transactions of the Royal Society of London. Series B, Biological sciences.

[48]  W. L. Fangman,et al.  The localization of replication origins on ARS plasmids in S. cerevisiae , 1987, Cell.

[49]  F. Kafatos,et al.  Amplification of a chorion gene cluster in Drosophila is subject to multiple cis-regulatory elements and to long-range position effects. , 1987, Journal of molecular biology.

[50]  K. Skarstad,et al.  Mode of initiation of constitutive stable DNA replication in RNase H-defective mutants of Escherichia coli K-12 , 1987, Journal of bacteriology.

[51]  G. Wahl,et al.  Cosmid vectors for rapid genomic walking, restriction mapping, and gene transfer. , 1987, Proceedings of the National Academy of Sciences of the United States of America.

[52]  J. Blow,et al.  Initiation of DNA replication in nuclei and purified DNA by a cell-free extract of Xenopus eggs , 1986, Cell.

[53]  W. Burhans,et al.  Isolation of the origin of replication associated with the amplified Chinese hamster dihydrofolate reductase domain. , 1986, Proceedings of the National Academy of Sciences of the United States of America.

[54]  J. Campbell.  Eukaryotic DNA replication. , 1986, Annual review of biochemistry.

[55]  E. Käs,et al.  Deletion of the diploid dihydrofolate reductase locus from cultured mammalian cells , 1983, Cell.

[56]  H. Bujard,et al.  Transcription from efficient promoters can interfere with plasmid replication and diminish expression of plasmid specified genes. , 1982, The EMBO journal.

[57]  J. Hamlin,et al.  An amplified chromosomal sequence that includes the gene for dihydrofolate reductase initiates replication within specific restriction fragments. , 1982, Proceedings of the National Academy of Sciences of the United States of America.

[58]  R. Harland,et al.  Regulated replication of DNA microinjected into eggs of Xenopus laevis , 1980, Cell.

[59]  Michael Freeling,et al.  The anaerobic proteins of maize , 1980, Cell.

[60]  L. Chasin,et al.  Isolation of Chinese hamster cell mutants deficient in dihydrofolate reductase activity. , 1980, Proceedings of the National Academy of Sciences of the United States of America.

[61]  Robert G. Martin,et al.  The initiation of SV40 DNA synthesis is not unique to the replication origin , 1980, Cell.

[62]  F. Tamanoi,et al.  Physical mapping of primary and secondary origins of bacteriophage T7 DNA replication. , 1980, Proceedings of the National Academy of Sciences of the United States of America.